Compile Data Set for Download or QSAR

Found 117 hits Enz. Inhib. hit(s) with all data for entry = 614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282619 (US9884828, 2-114) Show SMILES CN(C)C(=O)c1ccc(cc1)-c1ccc2cc(nnc2c1)C(N)=O Show InChI InChI=1S/C18H16N4O2/c1-22(2)18(24)12-5-3-11(4-6-12)13-7-8-14-10-16(17(19)23)21-20-15(14)9-13/h3-10H,1-2H3,(H2,19,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282606 (US9884828, 2-101) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1cnn(C)c1)C(N)=O)C1CC1 Show InChI InChI=1S/C18H20N6O/c1-10(11-3-4-11)21-16-14-6-5-12(13-8-20-24(2)9-13)7-15(14)22-23-17(16)18(19)25/h5-11H,3-4H2,1-2H3,(H2,19,25)(H,21,22)/t10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282670 (US9884828, 9-213) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccc(cc1)N1CCOC1=O)C(N)=O)C1CC1 Show InChI InChI=1S/C23H23N5O3/c1-13(14-2-3-14)25-20-18-9-6-16(12-19(18)26-27-21(20)22(24)29)15-4-7-17(8-5-15)28-10-11-31-23(28)30/h4-9,12-14H,2-3,10-11H2,1H3,(H2,24,29)(H,25,26)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282625 (US9884828, 2-120) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccc2CC(=O)Nc2c1)C(N)=O)C1CC1 Show InChI InChI=1S/C22H21N5O2/c1-11(12-2-3-12)24-20-16-7-6-14(9-18(16)26-27-21(20)22(23)29)13-4-5-15-10-19(28)25-17(15)8-13/h4-9,11-12H,2-3,10H2,1H3,(H2,23,29)(H,24,26)(H,25,28)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282616 (US9884828, 2-111) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1cccc(c1)S(C)(=O)=O)C(N)=O)C1CC1 Show InChI InChI=1S/C21H22N4O3S/c1-12(13-6-7-13)23-19-17-9-8-15(11-18(17)24-25-20(19)21(22)26)14-4-3-5-16(10-14)29(2,27)28/h3-5,8-13H,6-7H2,1-2H3,(H2,22,26)(H,23,24)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282626 (US9884828, 2-121) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1cccc2CC(=O)Nc12)C(N)=O)C1CC1 Show InChI InChI=1S/C22H21N5O2/c1-11(12-5-6-12)24-20-16-8-7-13(9-17(16)26-27-21(20)22(23)29)15-4-2-3-14-10-18(28)25-19(14)15/h2-4,7-9,11-12H,5-6,10H2,1H3,(H2,23,29)(H,24,26)(H,25,28)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428717 (CHEMBL2333127 | US9884828, 2-37) Show SMILES CC[C@@H](C)Nc1c(nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O |r| Show InChI InChI=1S/C20H22N4O3S/c1-4-12(2)22-18-16-10-7-14(11-17(16)23-24-19(18)20(21)25)13-5-8-15(9-6-13)28(3,26)27/h5-12H,4H2,1-3H3,(H2,21,25)(H,22,23)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<6	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428703 (CHEMBL2333113 | US9884828, 2-100) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccncc1)C(N)=O)C1CC1 |r| Show InChI InChI=1S/C19H19N5O/c1-11(12-2-3-12)22-17-15-5-4-14(13-6-8-21-9-7-13)10-16(15)23-24-18(17)19(20)25/h4-12H,2-3H2,1H3,(H2,20,25)(H,22,23)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<6	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282607 (US9884828, 2-102) Show SMILES CN(C)C(=O)c1cccc(c1)-c1ccc2cc(nnc2c1)C(N)=O Show InChI InChI=1S/C18H16N4O2/c1-22(2)18(24)14-5-3-4-11(8-14)12-6-7-13-10-16(17(19)23)21-20-15(13)9-12/h3-10H,1-2H3,(H2,19,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<6	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428716 (CHEMBL2333128 | US9884828, 2-41) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O)C1CC1 |r| Show InChI InChI=1S/C21H22N4O3S/c1-12(13-3-4-13)23-19-17-10-7-15(11-18(17)24-25-20(19)21(22)26)14-5-8-16(9-6-14)29(2,27)28/h5-13H,3-4H2,1-2H3,(H2,22,26)(H,23,24)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<6	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282617 (US9884828, 2-112) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccc(=O)n(C)c1)C(N)=O)C1CC1 Show InChI InChI=1S/C20H21N5O2/c1-11(12-3-4-12)22-18-15-7-5-13(14-6-8-17(26)25(2)10-14)9-16(15)23-24-19(18)20(21)27/h5-12H,3-4H2,1-2H3,(H2,21,27)(H,22,23)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<6	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428701 (CHEMBL2333115 | US9884828, 2-127) Show SMILES CC(C)Nc1c(nnc2ccc(cc12)-c1cn[nH]c1)C(N)=O Show InChI InChI=1S/C15H16N6O/c1-8(2)19-13-11-5-9(10-6-17-18-7-10)3-4-12(11)20-21-14(13)15(16)22/h3-8H,1-2H3,(H2,16,22)(H,17,18)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<6	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282627 (US9884828, 2-122) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccn(C)c(=O)c1)C(N)=O)C1CC1 Show InChI InChI=1S/C20H21N5O2/c1-11(12-3-4-12)22-18-15-6-5-13(14-7-8-25(2)17(26)10-14)9-16(15)23-24-19(18)20(21)27/h5-12H,3-4H2,1-2H3,(H2,21,27)(H,22,23)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282589 (US9884828, 2-49) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1ccc(cc1)N1CCOCC1)C(N)=O Show InChI InChI=1S/C22H25N5O2/c1-14(2)24-20-18-8-5-16(13-19(18)25-26-21(20)22(23)28)15-3-6-17(7-4-15)27-9-11-29-12-10-27/h3-8,13-14H,9-12H2,1-2H3,(H2,23,28)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428700 (CHEMBL2333116 | US9884828, 2-53) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1cn[nH]c1)C(N)=O Show InChI InChI=1S/C15H16N6O/c1-8(2)19-13-11-4-3-9(10-6-17-18-7-10)5-12(11)20-21-14(13)15(16)22/h3-8H,1-2H3,(H2,16,22)(H,17,18)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282674 (US9884828, 11-221) Show SMILES COc1cc(ccc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)-c1nccn1C Show InChI InChI=1S/C25H26N6O2/c1-14(15-4-5-15)28-22-19-9-6-16(12-20(19)29-30-23(22)24(26)32)18-8-7-17(13-21(18)33-3)25-27-10-11-31(25)2/h6-15H,4-5H2,1-3H3,(H2,26,32)(H,28,29)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428698 (CHEMBL2333118 | US9884828, 2-35) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1cnn(C)c1)C(N)=O Show InChI InChI=1S/C16H18N6O/c1-9(2)19-14-12-5-4-10(11-7-18-22(3)8-11)6-13(12)20-21-15(14)16(17)23/h4-9H,1-3H3,(H2,17,23)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428715 (CHEMBL2333129 | US9884828, 2-19) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(NC3CCC3)c(nnc2c1)C(N)=O Show InChI InChI=1S/C20H20N4O3S/c1-28(26,27)15-8-5-12(6-9-15)13-7-10-16-17(11-13)23-24-19(20(21)25)18(16)22-14-3-2-4-14/h5-11,14H,2-4H2,1H3,(H2,21,25)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282615 (US9884828, 2-110) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccccc1)C(N)=O)C1CC1 Show InChI InChI=1S/C20H20N4O/c1-12(13-7-8-13)22-18-16-10-9-15(14-5-3-2-4-6-14)11-17(16)23-24-19(18)20(21)25/h2-6,9-13H,7-8H2,1H3,(H2,21,25)(H,22,23)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282623 (US9884828, 2-118) Show