Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'VHL complex' and Ligand = 'BDBM454866'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VHL complex (Homo sapiens (Human))	BDBM454866 (US10730870, Example 29 | US11512083, Example 29) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccc2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C29H34N4O4S/c1-18-24(38-17-31-18)20-12-10-19(11-13-20)15-30-27(36)23-14-22(34)16-33(23)28(37)25(29(2,3)4)32-26(35)21-8-6-5-7-9-21/h5-13,17,22-23,25,34H,14-16H2,1-4H3,(H,30,36)(H,32,35)/t22-,23+,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	905	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454866 (US10730870, Example 29 | US11512083, Example 29) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccc2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C29H34N4O4S/c1-18-24(38-17-31-18)20-12-10-19(11-13-20)15-30-27(36)23-14-22(34)16-33(23)28(37)25(29(2,3)4)32-26(35)21-8-6-5-7-9-21/h5-13,17,22-23,25,34H,14-16H2,1-4H3,(H,30,36)(H,32,35)/t22-,23+,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454866 (US10730870, Example 29 | US11512083, Example 29) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccc2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C29H34N4O4S/c1-18-24(38-17-31-18)20-12-10-19(11-13-20)15-30-27(36)23-14-22(34)16-33(23)28(37)25(29(2,3)4)32-26(35)21-8-6-5-7-9-21/h5-13,17,22-23,25,34H,14-16H2,1-4H3,(H,30,36)(H,32,35)/t22-,23+,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair