BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] A' and Ligand = 'BDBM50236898'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of MAO A				J Med Chem 54: 8236-50 (2011) Article DOI: 10.1021/jm201048w BindingDB Entry DOI: 10.7270/Q2D50NFR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64.6	n/a	n/a	n/a	n/a	n/a	25
China Pharmaceutical University					Assay Description The MAO-A and MAO-B screening biochemical assay was completed by Reaction Biology Corp. with the same assay format with LSD1 assay, and the detailed ...				Chem Biol Drug Des 85: 659-71 (2015) Article DOI: 10.1111/cbdd.12461 BindingDB Entry DOI: 10.7270/Q2GF0S73
China Pharmaceutical University					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of rat MAO-A using serotonin as substrate incubated for 1 hr				J Med Chem 59: 253-63 (2016) Article DOI: 10.1021/acs.jmedchem.5b01361 BindingDB Entry DOI: 10.7270/Q23J3FSW
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of MAO-A (unknown origin) using beetle luciferin derived luminogenic substrate preincubated for 15 mins followed by substrate addition mea...				Eur J Med Chem 144: 52-67 (2018) Article DOI: 10.1016/j.ejmech.2017.12.001 BindingDB Entry DOI: 10.7270/Q20V8GGB
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...				J Med Chem 59: 1531-44 (2016) Article DOI: 10.1021/acs.jmedchem.5b01323 BindingDB Entry DOI: 10.7270/Q2JH3P22
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of MAOA (unknown origin) by luminiscent assay				Medchemcomm 5: 1863-1870 (2014) Article DOI: 10.1039/c4md00283k BindingDB Entry DOI: 10.7270/Q2Q81H3T
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02156 BindingDB Entry DOI: 10.7270/Q2154N4T
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50236898 ((1S,2R)-(+)-2-phenylcyclopropylamine \| CHEMBL25799...) Show SMILES N[C@H]1C[C@@H]1c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Münster Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				Bioorg Med Chem 16: 7148-66 (2008) Article DOI: 10.1016/j.bmc.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CN73QW
Universität Münster Curated by ChEMBL					More data for this Ligand-Target Pair