Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
L-lactate dehydrogenase (Plasmodium falciparum) | BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | DrugBank PDB Article PubMed | n/a | n/a | 9.25E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
University of Mississippi | Assay Description LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia... | J Med Chem 50: 3841-50 (2007) Article DOI: 10.1021/jm070336k BindingDB Entry DOI: 10.7270/Q2HH6HCV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
L-lactate dehydrogenase (Plasmodium falciparum) | BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | n/a | n/a | 9.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi | Assay Description Enzyme assay using recombinant pfLDH and mLDH (bovine heart). | J Comb Chem 9: 292-300 (2007) Article DOI: 10.1021/cc060110n BindingDB Entry DOI: 10.7270/Q23J3BKZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
L-lactate dehydrogenase (Bos taurus (Bovine)) | BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.16E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi | Assay Description Enzyme assay using recombinant pfLDH and mLDH (bovine heart). | J Comb Chem 9: 292-300 (2007) Article DOI: 10.1021/cc060110n BindingDB Entry DOI: 10.7270/Q23J3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase (Plasmodium falciparum) | BDBM23222 (Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi | Assay Description MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa... | J Med Chem 50: 3841-50 (2007) Article DOI: 10.1021/jm070336k BindingDB Entry DOI: 10.7270/Q2HH6HCV | |||||||||||
More data for this Ligand-Target Pair |