Compile Data Set for Download or QSAR

Found 105 hits of ic50 for UniProtKB: P13726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50326044 ((2S,5S,8R,11S,14S,17S,20S,23S,26R,29S,32S,35S,38S,...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCC(O)=O)C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:44.46,78.83,8.8,98.103,21.33,57.58,114.119,77.80,129.134,wD:84.87,4.4,107.112,35.42,108.115,120.125,63.64,12.17,(10.8,-38.91,;10.78,-37.37,;12.1,-36.58,;9.43,-36.62,;9.4,-35.08,;8.05,-34.35,;6.73,-35.14,;6.75,-36.68,;5.38,-34.39,;4.06,-35.18,;2.73,-34.41,;2.7,-32.87,;1.4,-35.2,;1.43,-36.74,;2.78,-37.49,;2.8,-39.03,;1.45,-39.83,;4.15,-39.78,;.06,-34.45,;-1.27,-35.24,;-1.24,-36.78,;-2.61,-34.49,;-2.64,-32.95,;-1.41,-32.02,;-.16,-32.92,;1.07,-32,;.59,-30.54,;1.35,-29.19,;.57,-27.87,;-.98,-27.88,;-1.73,-29.22,;-.95,-30.55,;-3.93,-35.29,;-5.27,-34.53,;-5.3,-32.99,;-6.6,-35.32,;-6.57,-36.86,;-5.22,-37.61,;-5.2,-39.14,;-6.53,-39.94,;-3.86,-39.9,;-7.95,-34.58,;-9.27,-35.37,;-9.25,-36.91,;-10.62,-34.62,;-11.94,-35.41,;-10.64,-33.08,;-9.32,-32.29,;-9.34,-30.75,;-10.69,-30,;-8.02,-29.96,;5.36,-32.85,;6.68,-32.05,;4.02,-32.1,;10.73,-34.29,;10.7,-32.75,;12.07,-35.05,;13.39,-34.26,;13.37,-32.72,;14.69,-31.93,;14.74,-35.01,;14.76,-36.55,;16.05,-34.22,;17.4,-34.95,;17.43,-36.5,;18.67,-37.41,;19.89,-36.48,;21.16,-37.36,;20.71,-38.84,;21.51,-40.15,;20.77,-41.5,;19.23,-41.53,;18.43,-40.22,;19.18,-38.86,;18.73,-34.17,;18.71,-32.63,;20.08,-34.92,;21.4,-34.12,;21.38,-32.58,;20.03,-31.83,;22.66,-31.81,;22.74,-34.87,;22.77,-36.41,;24.06,-34.07,;25.41,-34.81,;25.43,-36.35,;26.69,-37.24,;27.94,-36.36,;29.17,-37.28,;28.67,-38.74,;29.42,-40.09,;28.63,-41.41,;27.09,-41.39,;26.34,-40.03,;27.14,-38.72,;26.73,-34.01,;26.71,-32.47,;28.06,-34.79,;29.38,-33.99,;29.36,-32.45,;30.68,-31.66,;30.66,-30.12,;29.29,-29.38,;31.98,-29.33,;30.73,-34.74,;30.76,-36.28,;32.05,-33.95,;33.41,-34.68,;33.43,-36.22,;32.11,-37.02,;34.75,-36.98,;34.73,-33.89,;34.71,-32.35,;36.06,-34.66,;37.38,-33.86,;37.36,-32.33,;38.68,-31.53,;38.73,-34.61,;38.76,-36.15,;40.05,-33.82,;41.4,-34.56,;41.43,-36.1,;42.78,-36.86,;42.8,-38.4,;41.46,-39.18,;44.14,-39.14,;42.73,-33.78,;42.7,-32.24,;44.07,-34.52,;45.39,-33.73,;45.37,-32.19,;46.7,-31.4,;46.67,-29.86,;47.99,-29.07,;47.97,-27.53,;46.61,-26.78,;49.29,-26.74,;46.74,-34.48,;48.06,-33.69,;46.77,-36.02,)| Show InChI InChI=1S/C89H123N21O28S2/c1-41(2)32-60(104-85(134)71(42(3)4)108-77(126)57(24-29-69(119)120)98-80(129)61(33-45-36-94-52-17-10-7-14-48(45)52)102-76(125)55(22-27-67(115)116)97-74(123)51(90)21-26-66(113)114)79(128)106-64(39-139)84(133)103-63(35-47-38-96-54-19-12-9-16-50(47)54)82(131)110-72(43(5)111)86(135)105-62(34-46-37-95-53-18-11-8-15-49(46)53)81(130)99-58(25-30-70(121)122)78(127)109-73(44(6)112)87(136)107-65(40-140)83(132)100-56(23-28-68(117)118)75(124)101-59(88(137)138)20-13-31-93-89(91)92/h7-12,14-19,36-38,41-44,51,55-65,71-73,94-96,111-112,139-140H,13,20-35,39-40,90H2,1-6H3,(H,97,123)(H,98,129)(H,99,130)(H,100,132)(H,101,124)(H,102,125)(H,103,133)(H,104,134)(H,105,135)(H,106,128)(H,107,136)(H,108,126)(H,109,127)(H,110,131)(H,113,114)(H,115,116)(H,117,118)(H,119,120)(H,121,122)(H,137,138)(H4,91,92,93)/t43-,44-,51+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,71+,72+,73+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratory of Molecular Biology, Medical Research Council Curated by ChEMBL					Assay Description Binding affinity to tissue factor/factor 7a				Nat Chem Biol 5: 502-7 (2009) Article DOI: 10.1038/nchembio.184 BindingDB Entry DOI: 10.7270/Q2Z60P9P
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172214 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES COc1cccc(CNC(=O)c2ccc(Oc3nc(Oc4cccc(c4)C(N)=N)c(F)c(NC(C)CCc4ccccc4)c3F)c(c2)C(O)=O)c1 Show InChI InChI=1S/C38H35F2N5O6/c1-22(14-15-23-8-4-3-5-9-23)44-33-31(39)36(50-28-13-7-11-25(19-28)34(41)42)45-37(32(33)40)51-30-17-16-26(20-29(30)38(47)48)35(46)43-21-24-10-6-12-27(18-24)49-2/h3-13,16-20,22H,14-15,21H2,1-2H3,(H3,41,42)(H,43,46)(H,44,45)(H,47,48)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172213 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(C)CNC(=O)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C34H35F2N5O5/c1-19(2)18-39-31(42)23-14-15-26(25(17-23)34(43)44)46-33-28(36)29(40-20(3)12-13-21-8-5-4-6-9-21)27(35)32(41-33)45-24-11-7-10-22(16-24)30(37)38/h4-11,14-17,19-20H,12-13,18H2,1-3H3,(H3,37,38)(H,39,42)(H,40,41)(H,43,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172227 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)N(C)C)c1F Show InChI InChI=1S/C31H31F2N5O4/c1-18(12-13-19-8-5-4-6-9-19)36-27-25(32)29(41-22-11-7-10-20(16-22)28(34)35)37-30(26(27)33)42-24-15-14-21(38(2)3)17-23(24)31(39)40/h4-11,14-18H,12-13H2,1-3H3,(H3,34,35)(H,36,37)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172227 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)N(C)C)c1F Show InChI InChI=1S/C31H31F2N5O4/c1-18(12-13-19-8-5-4-6-9-19)36-27-25(32)29(41-22-11-7-10-20(16-22)28(34)35)37-30(26(27)33)42-24-15-14-21(38(2)3)17-23(24)31(39)40/h4-11,14-18H,12-13H2,1-3H3,(H3,34,35)(H,36,37)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172217 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC(C)C(C)(C)C)c1F Show InChI InChI=1S/C36H39F2N5O5/c1-20(14-15-22-10-7-6-8-11-22)41-30-28(37)33(47-25-13-9-12-23(18-25)31(39)40)43-34(29(30)38)48-27-17-16-24(19-26(27)35(45)46)32(44)42-21(2)36(3,4)5/h6-13,16-21H,14-15H2,1-5H3,(H3,39,40)(H,41,43)(H,42,44)(H,45,46)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172212 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(C)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C32H32F2N4O4/c1-18(2)21-14-15-25(24(17-21)32(39)40)42-31-27(34)28(37-19(3)12-13-20-8-5-4-6-9-20)26(33)30(38-31)41-23-11-7-10-22(16-23)29(35)36/h4-11,14-19H,12-13H2,1-3H3,(H3,35,36)(H,37,38)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172225 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CCN(CC)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C33H35F2N5O4/c1-4-40(5-2)23-16-17-26(25(19-23)33(41)42)44-32-28(35)29(38-20(3)14-15-21-10-7-6-8-11-21)27(34)31(39-32)43-24-13-9-12-22(18-24)30(36)37/h6-13,16-20H,4-5,14-15H2,1-3H3,(H3,36,37)(H,38,39)(H,41,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177189 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC(C)C(C)(C)C)c1F Show InChI InChI=1S/C32H39F2N5O5/c1-16(2)39(17(3)4)26-24(33)29(43-21-11-9-10-19(14-21)27(35)36)38-30(25(26)34)44-23-13-12-20(15-22(23)31(41)42)28(40)37-18(5)32(6,7)8/h9-18H,1-8H3,(H3,35,36)(H,37,40)(H,41,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177187 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2ccc(Cl)cc2)c1F Show InChI InChI=1S/C33H32ClF2N5O5/c1-17(2)41(18(3)4)28-26(35)31(45-23-7-5-6-20(14-23)29(37)38)40-32(27(28)36)46-25-13-10-21(15-24(25)33(43)44)30(42)39-16-19-8-11-22(34)12-9-19/h5-15,17-18H,16H2,1-4H3,(H3,37,38)(H,39,42)(H,43,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM14593 (3-amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carb...) Show SMILES CC(C)Nc1nc(Cl)c(-c2cc(N)cc(c2)C(O)=O)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C24H26ClN7O4/c1-12(2)30-22-23(34)32(11-18(33)29-10-13-3-5-14(6-4-13)21(27)28)19(20(25)31-22)15-7-16(24(35)36)9-17(26)8-15/h3-9,12H,10-11,26H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Hefei University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant soluble tissue factor (unknown origin)/recombinant human factor 7a using N-methylsulfonyl-D-phe-gly arg-p-nitroaniline as s...				Eur J Med Chem 146: 299-317 (2018) Article DOI: 10.1016/j.ejmech.2018.01.067 BindingDB Entry DOI: 10.7270/Q2251MTJ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172218 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC(C)(C)CO)c1F Show InChI InChI=1S/C34H35F2N5O6/c1-19(12-13-20-8-5-4-6-9-20)39-28-26(35)31(46-23-11-7-10-21(16-23)29(37)38)40-32(27(28)36)47-25-15-14-22(17-24(25)33(44)45)30(43)41-34(2,3)18-42/h4-11,14-17,19,42H,12-13,18H2,1-3H3,(H3,37,38)(H,39,40)(H,41,43)(H,44,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172232 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CNc1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C30H29F2N5O4/c1-17(11-12-18-7-4-3-5-8-18)36-26-24(31)28(40-21-10-6-9-19(15-21)27(33)34)37-29(25(26)32)41-23-14-13-20(35-2)16-22(23)30(38)39/h3-10,13-17,35H,11-12H2,1-2H3,(H3,33,34)(H,36,37)(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177200 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES COc1cccc(CNC(=O)c2ccc(Oc3nc(Oc4cccc(c4)C(N)=N)c(F)c(N(C(C)C)C(C)C)c3F)c(c2)C(O)=O)c1 Show InChI InChI=1S/C34H35F2N5O6/c1-18(2)41(19(3)4)29-27(35)32(46-24-11-7-9-21(15-24)30(37)38)40-33(28(29)36)47-26-13-12-22(16-25(26)34(43)44)31(42)39-17-20-8-6-10-23(14-20)45-5/h6-16,18-19H,17H2,1-5H3,(H3,37,38)(H,39,42)(H,43,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172220 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(C)Oc1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C32H32F2N4O5/c1-18(2)41-23-14-15-25(24(17-23)32(39)40)43-31-27(34)28(37-19(3)12-13-20-8-5-4-6-9-20)26(33)30(38-31)42-22-11-7-10-21(16-22)29(35)36/h4-11,14-19H,12-13H2,1-3H3,(H3,35,36)(H,37,38)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172224 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CCCOc1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C32H32F2N4O5/c1-3-16-41-22-14-15-25(24(18-22)32(39)40)43-31-27(34)28(37-19(2)12-13-20-8-5-4-6-9-20)26(33)30(38-31)42-23-11-7-10-21(17-23)29(35)36/h4-11,14-15,17-19H,3,12-13,16H2,1-2H3,(H3,35,36)(H,37,38)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177185 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)CNC(=O)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(N(C(C)C)C(C)C)c2F)c(c1)C(O)=O Show InChI InChI=1S/C30H35F2N5O5/c1-15(2)14-35-27(38)19-10-11-22(21(13-19)30(39)40)42-29-24(32)25(37(16(3)4)17(5)6)23(31)28(36-29)41-20-9-7-8-18(12-20)26(33)34/h7-13,15-17H,14H2,1-6H3,(H3,33,34)(H,35,38)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172223 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(C)cc2C(O)=O)c1F Show InChI InChI=1S/C30H28F2N4O4/c1-17-11-14-23(22(15-17)30(37)38)40-29-25(32)26(35-18(2)12-13-19-7-4-3-5-8-19)24(31)28(36-29)39-21-10-6-9-20(16-21)27(33)34/h3-11,14-16,18H,12-13H2,1-2H3,(H3,33,34)(H,35,36)(H,37,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM14543 (2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2cccc(N)c2)cc1 Show InChI InChI=1S/C24H26ClN7O2/c25-21-20(16-3-1-4-17(26)11-16)32(24(34)23(31-21)30-18-5-2-6-18)13-19(33)29-12-14-7-9-15(10-8-14)22(27)28/h1,3-4,7-11,18H,2,5-6,12-13,26H2,(H3,27,28)(H,29,33)(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hefei University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant soluble tissue factor (unknown origin)/recombinant human factor 7a using N-methylsulfonyl-D-phe-gly arg-p-nitroaniline as s...				Eur J Med Chem 146: 299-317 (2018) Article DOI: 10.1016/j.ejmech.2018.01.067 BindingDB Entry DOI: 10.7270/Q2251MTJ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172211 (5-tert-Butyl-2-[6-(3-carbamimidoyl-phenoxy)-3,5-di...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(C)(C)C)c1F Show InChI InChI=1S/C33H34F2N4O4/c1-19(13-14-20-9-6-5-7-10-20)38-28-26(34)30(42-23-12-8-11-21(17-23)29(36)37)39-31(27(28)35)43-25-16-15-22(33(2,3)4)18-24(25)32(40)41/h5-12,15-19H,13-14H2,1-4H3,(H3,36,37)(H,38,39)(H,40,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172209 (4-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2ccccc2)c1F Show InChI InChI=1S/C35H30F2N4O4/c1-21(15-16-22-9-4-2-5-10-22)40-31-29(36)33(44-26-14-8-13-25(19-26)32(38)39)41-34(30(31)37)45-28-18-17-24(20-27(28)35(42)43)23-11-6-3-7-12-23/h2-14,17-21H,15-16H2,1H3,(H3,38,39)(H,40,41)(H,42,43)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172229 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CCC(CO)NC(=O)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C34H35F2N5O6/c1-3-23(18-42)40-31(43)22-14-15-26(25(17-22)34(44)45)47-33-28(36)29(39-19(2)12-13-20-8-5-4-6-9-20)27(35)32(41-33)46-24-11-7-10-21(16-24)30(37)38/h4-11,14-17,19,23,42H,3,12-13,18H2,1-2H3,(H3,37,38)(H,39,41)(H,40,43)(H,44,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177192 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2ccc(C)cc2C)c1F Show InChI InChI=1S/C35H37F2N5O5/c1-18(2)42(19(3)4)30-28(36)33(46-25-9-7-8-22(15-25)31(38)39)41-34(29(30)37)47-27-13-12-23(16-26(27)35(44)45)32(43)40-17-24-11-10-20(5)14-21(24)6/h7-16,18-19H,17H2,1-6H3,(H3,38,39)(H,40,43)(H,44,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172208 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CCOc1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C31H30F2N4O5/c1-3-40-21-14-15-24(23(17-21)31(38)39)42-30-26(33)27(36-18(2)12-13-19-8-5-4-6-9-19)25(32)29(37-30)41-22-11-7-10-20(16-22)28(34)35/h4-11,14-18H,3,12-13H2,1-2H3,(H3,34,35)(H,36,37)(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177209 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2c(C)cccc2C)c1F Show InChI InChI=1S/C35H37F2N5O5/c1-18(2)42(19(3)4)30-28(36)33(46-24-12-8-11-22(15-24)31(38)39)41-34(29(30)37)47-27-14-13-23(16-25(27)35(44)45)32(43)40-17-26-20(5)9-7-10-21(26)6/h7-16,18-19H,17H2,1-6H3,(H3,38,39)(H,40,43)(H,44,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177190 (4-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2ccccc2)c1F Show InChI