SMILES COc1cc(ccc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)C(=O)N(C)C Show InChI InChI=1S/C24H27N5O3/c1-13(14-5-6-14)26-21-18-10-7-15(11-19(18)27-28-22(21)23(25)30)17-9-8-16(12-20(17)32-4)24(31)29(2)3/h7-14H,5-6H2,1-4H3,(H2,25,30)(H,26,27)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282621 (US9884828, 2-116) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccc(cc1)N1CCOCC1=O)C(N)=O)C1CC1 Show InChI InChI=1S/C24H25N5O3/c1-14(15-2-3-15)26-22-19-9-6-17(12-20(19)27-28-23(22)24(25)31)16-4-7-18(8-5-16)29-10-11-32-13-21(29)30/h4-9,12,14-15H,2-3,10-11,13H2,1H3,(H2,25,31)(H,26,27)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282611 (US9884828, 2-106) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccc2NC(=O)Cc2c1)C(N)=O)C1CC1 Show InChI InChI=1S/C22H21N5O2/c1-11(12-2-3-12)24-20-16-6-4-14(9-18(16)26-27-21(20)22(23)29)13-5-7-17-15(8-13)10-19(28)25-17/h4-9,11-12H,2-3,10H2,1H3,(H2,23,29)(H,24,26)(H,25,28)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282661 (US9884828, 5-55) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1c[nH]nn1)C(N)=O Show InChI InChI=1S/C14H15N7O/c1-7(2)17-12-9-4-3-8(11-6-16-21-19-11)5-10(9)18-20-13(12)14(15)22/h3-7H,1-2H3,(H2,15,22)(H,17,18)(H,16,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428704 (CHEMBL2333112 | US9884828, 2-31) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1ccncc1)C(N)=O Show InChI InChI=1S/C17H17N5O/c1-10(2)20-15-13-4-3-12(11-5-7-19-8-6-11)9-14(13)21-22-16(15)17(18)23/h3-10H,1-2H3,(H2,18,23)(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428718 (CHEMBL2333126 | US9884828, 2-17) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O Show InChI InChI=1S/C19H20N4O3S/c1-11(2)21-17-15-9-6-13(10-16(15)22-23-18(17)19(20)24)12-4-7-14(8-5-12)27(3,25)26/h4-11H,1-3H3,(H2,20,24)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282590 (US9884828, 2-51) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1cccc(c1)N1CCOCC1)C(N)=O Show InChI InChI=1S/C22H25N5O2/c1-14(2)24-20-18-7-6-16(13-19(18)25-26-21(20)22(23)28)15-4-3-5-17(12-15)27-8-10-29-11-9-27/h3-7,12-14H,8-11H2,1-2H3,(H2,23,28)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428710 (CHEMBL2333134 | US9884828, 2-23) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(NC3CCOC3)c(nnc2c1)C(N)=O Show InChI InChI=1S/C20H20N4O4S/c1-29(26,27)15-5-2-12(3-6-15)13-4-7-16-17(10-13)23-24-19(20(21)25)18(16)22-14-8-9-28-11-14/h2-7,10,14H,8-9,11H2,1H3,(H2,21,25)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428714 (CHEMBL2333130 | US9884828, 2-92) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(NCC3CC3)c(nnc2c1)C(N)=O Show InChI InChI=1S/C20H20N4O3S/c1-28(26,27)15-7-4-13(5-8-15)14-6-9-16-17(10-14)23-24-19(20(21)25)18(16)22-11-12-2-3-12/h4-10,12H,2-3,11H2,1H3,(H2,21,25)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282624 (US9884828, 2-119) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1cccc2NC(=O)Cc12)C(N)=O)C1CC1 Show InChI InChI=1S/C22H21N5O2/c1-11(12-5-6-12)24-20-15-8-7-13(9-18(15)26-27-21(20)22(23)29)14-3-2-4-17-16(14)10-19(28)25-17/h2-4,7-9,11-12H,5-6,10H2,1H3,(H2,23,29)(H,24,26)(H,25,28)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428712 (CHEMBL2333132 | US9884828, 