Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50326044 ((2S,5S,8R,11S,14S,17S,20S,23S,26R,29S,32S,35S,38S,...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratory of Molecular Biology, Medical Research Council Curated by ChEMBL | Assay Description Binding affinity to tissue factor/factor 7a | Nat Chem Biol 5: 502-7 (2009) Article DOI: 10.1038/nchembio.184 BindingDB Entry DOI: 10.7270/Q2Z60P9P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172214 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172213 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172227 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172227 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172217 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172212 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172225 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177189 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177187 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM14593 (3-amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Hefei University of Technology Curated by ChEMBL | Assay Description Inhibition of recombinant soluble tissue factor (unknown origin)/recombinant human factor 7a using N-methylsulfonyl-D-phe-gly arg-p-nitroaniline as s... | Eur J Med Chem 146: 299-317 (2018) Article DOI: 10.1016/j.ejmech.2018.01.067 BindingDB Entry DOI: 10.7270/Q2251MTJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172218 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172232 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177200 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172220 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172224 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177185 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172223 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM14543 (2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Hefei University of Technology Curated by ChEMBL | Assay Description Inhibition of recombinant soluble tissue factor (unknown origin)/recombinant human factor 7a using N-methylsulfonyl-D-phe-gly arg-p-nitroaniline as s... | Eur J Med Chem 146: 299-317 (2018) Article DOI: 10.1016/j.ejmech.2018.01.067 BindingDB Entry DOI: 10.7270/Q2251MTJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172211 (5-tert-Butyl-2-[6-(3-carbamimidoyl-phenoxy)-3,5-di...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172209 (4-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172229 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177192 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172208 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177209 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177190 (4-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172235 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172215 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172231 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177196 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172233 (2-{6-[3-amino(imino)methylphenoxy]-3,5-difluoro-4-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172210 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177201 (CHEMBL382807 | N-benzyl-6-[6-(3-carbamimidoyl-phen...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177213 (4-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM14497 (2-Pyridone 14b | N-[(4-carbamimidoylphenyl)methyl]...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of recombinant human Tissue factor/factor 7a using N-methylsulfonyl-D-phe-gly-arg-p-nitroaniline as substrate assessed as release of p-nit... | J Med Chem 58: 8315-59 (2015) Article DOI: 10.1021/acs.jmedchem.5b00258 BindingDB Entry DOI: 10.7270/Q22J6DPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM14497 (2-Pyridone 14b | N-[(4-carbamimidoylphenyl)methyl]...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Hefei University of Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human soluble tissue factor (1 to 219 residues) expressed in Escherichia coli/recombinant human factor 7a using N-methylsul... | Eur J Med Chem 146: 299-317 (2018) Article DOI: 10.1016/j.ejmech.2018.01.067 BindingDB Entry DOI: 10.7270/Q2251MTJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50594994 (CHEMBL5193093) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114199 BindingDB Entry DOI: 10.7270/Q2CN77X7 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177212 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177193 (2-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172221 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172237 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177214 (5-benzyl-2-[6-(3-carbamimidoyl-phenoxy)-4-diisopro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172226 (5-Amino-2-[6-(3-carbamimidoyl-phenoxy)-3,5-difluor...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50172230 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes | Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM31459 (CHEMBL224485 | substituted biphenyl derivative, 21) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human TF/FVIIa complex by chromogenic assay | Bioorg Med Chem 15: 160-73 (2006) Article DOI: 10.1016/j.bmc.2006.09.071 BindingDB Entry DOI: 10.7270/Q2MG7P56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177215 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50462135 (CHEMBL1230094) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Inhibition of human TF/F7a using spectrozyme f7a as substrate | J Med Chem 61: 3799-3822 (2018) Article DOI: 10.1021/acs.jmedchem.7b00772 BindingDB Entry DOI: 10.7270/Q2C2502H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177203 (2-[6-(3-Carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50177194 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human recombinant FVIIa/TF complex | Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/Tissue factor (Homo sapiens (Human)) | BDBM50594993 (CHEMBL5190859) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114199 BindingDB Entry DOI: 10.7270/Q2CN77X7 | ||||||||||||
More data for this Ligand-Target Pair |
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