InChI=1S/C31H30F2N4O4/c1-17(2)37(18(3)4)27-25(32)29(40-22-12-8-11-21(15-22)28(34)35)36-30(26(27)33)41-24-14-13-20(16-23(24)31(38)39)19-9-6-5-7-10-19/h5-18H,1-4H3,(H3,34,35)(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172235 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CCCCN(CCCC)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C37H43F2N5O4/c1-4-6-20-44(21-7-5-2)27-18-19-30(29(23-27)37(45)46)48-36-32(39)33(42-24(3)16-17-25-12-9-8-10-13-25)31(38)35(43-36)47-28-15-11-14-26(22-28)34(40)41/h8-15,18-19,22-24H,4-7,16-17,20-21H2,1-3H3,(H3,40,41)(H,42,43)(H,45,46)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172215 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2cccc(O)c2)c1F Show InChI InChI=1S/C37H33F2N5O6/c1-21(13-14-22-7-3-2-4-8-22)43-32-30(38)35(49-27-12-6-10-24(18-27)33(40)41)44-36(31(32)39)50-29-16-15-25(19-28(29)37(47)48)34(46)42-20-23-9-5-11-26(45)17-23/h2-12,15-19,21,45H,13-14,20H2,1H3,(H3,40,41)(H,42,46)(H,43,44)(H,47,48)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172231 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES COc1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C30H28F2N4O5/c1-17(11-12-18-7-4-3-5-8-18)35-26-24(31)28(40-21-10-6-9-19(15-21)27(33)34)36-29(25(26)32)41-23-14-13-20(39-2)16-22(23)30(37)38/h3-10,13-17H,11-12H2,1-2H3,(H3,33,34)(H,35,36)(H,37,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177196 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC2CCCC2)c1F Show InChI InChI=1S/C31H35F2N5O5/c1-16(2)38(17(3)4)26-24(32)29(42-21-11-7-8-18(14-21)27(34)35)37-30(25(26)33)43-23-13-12-19(15-22(23)31(40)41)28(39)36-20-9-5-6-10-20/h7-8,11-17,20H,5-6,9-10H2,1-4H3,(H3,34,35)(H,36,39)(H,40,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172233 (2-{6-[3-amino(imino)methylphenoxy]-3,5-difluoro-4-...) Show SMILES C[C@H](CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=[NH2+])nc(Oc2ccccc2C([O-])=O)c1F Show InChI InChI=1S/C29H26F2N4O4/c1-17(14-15-18-8-3-2-4-9-18)34-25-23(30)27(38-20-11-7-10-19(16-20)26(32)33)35-28(24(25)31)39-22-13-6-5-12-21(22)29(36)37/h2-13,16-17H,14-15H2,1H3,(H3,32,33)(H,34,35)(H,36,37)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172210 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC(CO)CO)c1F Show InChI InChI=1S/C33H33F2N5O7/c1-18(10-11-19-6-3-2-4-7-19)38-28-26(34)31(46-23-9-5-8-20(14-23)29(36)37)40-32(27(28)35)47-25-13-12-21(15-24(25)33(44)45)30(43)39-22(16-41)17-42/h2-9,12-15,18,22,41-42H,10-11,16-17H2,1H3,(H3,36,37)(H,38,40)(H,39,43)(H,44,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177201 (CHEMBL382807 | N-benzyl-6-[6-(3-carbamimidoyl-phen...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2ccccc2)c1F Show InChI InChI=1S/C33H33F2N5O5/c1-18(2)40(19(3)4)28-26(34)31(44-23-12-8-11-21(15-23)29(36)37)39-32(27(28)35)45-25-14-13-22(16-24(25)33(42)43)30(41)38-17-20-9-6-5-7-10-20/h5-16,18-19H,17H2,1-4H3,(H3,36,37)(H,38,41)(H,42,43)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177213 (4-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2cccc(C)c2)c1F Show InChI InChI=1S/C32H32F2N4O4/c1-17(2)38(18(3)4)28-26(33)30(41-23-11-7-10-22(15-23)29(35)36)37-31(27(28)34)42-25-13-12-21(16-24(25)32(39)40)20-9-6-8-19(5)14-20/h6-18H,1-5H3,(H3,35,36)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM14497 (2-Pyridone 14b | N-[(4-carbamimidoylphenyl)methyl]...) Show SMILES CC(C)Nc1ccc(-c2cc(N)cc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C24H29N7O2/c1-14(2)30-20-7-8-21(17-9-18(25)11-19(26)10-17)31(24(20)33)13-22(32)29-12-15-3-5-16(6-4-15)23(27)28/h3-11,14,30H,12-13,25-26H2,1-2H3,(H3,27,28)(H,29,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Tissue factor/factor 7a using N-methylsulfonyl-D-phe-gly-arg-p-nitroaniline as substrate assessed as release of p-nit...				J Med Chem 58: 8315-59 (2015) Article DOI: 10.1021/acs.jmedchem.5b00258 BindingDB Entry DOI: 10.7270/Q22J6DPZ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM14497 (2-Pyridone 14b | N-[(4-carbamimidoylphenyl)methyl]...) Show SMILES CC(C)Nc1ccc(-c2cc(N)cc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C24H29N7O2/c1-14(2)30-20-7-8-21(17-9-18(25)11-19(26)10-17)31(24(20)33)13-22(32)29-12-15-3-5-16(6-4-15)23(27)28/h3-11,14,30H,12-13,25-26H2,1-2H3,(H3,27,28)(H,29,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Hefei University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human soluble tissue factor (1 to 219 residues) expressed in Escherichia coli/recombinant human factor 7a using N-methylsul...				Eur J Med Chem 146: 299-317 (2018) Article DOI: 10.1016/j.ejmech.2018.01.067 BindingDB Entry DOI: 10.7270/Q2251MTJ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50594994 (CHEMBL5193093) Show SMILES CC(C)Nc1ccc(-c2cc(N)cc(c2)[N+]([O-])=O)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114199 BindingDB Entry DOI: 10.7270/Q2CN77X7
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177212 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NC2CCCCC2)c1F Show InChI InChI=1S/C32H37F2N5O5/c1-17(2)39(18(3)4)27-25(33)30(43-22-12-8-9-19(15-22)28(35)36)38-31(26(27)34)44-24-14-13-20(16-23(24)32(41)42)29(40)37-21-10-6-5-7-11-21/h8-9,12-18,21H,5-7,10-11H2,1-4H3,(H3,35,36)(H,37,40)(H,41,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177193 (2-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2ccsc2)c1F Show InChI InChI=1S/C29H28F2N4O4S/c1-15(2)35(16(3)4)25-23(30)27(38-20-7-5-6-18(12-20)26(32)33)34-28(24(25)31)39-22-9-8-17(13-21(22)29(36)37)19-10-11-40-14-19/h5-16H,1-4H3,(H3,32,33)(H,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172221 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCCCCO)c1F Show InChI InChI=1S/C34H35F2N5O6/c1-20(12-13-21-8-3-2-4-9-21)40-29-27(35)32(46-24-11-7-10-22(18-24)30(37)38)41-33(28(29)36)47-26-15-14-23(19-25(26)34(44)45)31(43)39-16-5-6-17-42/h2-4,7-11,14-15,18-20,42H,5-6,12-13,16-17H2,1H3,(H3,37,38)(H,39,43)(H,40,41)(H,44,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172237 (6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCCCO)c1F Show InChI InChI=1S/C33H33F2N5O6/c1-19(11-12-20-7-3-2-4-8-20)39-28-26(34)31(45-23-10-5-9-21(17-23)29(36)37)40-32(27(28)35)46-25-14-13-22(18-24(25)33(43)44)30(42)38-15-6-16-41/h2-5,7-10,13-14,17-19,41H,6,11-12,15-16H2,1H3,(H3,36,37)(H,38,42)(H,39,40)(H,43,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177214 (5-benzyl-2-[6-(3-carbamimidoyl-phenoxy)-4-diisopro...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(Cc3ccccc3)cc2C(O)=O)c1F Show InChI InChI=1S/C32H32F2N4O4/c1-18(2)38(19(3)4)28-26(33)30(41-23-12-8-11-22(17-23)29(35)36)37-31(27(28)34)42-25-14-13-21(16-24(25)32(39)40)15-20-9-6-5-7-10-20/h5-14,16-19H,15H2,1-4H3,(H3,35,36)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172226 (5-Amino-2-[6-(3-carbamimidoyl-phenoxy)-3,5-difluor...