Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50425123![]() (CHEMBL2313234 | US9669035, B-3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026827![]() (CHEMBL3331516 | US9669035, B-6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026829![]() (CHEMBL3331514 | US9669035, B-7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026828![]() (CHEMBL3331515 | US9669035, B-8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026826![]() (CHEMBL3331517 | US11419874, Example 9 | US9669035,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026821![]() (CHEMBL3331521 | US11419874, Example 10 | US9669035...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026820![]() (CHEMBL3331513 | US9669035, B-10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026825![]() (CHEMBL3331518 | US9669035, B-12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026824![]() (CHEMBL3331519 | US9669035, B-16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026822![]() (CHEMBL3331522) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50026823![]() (CHEMBL3331520) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 404 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV Curated by ChEMBL | Assay Description Inhibition of human PDE2A expressed in Sf9 cells incubated for 40 mins using [3H]-cGMP substrate by scintillation counting method | ACS Med Chem Lett 5: 1049-53 (2014) Article DOI: 10.1021/ml500262u BindingDB Entry DOI: 10.7270/Q2QN68DN | |||||||||||
More data for this Ligand-Target Pair |