Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241831![]() (CHEMBL4062273 | US10626113, Compound M | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0440 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241831![]() (CHEMBL4062273 | US10626113, Compound M | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0560 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241840![]() (CHEMBL4072903 | US10899756, Compound K) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0590 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480487![]() (US10626113, Compound D | US10899756, Compound D) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241832![]() (CHEMBL4083986 | US10626113, Compound C | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241842![]() (CHEMBL4064315 | US10899756, Compound M) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241835![]() (CHEMBL4092717 | US10899756, Compound AC) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50242157![]() (CHEMBL4070894 | US10626113, Compound B | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241834![]() (CHEMBL4065036 | US10626113, Compound J | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241837![]() (CHEMBL4102913 | US10626113, Compound G | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.55 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241843![]() (CHEMBL4102250 | US10899756, Compound N) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480506![]() (US10899756, Compound AB) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241841![]() (CHEMBL4092040 | US10899756, Compound L) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480489![]() (US10626113, Compound F | US10899756, Compound F) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480504![]() (US10626113, Compound O | US10899756, Compound W) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.6 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50242154![]() (CHEMBL4099788 | US10626113, Compound A | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 21.6 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480503![]() (US10626113, Compound N | US10899756, Compound V) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Homo sapiens (Human)) | BDBM480487![]() (US10626113, Compound D | US10899756, Compound D) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Homo sapiens (Human)) | BDBM50241831![]() (CHEMBL4062273 | US10626113, Compound M | US1089975...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 30.1 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480488![]() (US10626113, Compound E | US10899756, Compound E) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 43.8 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50242155![]() (CHEMBL4100445 | US10899756, Compound AA) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50242158![]() (CHEMBL4084285 | US10899756, Compound 0) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Homo sapiens (Human)) | BDBM50241837![]() (CHEMBL4102913 | US10626113, Compound G | US1089975...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50242156![]() (CHEMBL4096417 | US10899756, Compound P) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 333 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50241833![]() (CHEMBL4073617 | US10626113, Compound I | US1089975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 337 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480501![]() (US10626113, Compound L | US10899756, Compound T) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 425 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480500![]() (US10626113, Compound K | US10899756, Compound S) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 593 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Homo sapiens (Human)) | BDBM480488![]() (US10626113, Compound E | US10899756, Compound E) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair |