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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-S-isoprenylcysteine O-methyltransferase' and Ligand = 'BDBM50348022'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-S-isoprenylcysteine O-methyltransferase


(Homo sapiens (Human))		BDBM50348022
PNG
(CHEMBL1800419)
Show SMILES Cc1ccc(NCCC2(CCOC(C)(C)C2)c2ccccc2)cc1C
Show InChI InChI=1S/C23H31NO/c1-18-10-11-21(16-19(18)2)24-14-12-23(20-8-6-5-7-9-20)13-15-25-22(3,4)17-23/h5-11,16,24H,12-15,17H2,1-4H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 69n/an/an/an/an/an/a



Myrexis, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant C-terminal His6-tagged ICMT assessed as methylation of N-acetyl-S-geranylgeranylcysteine using SAM as methyl donor su...

J Med Chem 54: 5031-47 (2011)


Article DOI: 10.1021/jm200249a
BindingDB Entry DOI: 10.7270/Q2XW4K49
More data for this
Ligand-Target Pair