Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-mannosidase' and Ligand = 'BDBM50525016'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-mannosidase (Canavalia ensiformis)	BDBM50525016 (CHEMBL4457217) Show SMILES [H][C@]12COC(=O)N1[C@H](NCCCCCCCCCN=[N+]=[N-])[C@@H](O)[C@@H](O)[C@@H]2O |r,@:6| Show InChI InChI=1S/C16H29N5O5/c17-20-19-9-7-5-3-1-2-4-6-8-18-15-14(24)13(23)12(22)11-10-26-16(25)21(11)15/h11-15,18,22-24H,1-10H2/t11-,12-,13+,14+,15+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sevilla Curated by ChEMBL					Assay Description Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis				J Med Chem 62: 5832-5843 (2019) Article DOI: 10.1021/acs.jmedchem.9b00153 BindingDB Entry DOI: 10.7270/Q22R3W4H
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