Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1 [1-322]' and Ligand = 'BDBM50166435'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 [1-322] (Homo sapiens (Human))	BDBM50166435 (5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...) Show SMILES COc1ccc(cc1N1CC(=O)NS1(=O)=O)-c1ccccc1 Show InChI InChI=1S/C15H14N2O4S/c1-21-14-8-7-12(11-5-3-2-4-6-11)9-13(14)17-10-15(18)16-22(17,19)20/h2-9H,10H2,1H3,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	2.40E+3	n/a	4.80E+3	n/a	n/a	n/a	n/a	7.0	n/a
University of Missouri					Assay Description Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...				Biochemistry 56: 2051-2060 (2017) Article DOI: 10.1021/acs.biochem.7b00151 BindingDB Entry DOI: 10.7270/Q2HX1BJ8
					More data for this Ligand-Target Pair				3D Structure (crystal)