Found 29 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50015620 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158453
![PNG](/data/jpeg/tenK5015/BindingDB_50158453.png) (CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)Show InChI InChI=1S/C12H10F3N3O2S/c13-12(14,15)21(19,20)18-10-6-7-16-8-11(10)17-9-4-2-1-3-5-9/h1-8,17H,(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158450
![PNG](/data/jpeg/tenK5015/BindingDB_50158450.png) (CHEMBL224136 | N-[3-(2,4-dichlorophenoxy)-4-pyridi...)Show InChI InChI=1S/C12H10Cl2N2O3S/c1-20(17,18)16-10-4-5-15-7-12(10)19-11-3-2-8(13)6-9(11)14/h2-7H,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158444
![PNG](/data/jpeg/tenK5015/BindingDB_50158444.png) (CHEMBL388628 | N-(3-(2-chlorophenoxy)-4-pyridinyl)...)Show InChI InChI=1S/C12H11ClN2O3S/c1-19(16,17)15-10-6-7-14-8-12(10)18-11-5-3-2-4-9(11)13/h2-8H,1H3,(H,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158451
![PNG](/data/jpeg/tenK5015/BindingDB_50158451.png) (CHEMBL224640 | N-[3-(2-chlorophenoxy)-4-pyridinyl]...)Show InChI InChI=1S/C12H8ClF3N2O3S/c13-8-3-1-2-4-10(8)21-11-7-17-6-5-9(11)18-22(19,20)12(14,15)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
![PNG](/data/jpeg/tenK1/BindingDB_11639.png) (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158438
![PNG](/data/jpeg/tenK5015/BindingDB_50158438.png) (CHEMBL225092 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...)Show InChI InChI=1S/C13H11F3N2O4S/c1-21-9-2-4-10(5-3-9)22-12-8-17-7-6-11(12)18-23(19,20)13(14,15)16/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158437
![PNG](/data/jpeg/tenK5015/BindingDB_50158437.png) (CHEMBL224612 | N-(3-phenylsulfanyl-4-pyridinyl)tri...)Show InChI InChI=1S/C12H9F3N2O2S2/c13-12(14,15)21(18,19)17-10-6-7-16-8-11(10)20-9-4-2-1-3-5-9/h1-8H,(H,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50120981
![PNG](/data/jpeg/tenK5012/BindingDB_50120981.png) (1,1,1-trifluoro-N-(3-phenoxypyridin-4-yl)methanesu...)Show InChI InChI=1S/C12H9F3N2O3S/c13-12(14,15)21(18,19)17-10-6-7-16-8-11(10)20-9-4-2-1-3-5-9/h1-8H,(H,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50056999
![PNG](/data/jpeg/tenK5005/BindingDB_50056999.png) (CHEMBL56367 | nimesulide)Show InChI InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158452
![PNG](/data/jpeg/tenK5015/BindingDB_50158452.png) (CHEMBL224122 | N-(3-(phenylthio)pyridin-4-yl)metha...)Show InChI InChI=1S/C12H12N2O2S2/c1-18(15,16)14-11-7-8-13-9-12(11)17-10-5-3-2-4-6-10/h2-9H,1H3,(H,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158432
![PNG](/data/jpeg/tenK5015/BindingDB_50158432.png) (CHEMBL225113 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)Show InChI InChI=1S/C12H8ClF3N2O3S/c13-8-1-3-9(4-2-8)21-11-7-17-6-5-10(11)18-22(19,20)12(14,15)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158456
![PNG](/data/jpeg/tenK5015/BindingDB_50158456.png) (CHEMBL388625 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)Show InChI InChI=1S/C12H11ClN2O3S/c1-19(16,17)15-11-6-7-14-8-12(11)18-10-4-2-9(13)3-5-10/h2-8H,1H3,(H,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158435
![PNG](/data/jpeg/tenK5015/BindingDB_50158435.png) (CHEMBL224192 | N-[3-(3-chlorophenoxy)-4-pyridinyl]...)Show InChI InChI=1S/C12H11ClN2O3S/c1-19(16,17)15-11-5-6-14-8-12(11)18-10-4-2-3-9(13)7-10/h2-8H,1H3,(H,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158436
![PNG](/data/jpeg/tenK5015/BindingDB_50158436.png) (CHEMBL224624 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...)Show InChI InChI=1S/C13H14N2O4S/c1-18-10-3-5-11(6-4-10)19-13-9-14-8-7-12(13)15-20(2,16)17/h3-9H,1-2H3,(H,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158440
![PNG](/data/jpeg/tenK5015/BindingDB_50158440.png) (CHEMBL387879 | N-[3-(2,4-dichlorophenoxy)-4-pyridi...)Show InChI InChI=1S/C12H7Cl2F3N2O3S/c13-7-1-2-10(8(14)5-7)22-11-6-18-4-3-9(11)19-23(20,21)12(15,16)17/h1-6H,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158439
