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Found 2 hits Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1 [30-579]' and Ligand = 'BDBM359728'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM359728
PNG
(US10435355, Example 12 | US9822068, 12 | [3-(3-car...)
Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.230n/an/an/an/an/an/a



The Regents of the University of California

US Patent


Assay Description
Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...


US Patent US10435355 (2019)


BindingDB Entry DOI: 10.7270/Q29C70TM
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM359728
PNG
(US10435355, Example 12 | US9822068, 12 | [3-(3-car...)
Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.230n/an/an/an/an/an/a



The Regents of the University of California; Fondazione Istituto Italiano di Technologia

US Patent


Assay Description
Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...


US Patent US9822068 (2017)


BindingDB Entry DOI: 10.7270/Q2Q242HW
More data for this
Ligand-Target Pair