2-25) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(NC3CCOCC3)c(nnc2c1)C(N)=O Show InChI InChI=1S/C21H22N4O4S/c1-30(27,28)16-5-2-13(3-6-16)14-4-7-17-18(12-14)24-25-20(21(22)26)19(17)23-15-8-10-29-11-9-15/h2-7,12,15H,8-11H2,1H3,(H2,22,26)(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282673 (US9884828, 11-220) Show SMILES COc1cc(ccc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)-c1nccnc1OC Show InChI InChI=1S/C26H26N6O3/c1-14(15-4-5-15)30-23-19-9-6-16(12-20(19)31-32-24(23)25(27)33)18-8-7-17(13-21(18)34-2)22-26(35-3)29-11-10-28-22/h6-15H,4-5H2,1-3H3,(H2,27,33)(H,30,31)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282639 (US9884828, 2-134) Show SMILES CCC(CC)Nc1c(nnc2cc(ccc12)-c1ccncc1)C(N)=O Show InChI InChI=1S/C19H21N5O/c1-3-14(4-2)22-17-15-6-5-13(12-7-9-21-10-8-12)11-16(15)23-24-18(17)19(20)25/h5-11,14H,3-4H2,1-2H3,(H2,20,25)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428702 (CHEMBL2333114 | US9884828, 2-126) Show SMILES CC(C)Nc1c(nnc2ccc(cc12)-c1ccncc1)C(N)=O Show InChI InChI=1S/C17H17N5O/c1-10(2)20-15-13-9-12(11-5-7-19-8-6-11)3-4-14(13)21-22-16(15)17(18)23/h3-10H,1-2H3,(H2,18,23)(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282654 (US9884828, 4-80) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-n1cccn1)C(N)=O Show InChI InChI=1S/C15H16N6O/c1-9(2)18-13-11-5-4-10(21-7-3-6-17-21)8-12(11)19-20-14(13)15(16)22/h3-9H,1-2H3,(H2,16,22)(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282658 (US9884828, 4-190) Show SMILES COc1ncccc1Nc1ccc2c(NC(C)C)c(nnc2c1)C(N)=O Show InChI InChI=1S/C18H20N6O2/c1-10(2)21-15-12-7-6-11(9-14(12)23-24-16(15)17(19)25)22-13-5-4-8-20-18(13)26-3/h4-10,22H,1-3H3,(H2,19,25)(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282592 (US9884828, 2-57) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1cccnc1)C(N)=O Show InChI InChI=1S/C17H17N5O/c1-10(2)20-15-13-6-5-11(12-4-3-7-19-9-12)8-14(13)21-22-16(15)17(18)23/h3-10H,1-2H3,(H2,18,23)(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282672 (US9884828, 11-218) Show SMILES COc1cc(ccc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)-c1ncccc1F Show InChI InChI=1S/C26H24FN5O2/c1-14(15-5-6-15)30-24-19-10-7-16(12-21(19)31-32-25(24)26(28)33)18-9-8-17(13-22(18)34-2)23-20(27)4-3-11-29-23/h3-4,7-15H,5-6H2,1-2H3,(H2,28,33)(H,30,31)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282596 (US9884828, 2-91) Show SMILES CC(C)(C)Nc1c(nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O Show InChI InChI=1S/C20H22N4O3S/c1-20(2,3)22-17-15-10-7-13(11-16(15)23-24-18(17)19(21)25)12-5-8-14(9-6-12)28(4,26)27/h5-11H,1-4H3,(H2,21,25)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428713 (CHEMBL2333131 | US9884828, 2-93) Show SMILES CCNc1c(nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O Show InChI InChI=1S/C18H18N4O3S/c1-3-20-16-14-9-6-12(10-15(14)21-22-17(16)18(19)23)11-4-7-13(8-5-11)26(2,24)25/h4-10H,3H2,1-2H3,(H2,19,23)(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282602 (US9884828, 2-97) Show SMILES COc1cccc(c1)-c1ccc2c(NC(C)C)c(nnc2c1)C(N)=O Show InChI InChI=1S/C19H20N4O2/c1-11(2)21-17-15-8-7-13(12-5-4-6-14(9-12)25-3)10-16(15)22-23-18(17)19(20)24/h4-11H,1-3H3,(H2,20,24)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428711 (CHEMBL2333133 | US9884828, 2-29) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(NC3CC3)c(nnc2c1)C(N)=O Show InChI InChI=1S/C19H18N4O3S/c1-27(25,26)14-7-2-11(3-8-14)12-4-9-15-16(10-12)22-23-18(19(20)24)17(15)21-13-5-6-13/h2-4,7-10,13H,5-6H2,1H3,(H2,20,24)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282612 (US9884828, 2-107) Show SMILES COc1ccc(cc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)C(=O)N(C)C Show InChI InChI=1S/C24H27N5O3/c1-13(14-5-6-14)26-21-17-9-7-15(12-19(17)27-28-22(21)23(25)30)18-11-16(24(31)29(2)3)8-10-20(18)32-4/h7-14H,5-6H2,1-4H3,(H2,25,30)(H,26,27)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282620 (US9884828, 2-115) Show SMILES COc1ccc(cc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)S(C)(=O)=O Show InChI InChI=1S/C22H24N4O4S/c1-12(13-4-5-13)24-20-16-8-6-14(10-18(16)25-26-21(20)22(23)27)17-11-15(31(3,28)29)7-9-19(17)30-2/h6-13H,4-5H2,1-3H3,(H2,23,27)(H,24,25)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282618 (US9884828, 2-113) Show SMILES NC(=O)c1cc2ccc(cc2nn1)-c1cccc(OCC2CC2)c1 Show InChI InChI=1S/C19H17N3O2/c20-19(23)18-10-15-7-6-14(9-17(15)21-22-18)13-2-1-3-16(8-13)24-11-12-4-5-12/h1-3,6-10,12H,4-5,11H2,(H2,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282678 (US9884828, 13-233) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)-c1ncc[nH]1 Show InChI InChI=1S/C21H21N5O2S/c1-13(2)24-19-17-9-6-15(14-4-7-16(8-5-14)29(3,27)28)12-18(17)25-26-20(19)21-22-10-11-23-21/h4-13H,1-3H3,(H,22,23)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50428697 (CHEMBL2333119 | US9884828, 4-188) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)N1CCN(C)CC1)C(N)=O Show InChI InChI=1S/C17H24N6O/c1-11(2)19-15-13-5-4-12(23-8-6-22(3)7-9-23)10-14(13)20-21-16(15)17(18)24/h4-5,10-11H,6-9H2,1-3H3,(H2,18,24)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282665 (US9884828, 9-206) Show SMILES COc1ccc(cc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)N1CCOC1=O Show InChI InChI=1S/C24H25N5O4/c1-13(14-3-4-14)26-21-17-7-5-15(11-19(17)27-28-22(21)23(25)30)18-12-16(6-8-20(18)32-2)29-9-10-33-24(29)31/h5-8,11-14H,3-4,9-10H2,1-2H3,(H2,25,30)(H,26,27)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282586 (US9884828, 2-43) Show SMILES CC(C)Nc1c(nnc2cc(ccc12)-c1ccc(F)cc1)C(N)=O Show InChI InChI=1S/C18H17FN4O/c1-10(2)21-16-14-8-5-12(11-3-6-13(19)7-4-11)9-15(14)22-23-17(16)18(20)24/h3-10H,1-2H3,(H2,20,24)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282668 (US9884828, 9-209) Show SMILES COc1ccc(cc1-c1ccc2c(N[C@H](C)C3CC3)c(nnc2c1)C(N)=O)N1CCOCC1=O Show InChI InChI=1S/C25H27N5O4/c1-14(15-3-4-15)27-23-18-7-5-16(11-20(18)28-29-24(23)25(26)32)19-12-17(6-8-21(19)33-2)30-9-10-34-13-22(30)31/h5-8,11-12,14-15H,3-4,9-10,13H2,1-2H3,(H2,26,32)(H,27,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM282595 (US9884828, 2-90) Show SMILES C[C@@H](Nc1c(nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O)C1CCOCC1 Show InChI InChI=1S/C23H26N4O4S/c1-14(15-9-11-31-12-10-15)25-21-19-8-5-17(13-20(19)26-27-22(21)23(24)28)16-3-6-18(7-4-16)32(2,29)30/h3-8,13-15H,9-12H2,1-2H3,(H2,24,28)(H,25,26)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair

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