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(N)cc2C(O)=O)c1F Show InChI InChI=1S/C29H27F2N5O4/c1-16(10-11-17-6-3-2-4-7-17)35-25-23(30)27(39-20-9-5-8-18(14-20)26(33)34)36-28(24(25)31)40-22-13-12-19(32)15-21(22)29(37)38/h2-9,12-16H,10-11,32H2,1H3,(H3,33,34)(H,35,36)(H,37,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172230 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccccc2C(O)=O)c1F Show InChI InChI=1S/C29H26F2N4O4/c1-17(14-15-18-8-3-2-4-9-18)34-25-23(30)27(38-20-11-7-10-19(16-20)26(32)33)35-28(24(25)31)39-22-13-6-5-12-21(22)29(36)37/h2-13,16-17H,14-15H2,1H3,(H3,32,33)(H,34,35)(H,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM31459 (CHEMBL224485 | substituted biphenyl derivative, 21) Show SMILES CC(C)CNC(=O)c1ccc(c(c1)C(O)=O)-c1ccccc1C(=O)Nc1ccc(cc1)C(N)=N Show InChI InChI=1S/C26H26N4O4/c1-15(2)14-29-24(31)17-9-12-20(22(13-17)26(33)34)19-5-3-4-6-21(19)25(32)30-18-10-7-16(8-11-18)23(27)28/h3-13,15H,14H2,1-2H3,(H3,27,28)(H,29,31)(H,30,32)(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human TF/FVIIa complex by chromogenic assay				Bioorg Med Chem 15: 160-73 (2006) Article DOI: 10.1016/j.bmc.2006.09.071 BindingDB Entry DOI: 10.7270/Q2MG7P56
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177215 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CCCNC(=O)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(N(C(C)C)C(C)C)c2F)c(c1)C(O)=O Show InChI InChI=1S/C29H33F2N5O5/c1-6-12-34-26(37)18-10-11-21(20(14-18)29(38)39)41-28-23(31)24(36(15(2)3)16(4)5)22(30)27(35-28)40-19-9-7-8-17(13-19)25(32)33/h7-11,13-16H,6,12H2,1-5H3,(H3,32,33)(H,34,37)(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50462135 (CHEMBL1230094) Show SMILES CCS(=O)(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C30H36N6O5S/c1-2-42(40,41)36-26(18-20-8-12-23(13-9-20)22-6-4-3-5-7-22)30(39)35-25(16-17-27(31)37)29(38)34-19-21-10-14-24(15-11-21)28(32)33/h3-15,25-26,36H,2,16-19H2,1H3,(H2,31,37)(H3,32,33)(H,34,38)(H,35,39)/t25-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human TF/F7a using spectrozyme f7a as substrate				J Med Chem 61: 3799-3822 (2018) Article DOI: 10.1021/acs.jmedchem.7b00772 BindingDB Entry DOI: 10.7270/Q2C2502H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177203 (2-[6-(3-Carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2ccccn2)c1F Show InChI InChI=1S/C30H29F2N5O4/c1-16(2)37(17(3)4)26-24(31)28(40-20-9-7-8-19(14-20)27(33)34)36-29(25(26)32)41-23-12-11-18(15-21(23)30(38)39)22-10-5-6-13-35-22/h5-17H,1-4H3,(H3,33,34)(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50177194 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CCCCCNC(=O)c1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(N(C(C)C)C(C)C)c2F)c(c1)C(O)=O Show InChI InChI=1S/C31H37F2N5O5/c1-6-7-8-14-36-28(39)20-12-13-23(22(16-20)31(40)41)43-30-25(33)26(38(17(2)3)18(4)5)24(32)29(37-30)42-21-11-9-10-19(15-21)27(34)35/h9-13,15-18H,6-8,14H2,1-5H3,(H3,34,35)(H,36,39)(H,40,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50594993 (CHEMBL5190859) Show SMILES CC(C)Nc1ccc(-c2cc(cc(c2)[N+]([O-])=O)C(O)=O)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114199 BindingDB Entry DOI: 10.7270/Q2CN77X7
					More data for this Ligand-Target Pair

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