BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 50047001
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142932 (CHEMBL3759842) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142937 (CHEMBL3759726) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142935 (CHEMBL3759195) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142936 (CHEMBL3758384) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142930 (CHEMBL3759435) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142933 (CHEMBL3759275) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142931 (CHEMBL3759752) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50142934 (CHEMBL3758478) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-2 in mouse J774 cells assessed as reduction in LPS-induced PGE2 level incubated for 24 hrs by radio immunoassay				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142930 (CHEMBL3759435) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142931 (CHEMBL3759752) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142932 (CHEMBL3759842) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142934 (CHEMBL3758478) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142935 (CHEMBL3759195) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142936 (CHEMBL3758384) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142937 (CHEMBL3759726) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50142933 (CHEMBL3759275) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of COX-1 in mouse J774 cells assessed as reduction in PGE2 level using arachidonic acid as substrate preincubated for 15 mins followed by ...				Eur J Med Chem 109: 99-106 (2016) Article DOI: 10.1016/j.ejmech.2015.12.044 BindingDB Entry DOI: 10.7270/Q2Q2423H
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair