Compile Data Set for Download or QSAR

Found 207 hits Enz. Inhib. hit(s) with all data for entry = 50049296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238516 (CHEMBL4083752) Show SMILES CCn1nc(cc1-c1cccnn1)-c1cccc2ccncc12 Show InChI InChI=1S/C18H15N5/c1-2-23-18(16-7-4-9-20-21-16)11-17(22-23)14-6-3-5-13-8-10-19-12-15(13)14/h3-12H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238519 (CHEMBL4084723) Show SMILES CCn1nc(cc1-c1cccnn1)-c1ccnc2ccccc12 Show InChI InChI=1S/C18H15N5/c1-2-23-18(16-8-5-10-20-21-16)12-17(22-23)14-9-11-19-15-7-4-3-6-13(14)15/h3-12H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238474 (CHEMBL4096374) Show SMILES Cc1nc(sc1C(=O)N1CCOCC1)-c1cccc2ccccc12 Show InChI InChI=1S/C19H18N2O2S/c1-13-17(19(22)21-9-11-23-12-10-21)24-18(20-13)16-8-4-6-14-5-2-3-7-15(14)16/h2-8H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238483 (CHEMBL4093978) Show SMILES CCn1nc(cc1-c1nccn1C)-c1cccc2ccccc12 Show InChI InChI=1S/C19H18N4/c1-3-23-18(19-20-11-12-22(19)2)13-17(21-23)16-10-6-8-14-7-4-5-9-15(14)16/h4-13H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238466 (CHEMBL4086216) Show SMILES CCn1nc(cc1-c1ncccn1)-c1cccc2ccccc12 Show InChI InChI=1S/C19H16N4/c1-2-23-18(19-20-11-6-12-21-19)13-17(22-23)16-10-5-8-14-7-3-4-9-15(14)16/h3-13H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238461 (CHEMBL4062681) Show SMILES CN(CCc1cccnc1)C(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C23H21N3OS/c1-16-21(23(27)26(2)14-12-17-7-6-13-24-15-17)28-22(25-16)20-11-5-9-18-8-3-4-10-19(18)20/h3-11,13,15H,12,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238470 (CHEMBL4064423) Show SMILES CN1CCN(CC1)C(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C20H21N3OS/c1-14-18(20(24)23-12-10-22(2)11-13-23)25-19(21-14)17-9-5-7-15-6-3-4-8-16(15)17/h3-9H,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238492 (CHEMBL4092473) Show SMILES CCn1nc(cc1-c1cccnn1)-c1nccc2ccccc12 Show InChI InChI=1S/C18H15N5/c1-2-23-17(15-8-5-10-20-21-15)12-16(22-23)18-14-7-4-3-6-13(14)9-11-19-18/h3-12H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238524 (CHEMBL4078330) Show SMILES O=C(N1CCOCC1)c1nc(cs1)-c1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2S/c21-18(20-8-10-22-11-9-20)17-19-16(12-23-17)15-7-3-5-13-4-1-2-6-14(13)15/h1-7,12H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238500 (CHEMBL4082829) Show SMILES Cc1sc(cc1C(=O)N1CCC(CO)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C22H23NO2S/c1-15-20(22(25)23-11-9-16(14-24)10-12-23)13-21(26-15)19-8-4-6-17-5-2-3-7-18(17)19/h2-8,13,16,24H,9-12,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238466 (CHEMBL4086216) Show SMILES CCn1nc(cc1-c1ncccn1)-c1cccc2ccccc12 Show InChI InChI=1S/C19H16N4/c1-2-23-18(19-20-11-6-12-21-19)13-17(22-23)16-10-5-8-14-7-3-4-9-15(14)16/h3-13H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238520 (CHEMBL4073363) Show SMILES CCn1nc(cc1-c1ccc(N)nn1)-c1cccc2ccncc12 Show InChI InChI=1S/C18H16N6/c1-2-24-17(15-6-7-18(19)22-21-15)10-16(23-24)13-5-3-4-12-8-9-20-11-14(12)13/h3-11H,2H2,1H3,(H2,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238503 (CHEMBL4081863) Show SMILES Cc1nc(sc1C(=O)N1CCC(CO)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C21H22N2O2S/c1-14-19(21(25)23-11-9-15(13-24)10-12-23)26-20(22-14)18-8-4-6-16-5-2-3-7-17(16)18/h2-8,15,24H,9-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238504 (CHEMBL4082709) Show SMILES Cc1nc(sc1C(N)=O)-c1cccc2ccccc12 Show InChI InChI=1S/C15H12N2OS/c1-9-13(14(16)18)19-15(17-9)12-8-4-6-10-5-2-3-7-11(10)12/h2-8H,1H3,(H2,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238506 (CHEMBL4062011) Show SMILES CCn1nc(cc1-c1cccnn1)-c1cccc2cnccc12 Show InChI InChI=1S/C18H15N5/c1-2-23-18(16-7-4-9-20-21-16)11-17(22-23)15-6-3-5-13-12-19-10-8-14(13)15/h3-12H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238480 (CHEMBL4100745) Show SMILES Cn1nc(cc1-c1cccnn1)-c1cccc2ccccc12 Show InChI InChI=1S/C18H14N4/c1-22-18(16-10-5-11-19-20-16)12-17(21-22)15-9-4-7-13-6-2-3-8-14(13)15/h2-12H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238513 (CHEMBL4102342) Show SMILES Clc1cccc(-c2nc(cs2)C(=O)N2CCCOCC2)c1Cl Show InChI InChI=1S/C15H14Cl2N2O2S/c16-11-4-1-3-10(13(11)17)14-18-12(9-22-14)15(20)19-5-2-7-21-8-6-19/h1,3-4,9H,2,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238471 (CHEMBL4091448) Show SMILES COCCN(C)C(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C19H20N2O2S/c1-13-17(19(22)21(2)11-12-23-3)24-18(20-13)16-10-6-8-14-7-4-5-9-15(14)16/h4-10H,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238523 (CHEMBL4096385) Show SMILES CCn1nc(cc1-c1ncnn1C)-c1cccc2ccccc12 Show InChI InChI=1S/C18H17N5/c1-3-23-17(18-19-12-20-22(18)2)11-16(21-23)15-10-6-8-13-7-4-5-9-14(13)15/h4-12H,3H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238477 (CHEMBL4068476) Show SMILES Cc1nc(sc1C(=O)N1CCCC(O)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C21H22N2O2S/c1-14-19(21(25)23-12-5-8-16(24)11-13-23)26-20(22-14)18-10-4-7-15-6-2-3-9-17(15)18/h2-4,6-7,9-10,16,24H,5,8,11-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238496 (CHEMBL4105011) Show SMILES Clc1cccc(-c2ncc(s2)C(=O)N2CCOCC2)c1Cl Show InChI InChI=1S/C14H12Cl2N2O2S/c15-10-3-1-2-9(12(10)16)13-17-8-11(21-13)14(19)18-4-6-20-7-5-18/h1-3,8H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238507 (CHEMBL4096587) Show SMILES Cc1nn(nc1C(=O)N1CCC(CO)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C20H22N4O2/c1-14-19(20(26)23-11-9-15(13-25)10-12-23)22-24(21-14)18-8-4-6-16-5-2-3-7-17(16)18/h2-8,15,25H,9-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238497 (CHEMBL4059884) Show SMILES Clc1ccc(-c2nc(cs2)C(=O)N2CCOCC2)c(Cl)c1 Show InChI InChI=1S/C14H12Cl2N2O2S/c15-9-1-2-10(11(16)7-9)13-17-12(8-21-13)14(19)18-3-5-20-6-4-18/h1-2,7-8H,3-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238459 (CHEMBL4103426) Show SMILES Cc1cn(cc1C(=O)N1CCC(CO)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C22H24N2O2/c1-16-13-24(21-8-4-6-18-5-2-3-7-19(18)21)14-20(16)22(26)23-11-9-17(15-25)10-12-23/h2-8,13-14,17,25H,9-12,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238516 (CHEMBL4083752) Show SMILES CCn1nc(cc1-c1cccnn1)-c1cccc2ccncc12 Show InChI InChI=1S/C18H15N5/c1-2-23-18(16-7-4-9-20-21-16)11-17(22-23)14-6-3-5-13-8-10-19-12-15(13)14/h3-12H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238515 (CHEMBL4064770) Show SMILES CCn1nc(cc1-c1cccnn1)-c1cncc2ccccc12 Show InChI InChI=1S/C18H15N5/c1-2-23-18(16-8-5-9-20-21-16)10-17(22-23)15-12-19-11-13-6-3-4-7-14(13)15/h3-12H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238502 (CHEMBL4099179) Show SMILES CN(C)C(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C17H16N2OS/c1-11-15(17(20)19(2)3)21-16(18-11)14-10-6-8-12-7-4-5-9-13(12)14/h4-10H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238519 (CHEMBL4084723) Show SMILES CCn1nc(cc1-c1cccnn1)-c1ccnc2ccccc12 Show InChI InChI=1S/C18H15N5/c1-2-23-18(16-8-5-10-20-21-16)12-17(22-23)14-9-11-19-15-7-4-3-6-13(14)15/h3-12H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	315	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238496 (CHEMBL4105011) Show SMILES Clc1cccc(-c2ncc(s2)C(=O)N2CCOCC2)c1Cl Show InChI InChI=1S/C14H12Cl2N2O2S/c15-10-3-1-2-9(12(10)16)13-17-8-11(21-13)14(19)18-4-6-20-7-5-18/h1-3,8H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238492 (CHEMBL4092473) Show SMILES CCn1nc(cc1-c1cccnn1)-c1nccc2ccccc12 Show InChI InChI=1S/C18H15N5/c1-2-23-17(15-8-5-10-20-21-15)12-16(22-23)18-14-7-4-3-6-13(14)9-11-19-18/h3-12H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	291	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238486 (CHEMBL4088662) Show SMILES Cc1sc(nc1C(=O)N1CCOCC1)-c1cccc(Cl)c1Cl Show InChI InChI=1S/C15H14Cl2N2O2S/c1-9-13(15(20)19-5-7-21-8-6-19)18-14(22-9)10-3-2-4-11(16)12(10)17/h2-4H,5-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238489 (CHEMBL4065606) Show SMILES Cc1oc(nc1C(=O)N1CCC(CO)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C21H22N2O3/c1-14-19(21(25)23-11-9-15(13-24)10-12-23)22-20(26-14)18-8-4-6-16-5-2-3-7-17(16)18/h2-8,15,24H,9-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	381	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238514 (CHEMBL4095818) Show SMILES Cc1nc(sc1C(=O)N1CCC(O)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C20H20N2O2S/c1-13-18(20(24)22-11-9-15(23)10-12-22)25-19(21-13)17-8-4-6-14-5-2-3-7-16(14)17/h2-8,15,23H,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238479 (CHEMBL4072217) Show SMILES Cc1nc(sc1C(=O)N1CCCCC1)-c1cccc2ccccc12 Show InChI InChI=1S/C20H20N2OS/c1-14-18(20(23)22-12-5-2-6-13-22)24-19(21-14)17-11-7-9-15-8-3-4-10-16(15)17/h3-4,7-11H,2,5-6,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238497 (CHEMBL4059884) Show SMILES Clc1ccc(-c2nc(cs2)C(=O)N2CCOCC2)c(Cl)c1 Show InChI InChI=1S/C14H12Cl2N2O2S/c15-9-1-2-10(11(16)7-9)13-17-12(8-21-13)14(19)18-3-5-20-6-4-18/h1-2,7-8H,3-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238480 (CHEMBL4100745) Show SMILES Cn1nc(cc1-c1cccnn1)-c1cccc2ccccc12 Show InChI InChI=1S/C18H14N4/c1-22-18(16-10-5-11-19-20-16)12-17(21-22)15-9-4-7-13-6-2-3-8-14(13)15/h2-12H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238457 (CHEMBL4069354) Show SMILES OCC1CCN(CC1)C(=O)c1nnn(n1)-c1cccc2ccccc12 Show InChI InChI=1S/C18H19N5O2/c24-12-13-8-10-22(11-9-13)18(25)17-19-21-23(20-17)16-7-3-5-14-4-1-2-6-15(14)16/h1-7,13,24H,8-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238460 (CHEMBL4070587) Show SMILES CCn1nc(cc1-c1cncn1C)-c1cccc2ccccc12 Show InChI InChI=1S/C19H18N4/c1-3-23-18(19-12-20-13-22(19)2)11-17(21-23)16-10-6-8-14-7-4-5-9-15(14)16/h4-13H,3H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238474 (CHEMBL4096374) Show SMILES Cc1nc(sc1C(=O)N1CCOCC1)-c1cccc2ccccc12 Show InChI InChI=1S/C19H18N2O2S/c1-13-17(19(22)21-9-11-23-12-10-21)24-18(20-13)16-8-4-6-14-5-2-3-7-15(14)16/h2-8H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238481 (CHEMBL4072337) Show SMILES Cn1cc(cc1C(=O)N1CCC(CO)CC1)-c1cccc2ccccc12 Show InChI InChI=1S/C22H24N2O2/c1-23-14-18(20-8-4-6-17-5-2-3-7-19(17)20)13-21(23)22(26)24-11-9-16(15-25)10-12-24/h2-8,13-14,16,25H,9-12,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238485 (CHEMBL4062529) Show SMILES Cc1sc(nc1C(=O)N1CCOCC1)-c1cccc2ccccc12 Show InChI InChI=1S/C19H18N2O2S/c1-13-17(19(22)21-9-11-23-12-10-21)20-18(24-13)16-8-4-6-14-5-2-3-7-15(14)16/h2-8H,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238517 (CHEMBL4061625) Show SMILES Clc1ccccc1-c1nc(cs1)C(=O)N1CCOCC1 Show InChI InChI=1S/C14H13ClN2O2S/c15-11-4-2-1-3-10(11)13-16-12(9-20-13)14(18)17-5-7-19-8-6-17/h1-4,9H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238523 (CHEMBL4096385) Show SMILES CCn1nc(cc1-c1ncnn1C)-c1cccc2ccccc12 Show InChI InChI=1S/C18H17N5/c1-3-23-17(18-19-12-20-22(18)2)11-16(21-23)15-10-6-8-13-7-4-5-9-14(13)15/h4-12H,3H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238486 (CHEMBL4088662) Show SMILES Cc1sc(nc1C(=O)N1CCOCC1)-c1cccc(Cl)c1Cl Show InChI InChI=1S/C15H14Cl2N2O2S/c1-9-13(15(20)19-5-7-21-8-6-19)18-14(22-9)10-3-2-4-11(16)12(10)17/h2-4H,5-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238518 (CHEMBL4083432) Show SMILES Clc1cccc(-c2nc(cs2)C(=O)N2CC3CC2CO3)c1Cl Show InChI InChI=1S/C15H12Cl2N2O2S/c16-11-3-1-2-10(13(11)17)14-18-12(7-22-14)15(20)19-5-9-4-8(19)6-21-9/h1-3,7-9H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238487 (CHEMBL4062613) Show SMILES Fc1c(Cl)cccc1-c1nc(cs1)C(=O)N1CCOCC1 Show InChI InChI=1S/C14H12ClFN2O2S/c15-10-3-1-2-9(12(10)16)13-17-11(8-21-13)14(19)18-4-6-20-7-5-18/h1-3,8H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238463 (CHEMBL4102653) Show SMILES CCn1nc(cc1-c1cccnn1)-c1cccc2ncccc12 Show InChI InChI=1S/C18H15N5/c1-2-23-18(16-9-5-11-20-21-16)12-17(22-23)14-6-3-8-15-13(14)7-4-10-19-15/h3-12H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238488 (CHEMBL4081550) Show SMILES CCn1nc(cc1-c1ccnn1C)-c1cccc2ccccc12 Show InChI InChI=1S/C19H18N4/c1-3-23-19(18-11-12-20-22(18)2)13-17(21-23)16-10-6-8-14-7-4-5-9-15(14)16/h4-13H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of serotonin (5-HT) uptake into rat brain synaptosomes				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238456 (CHEMBL4092132) Show SMILES Clc1cccc(-c2nc(cs2)C(=O)N2CCCCC2)c1Cl Show InChI InChI=1S/C15H14Cl2N2OS/c16-11-6-4-5-10(13(11)17)14-18-12(9-21-14)15(20)19-7-2-1-3-8-19/h4-6,9H,1-3,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238482 (CHEMBL4065444) Show SMILES Clc1cccc(-c2nc(cs2)C(=O)N2CCOCC2)c1Cl Show InChI InChI=1S/C14H12Cl2N2O2S/c15-10-3-1-2-9(12(10)16)13-17-11(8-21-13)14(19)18-4-6-20-7-5-18/h1-3,8H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair

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