BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 4' and Ligand = 'BDBM50044849'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Free fatty acid receptor 4 (Mus musculus)	BDBM50044849 (CHEMBL3311308) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at mouse FFA4 receptor in mouse MIN6 cells assessed as induction of glucose-induced insulin secretion by AlphaLISA				Bioorg Med Chem Lett 24: 3100-3 (2014) Article DOI: 10.1016/j.bmcl.2014.05.012 BindingDB Entry DOI: 10.7270/Q2CC1292
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Rattus norvegicus)	BDBM50044849 (CHEMBL3311308) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at rat FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR				Bioorg Med Chem Lett 24: 3100-3 (2014) Article DOI: 10.1016/j.bmcl.2014.05.012 BindingDB Entry DOI: 10.7270/Q2CC1292
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50044849 (CHEMBL3311308) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interacti...				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
University of Southern Denmark Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50044849 (CHEMBL3311308) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	501	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR				Bioorg Med Chem Lett 24: 3100-3 (2014) Article DOI: 10.1016/j.bmcl.2014.05.012 BindingDB Entry DOI: 10.7270/Q2CC1292
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Mus musculus)	BDBM50044849 (CHEMBL3311308) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at mouse FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR				Bioorg Med Chem Lett 24: 3100-3 (2014) Article DOI: 10.1016/j.bmcl.2014.05.012 BindingDB Entry DOI: 10.7270/Q2CC1292
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair