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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM50202472'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM50202472
PNG
(CHEMBL3927809)
Show SMILES CC(C)Cc1ccc(cc1)C(C)c1nc2cc(OCC=C)ccc2n1Cc1ccccc1C(F)(F)F
Show InChI InChI=1S/C30H31F3N2O/c1-5-16-36-25-14-15-28-27(18-25)34-29(21(4)23-12-10-22(11-13-23)17-20(2)3)35(28)19-24-8-6-7-9-26(24)30(31,32)33/h5-15,18,20-21H,1,16-17,19H2,2-4H3
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n/an/a 170n/an/an/an/an/an/a



Gazi University

Curated by ChEMBL


Assay Description
Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...

Eur J Med Chem 122: 510-519 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.004
BindingDB Entry DOI: 10.7270/Q2H41TCW
More data for this
Ligand-Target Pair