![PNG](/data/jpeg/tenK5015/BindingDB_50158439.png) (CHEMBL223655 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)Show InChI InChI=1S/C13H13ClN2O3S/c1-2-20(17,18)16-12-7-8-15-9-13(12)19-11-5-3-10(14)4-6-11/h3-9H,2H2,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158442
![PNG](/data/jpeg/tenK5015/BindingDB_50158442.png) (CHEMBL224193 | N-[3-(4-bromophenoxy)-4-pyridinyl]m...)Show InChI InChI=1S/C12H11BrN2O3S/c1-19(16,17)15-11-6-7-14-8-12(11)18-10-4-2-9(13)3-5-10/h2-8H,1H3,(H,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158447
![PNG](/data/jpeg/tenK5015/BindingDB_50158447.png) (CHEMBL374169 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)Show InChI InChI=1S/C14H15ClN2O3S/c1-2-9-21(18,19)17-13-7-8-16-10-14(13)20-12-5-3-11(15)4-6-12/h3-8,10H,2,9H2,1H3,(H,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158443
![PNG](/data/jpeg/tenK5015/BindingDB_50158443.png) (CHEMBL374168 | N-[3-(4-bromophenoxy)-4-pyridinyl]t...)Show InChI InChI=1S/C12H8BrF3N2O3S/c13-8-1-3-9(4-2-8)21-11-7-17-6-5-10(11)18-22(19,20)12(14,15)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158446
![PNG](/data/jpeg/tenK5015/BindingDB_50158446.png) (CHEMBL376143 | N-(3-phenoxy-4-pyridinyl)ethanesulf...)Show InChI InChI=1S/C13H14N2O3S/c1-2-19(16,17)15-12-8-9-14-10-13(12)18-11-6-4-3-5-7-11/h3-10H,2H2,1H3,(H,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158433
![PNG](/data/jpeg/tenK5015/BindingDB_50158433.png) (CHEMBL224401 | N-[3-(N'-methyl-N'-phenylamino)-4-p...)Show InChI InChI=1S/C13H12F3N3O2S/c1-19(10-5-3-2-4-6-10)12-9-17-8-7-11(12)18-22(20,21)13(14,15)16/h2-9H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158455
![PNG](/data/jpeg/tenK5015/BindingDB_50158455.png) (CHEMBL390317 | N-[3-(3,5-dichlorophenoxy)-4-pyridi...)Show InChI InChI=1S/C12H10Cl2N2O3S/c1-20(17,18)16-11-2-3-15-7-12(11)19-10-5-8(13)4-9(14)6-10/h2-7H,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158434
![PNG](/data/jpeg/tenK5015/BindingDB_50158434.png) (CHEMBL224256 | N-(3-phenylsulfonyl-4-pyridinyl)met...)Show InChI InChI=1S/C12H12N2O4S2/c1-19(15,16)14-11-7-8-13-9-12(11)20(17,18)10-5-3-2-4-6-10/h2-9H,1H3,(H,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158454
![PNG](/data/jpeg/tenK5015/BindingDB_50158454.png) (CHEMBL225236 | N-[3-(3,5-dichlorophenoxy)-4-pyridi...)Show SMILES FC(F)(F)S(=O)(=O)Nc1ccncc1Oc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C12H7Cl2F3N2O3S/c13-7-3-8(14)5-9(4-7)22-11-6-18-2-1-10(11)19-23(20,21)12(15,16)17/h1-6H,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158449
![PNG](/data/jpeg/tenK5015/BindingDB_50158449.png) (CHEMBL389485 | N-(3-phenoxy-4-pyridinyl)propanesul...)Show InChI InChI=1S/C14H16N2O3S/c1-2-10-20(17,18)16-13-8-9-15-11-14(13)19-12-6-4-3-5-7-12/h3-9,11H,2,10H2,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158445
![PNG](/data/jpeg/tenK5015/BindingDB_50158445.png) (CHEMBL224781 | N-(3-phenylsulfinyl-4-pyridinyl)tri...)Show InChI InChI=1S/C12H9F3N2O3S2/c13-12(14,15)22(19,20)17-10-6-7-16-8-11(10)21(18)9-4-2-1-3-5-9/h1-8H,(H,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50120980
![PNG](/data/jpeg/tenK5012/BindingDB_50120980.png) (CHEMBL148542 | N-(3-Phenoxy-pyridin-4-yl)-methanes...)Show InChI InChI=1S/C12H12N2O3S/c1-18(15,16)14-11-7-8-13-9-12(11)17-10-5-3-2-4-6-10/h2-9H,1H3,(H,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158448
![PNG](/data/jpeg/tenK5015/BindingDB_50158448.png) (CHEMBL224201 | N-(3-phenylsulfonyl-4-pyridinyl)tri...)Show SMILES FC(F)(F)S(=O)(=O)Nc1ccncc1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C12H9F3N2O4S2/c13-12(14,15)23(20,21)17-10-6-7-16-8-11(10)22(18,19)9-4-2-1-3-5-9/h1-8H,(H,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50158441
![PNG](/data/jpeg/tenK5015/BindingDB_50158441.png) (CHEMBL224693 | N-[3-(3-chlorophenoxy)-4-pyridinyl]...)Show InChI InChI=1S/C12H8ClF3N2O3S/c13-8-2-1-3-9(6-8)21-11-7-17-5-4-10(11)18-22(19,20)12(14,15)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Liège
Curated by ChEMBL
| Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production |
J Med Chem 47: 6749-59 (2004)
Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK |
More data for this Ligand-Target Pair | |