Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50006615 (CHEMBL3235483) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 292 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys... | J Med Chem 56: 7574-89 (2013) Article DOI: 10.1021/jm401184f BindingDB Entry DOI: 10.7270/Q2Z3215R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50006612 (CHEMBL3235488) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 784 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys... | J Med Chem 56: 7574-89 (2013) Article DOI: 10.1021/jm401184f BindingDB Entry DOI: 10.7270/Q2Z3215R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50006614 (CHEMBL3235482) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys... | J Med Chem 56: 7574-89 (2013) Article DOI: 10.1021/jm401184f BindingDB Entry DOI: 10.7270/Q2Z3215R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50435344 (CHEMBL2391541) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UCL School of Pharmacy Curated by ChEMBL | Assay Description Displacement of [3H]Epibatidine from human recombinant alpha2beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti... | Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50441458 (CHEMBL2436555) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]-epibatidine from human alpha2beta2 nAChR transfected in HEK293 cells by scintillation counting analysis | Bioorg Med Chem Lett 23: 5945-8 (2013) Article DOI: 10.1016/j.bmcl.2013.08.072 BindingDB Entry DOI: 10.7270/Q2ZK5J31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UCL School of Pharmacy Curated by ChEMBL | Assay Description Displacement of [3H]Epibatidine from human recombinant alpha2beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti... | Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50006613 (CHEMBL3235480) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys... | J Med Chem 56: 7574-89 (2013) Article DOI: 10.1021/jm401184f BindingDB Entry DOI: 10.7270/Q2Z3215R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2 (Homo sapiens (Human)) | BDBM50006616 (CHEMBL3235484) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys... | J Med Chem 56: 7574-89 (2013) Article DOI: 10.1021/jm401184f BindingDB Entry DOI: 10.7270/Q2Z3215R | |||||||||||
More data for this Ligand-Target Pair |