Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assay | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112470 BindingDB Entry DOI: 10.7270/Q2QN6BJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Marine Science and Technology Curated by ChEMBL | Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay | Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL | Assay Description Inhibition of c-Kit (unknown origin) using biotinylated-poly(Glu, Tyr)4:1 as substrate preincubated for 60 mins followed by substrate addition measur... | Eur J Med Chem 123: 431-446 (2016) Article DOI: 10.1016/j.ejmech.2016.07.059 BindingDB Entry DOI: 10.7270/Q2KK9DR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of c-Kit (unknown origin) | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112241 BindingDB Entry DOI: 10.7270/Q21R6V5C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL | Assay Description Inhibition of c-KIT (unknown origin) | Eur J Med Chem 87: 508-18 (2014) Article DOI: 10.1016/j.ejmech.2014.09.095 BindingDB Entry DOI: 10.7270/Q24X59KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL | Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay | Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
St. John's University Curated by ChEMBL | Assay Description Inhibition of KIT (unknown origin) preincubated for 60 mins followed by biotinylated-poly (Glu, Tyr) 4:1 substrate addition measured after 1 hr by Al... | J Med Chem 59: 8712-8756 (2016) Article DOI: 10.1021/acs.jmedchem.6b00472 BindingDB Entry DOI: 10.7270/Q29G5PR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China; College of Pharma Curated by ChEMBL | Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay | Bioorg Med Chem 25: 4475-4486 (2017) Article DOI: 10.1016/j.bmc.2017.06.037 BindingDB Entry DOI: 10.7270/Q2PC34W2 | |||||||||||
More data for this Ligand-Target Pair |