Compile Data Set for Download or QSAR

Found 124 hits Enz. Inhib. hit(s) with all data for entry = 8924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429561 (US10550089, Example 35 | US10995072, Example 36) Show SMILES CCc1ccc2c(F)ccc([C@@H](O)c3ncc[nH]3)n12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429560 (US10550089, Example 34 | US10995072, Example 35) Show SMILES CCc1ccc2c(F)ccc(C(O)c3ncc[nH]3)n12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429568 (US10550089, Example 42 | US10995072, Example 42) Show SMILES CCc1coc2c(F)ccc([C@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429576 (US10550089, Example 50 | US10995072, Example 51) Show SMILES CCc1csc2c(F)ccc([C@@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429566 (US10550089, Example 40 | US10995072, Example 63) Show SMILES CCc1coc2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429544 (US10550089, Example 18 | US10995072, Example 18) Show SMILES O[C@@H](c1ncc[nH]1)c1ccc(F)cc1N1CC=CC1 |r,c:18| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429585 (US10550089, Example 59 | US10995072, Example 59) Show SMILES Cc1cccc2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429542 (US10550089, Example 16) Show SMILES O[C@H](c1ncc[nH]1)c1ccc(F)cc1N1CCCC1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429563 (US10550089, Example 37 | US10995072, Example 37) Show SMILES Cc1ccc2c(F)ccc(C(O)c3ncc[nH]3)n12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429577 (US10550089, Example 51) Show SMILES CCc1csc2c(F)ccc([C@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429543 (US10550089, Example 17 | US10995072, Example 17) Show SMILES OC(c1ncc[nH]1)c1ccc(F)cc1N1CC=CC1 |c:18| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429588 (US10550089, Example 62 | US10995072, Example 62) Show SMILES Cn1ncc2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429516 (US10550089, Example 3 | US10995072, Example 2) Show SMILES CCCc1cc(F)ccc1[C@@H](O)c1ncc[nH]1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429580 (US10550089, Example 54 | US10995072, Example 56) Show SMILES Cn1ccc2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429579 (US10550089, Example 53) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2oc3ccccc3c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429576 (US10550089, Example 50 | US10995072, Example 51) Show SMILES CCc1csc2c(F)ccc([C@@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429540 (US10550089, Example 14 | US10995072, Example 64) Show SMILES OC(c1ncc[nH]1)c1ccc(F)cc1N1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429561 (US10550089, Example 35 | US10995072, Example 36) Show SMILES CCc1ccc2c(F)ccc([C@@H](O)c3ncc[nH]3)n12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429578 (US10550089, Example 52 | US10995072, Example 52) Show SMILES Cc1coc2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429582 (US10550089, Example 56) Show SMILES Cn1ccc2c(F)ccc([C@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429536 (US10550089, Example 10 | US10995072, Example 11) Show SMILES CCCc1c(F)c(F)ccc1C(O)c1ncc[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429586 (US10550089, Example 60 | US10995072, Example 60) Show SMILES CCc1ccn2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429560 (US10550089, Example 34 | US10995072, Example 35) Show SMILES CCc1ccc2c(F)ccc(C(O)c3ncc[nH]3)n12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429564 (US10550089, Example 38 | US10995072, Example 38) Show SMILES CC(C)c1ccc2c(F)ccc(C(O)c3ncc[nH]3)n12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429573 (US10550089, Example 47 | US10995072, Example 47) Show SMILES O[C@@H](c1ncc[nH]1)c1ccc(F)c2occ(CC(F)(F)F)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429572 (US10550089, Example 46 | US10995072, Example 46) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(CC(F)(F)F)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429567 (US10550089, Example 41 | US10995072, Example 41) Show SMILES CCc1coc2c(F)ccc([C@@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429580 (US10550089, Example 54 | US10995072, Example 56) Show SMILES Cn1ccc2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429455 (US10550089, Example 1 | US10995072, Example 1) Show SMILES CCCc1cc(F)ccc1C(O)c1ncc[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429568 (US10550089, Example 42 | US10995072, Example 42) Show SMILES CCc1coc2c(F)ccc([C@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429586 (US10550089, Example 60 | US10995072, Example 60) Show SMILES CCc1ccn2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429563 (US10550089, Example 37 | US10995072, Example 37) Show SMILES Cc1ccc2c(F)ccc(C(O)c3ncc[nH]3)n12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429577 (US10550089, Example 51) Show SMILES CCc1csc2c(F)ccc([C@H](O)c3ncc[nH]3)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429587 (US10550089, Example 61) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2ccc(Cl)n12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429559 (US10550089, Example 33 | US10995072, Example 33) Show SMILES OC(c1ncc[nH]1)c1ccc(F)cc1-c1cscn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429552 ((4-Fluoro-2-((S)-3- fluoropyrrolidin-1- yl)phenyl)...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)cc1N1CC[C@H](F)C1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429516 (US10550089, Example 3 | US10995072, Example 2) Show SMILES CCCc1cc(F)ccc1[C@@H](O)c1ncc[nH]1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429538 (US10550089, Example 12) Show SMILES CCCc1c(F)c(F)ccc1[C@H](O)c1ncc[nH]1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429589 (US10550089, Example 63) Show SMILES CCc1coc2c(F)ccc(C(O)c3ncnn3COCC[Si](C)(C)C)c12 Show InChI InChI=1S/C19H26FN3O3Si/c1-5-13-10-26-18-15(20)7-6-14(16(13)18)17(24)19-21-11-22-23(19)12-25-8-9-27(2,3)4/h6-7,10-11,17,24H,5,8-9,12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429544 (US10550089, Example 18 | US10995072, Example 18) Show SMILES O[C@@H](c1ncc[nH]1)c1ccc(F)cc1N1CC=CC1 |r,c:18| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429557 (US10550089, Example 31 | US10995072, Example 31) Show SMILES OC(c1ncc[nH]1)c1ccc(F)cc1C12CC1CCC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429546 (US10550089, Example 20 | US10995072, Example 20) Show SMILES OC(c1ncc[nH]1)c1ccc(F)cc1N1CCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429569 (US10550089, Example 43 | US10550089, Example 44 | ...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429548 (US10550089, Example 22 | US10995072, Example 22) Show SMILES OC(c1ncc[nH]1)c1ccc(F)c(F)c1-n1cccn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429556 ((2-(3- Azabicyclo[3.1.0] hexan-3-yl)-4- fluorophen...) Show SMILES OC(c1ncc[nH]1)c1ccc(F)cc1N1CC2CC2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429566 (US10550089, Example 40 | US10995072, Example 63) Show SMILES CCc1coc2c(F)ccc(C(O)c3ncc[nH]3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429538 (US10550089, Example 12) Show SMILES CCCc1c(F)c(F)ccc1[C@H](O)c1ncc[nH]1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM429573 (US10550089, Example 47 | US10995072, Example 47) Show SMILES O[C@@H](c1ncc[nH]1)c1ccc(F)c2occ(CC(F)(F)F)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...				US Patent US10550089 (2020) BindingDB Entry DOI: 10.7270/Q2SB484T
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 124 total )  |  Next  |  Last  >>

Jump to: