BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Arginase-2, mitochondrial' and Ligand = 'BDBM50350311'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50350311 (CHEMBL1812661) Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human Arg2 at pH 7.5				Citation and Details Article DOI: 10.1016/j.bmc.2020.115658 BindingDB Entry DOI: 10.7270/Q2WS8XZC
TBA					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50350311 (CHEMBL1812661) Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University Curated by ChEMBL					Assay Description Binding affinity to human arginase 2				J Med Chem 54: 5432-43 (2011) Article DOI: 10.1021/jm200443b BindingDB Entry DOI: 10.7270/Q2TH8N21
Drexel University Curated by ChEMBL					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50350311 (CHEMBL1812661) Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars		n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50350311 (CHEMBL1812661) Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery Curated by ChEMBL					Assay Description Inhibition of human Arg2 by colorimetric assay				Bioorg Med Chem Lett 23: 2027-30 (2013) Article DOI: 10.1016/j.bmcl.2013.02.024 BindingDB Entry DOI: 10.7270/Q22J6D8K
Institutes for Pharmaceutical Discovery Curated by ChEMBL					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50350311 (CHEMBL1812661) Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars		n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM50350311 (CHEMBL1812661) Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery Curated by ChEMBL					Assay Description Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
Institutes for Pharmaceutical Discovery Curated by ChEMBL					More data for this Ligand-Target Pair