Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50263516 (CHEMBL450092 | N4-(6-(2-(2-chloro-6-methylphenylam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL | Assay Description Inhibition of TEL fused Lck (unknown origin)-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase as... | Bioorg Med Chem Lett 18: 5618-21 (2008) Article DOI: 10.1016/j.bmcl.2008.08.104 BindingDB Entry DOI: 10.7270/Q2DN44WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50263516 (CHEMBL450092 | N4-(6-(2-(2-chloro-6-methylphenylam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL | Assay Description Inhibition of TEL fused Lck (unknown origin)-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase as... | Bioorg Med Chem Lett 18: 5618-21 (2008) Article DOI: 10.1016/j.bmcl.2008.08.104 BindingDB Entry DOI: 10.7270/Q2DN44WQ | |||||||||||
More data for this Ligand-Target Pair |