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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50047088'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50047088
PNG
(2-{2-[4-(3H-Inden-1-ylmethyl)-piperidin-1-yl]-ethy...)
Show SMILES O=S1(=O)N(CCN2CCC(CC3=CCc4ccccc34)CC2)c2cccc3cccc1c23 |t:11|
Show InChI InChI=1S/C27H28N2O2S/c30-32(31)26-10-4-7-22-6-3-9-25(27(22)26)29(32)18-17-28-15-13-20(14-16-28)19-23-12-11-21-5-1-2-8-24(21)23/h1-10,12,20H,11,13-19H2
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 5n/an/an/an/an/an/a



Centre de Recherches de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptake

J Med Chem 36: 1194-202 (1993)


BindingDB Entry DOI: 10.7270/Q2MC8Z3Z
More data for this
Ligand-Target Pair