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Compile Data Set for Download or QSAR

Found 136 hits of ic50 for UniProtKB: P41143   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50225844
PNG
(CHEMBL56347)
Show SMILES CCOc1ccc2C(=O)C3C(C)C(C)(CN3CC3CC3)c2c1 |TLB:11:10:20.7.6:15.14|
Show InChI InChI=1S/C19H25NO2/c1-4-22-14-7-8-15-16(9-14)19(3)11-20(10-13-5-6-13)17(12(19)2)18(15)21/h7-9,12-13,17H,4-6,10-11H2,1-3H3
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n/an/a 0.0700n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for antagonistic activity against opioid receptor in electrically stimulated longitudinal muscle of guinea pig ileum

J Med Chem 29: 1861-4 (1986)


BindingDB Entry DOI: 10.7270/Q2HX1FW0
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50002346
PNG
(CHEMBL384584 | [D-pro10]Dynorphin A(1-11))
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O
Show InChI InChI=1S/C63H103N21O13/c1-5-37(4)51(58(94)80-44(20-13-29-74-63(70)71)59(95)84-30-14-21-48(84)57(93)81-45(60(96)97)17-9-10-26-64)83-54(90)43(19-12-28-73-62(68)69)78-53(89)42(18-11-27-72-61(66)67)79-55(91)46(31-36(2)3)82-56(92)47(33-38-15-7-6-8-16-38)77-50(87)35-75-49(86)34-76-52(88)41(65)32-39-22-24-40(85)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,85H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H,75,86)(H,76,88)(H,77,87)(H,78,89)(H,79,91)(H,80,94)(H,81,93)(H,82,92)(H,83,90)(H,96,97)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t37-,41-,42-,43-,44-,45-,46-,47-,48+,51-/m0/s1
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n/an/a 0.220n/an/an/an/an/an/a



Oregon State University

Curated by ChEMBL


Assay Description
Tested for opioid receptor agonistic activity in guinea pig ileum

J Med Chem 35: 4638-9 (1993)


BindingDB Entry DOI: 10.7270/Q2416XPM
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50226283
PNG
(CHEMBL172293)
Show SMILES [#6]-[#16]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6](-[#6])-c1ccccc1
Show InChI InChI=1S/C37H48N8O6S/c1-23(27-12-8-5-9-13-27)41-32(47)22-40-34(49)30(20-25-10-6-4-7-11-25)44-33(48)24(2)42-35(50)29(18-19-52-3)43-36(51)31(45-37(38)39)21-26-14-16-28(46)17-15-26/h4-17,23-24,29-31,46H,18-22H2,1-3H3,(H,40,49)(H,41,47)(H,42,50)(H,43,51)(H,44,48)(H4,38,39,45)/t23?,24-,29+,30-,31-/m0/s1
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n/an/a 0.280n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against opioid activity in guinea pig ileum

J Med Chem 29: 889-94 (1986)


BindingDB Entry DOI: 10.7270/Q2959KSW
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50123599
PNG
(ETORPHINE)
Show SMILES [H][C@@]1(C[C@]23C=C[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4O)[C@](C)(O)CCC |r,wU:15.17,20.21,25.33,1.0,wD:9.10,3.3,6.7,c:4,THB:17:16:13.12.14:3,(12.5,-39.62,;11.02,-39.23,;12.37,-38.48,;12.38,-36.94,;11.6,-38.27,;10.46,-37.1,;9.7,-38.44,;8.61,-39.53,;7.12,-39.12,;9.72,-36.9,;8.94,-35.56,;9.73,-33.87,;11.06,-34.63,;12.4,-33.87,;13.73,-34.64,;13.72,-36.18,;14.48,-34.84,;15.81,-34.06,;12.94,-34.84,;12.54,-35.75,;11.06,-36.16,;12.39,-32.32,;11.06,-31.55,;9.73,-32.32,;8.39,-31.55,;11,-40.77,;10.98,-42.3,;9.46,-40.75,;12.54,-40.79,;13.29,-42.14,;14.83,-42.16,)|
Show InChI InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17-,18-,21-,22-,23-,24+,25-/m1/s1
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n/an/a 0.300n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated the ability to protect against the irreversible antagonism of morphines effects by beta-FNA in guinea pig ileal longitudinal muscle.

J Med Chem 26: 1341-3 (1983)


BindingDB Entry DOI: 10.7270/Q2VH5R2F
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50013388
PNG
(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Show SMILES CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc13)C2(C)C |TLB:6:5:20:19.13.12|
Show InChI InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3
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n/an/a 0.5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
In vitro binding affinity against Opioid receptors from bovine caudate nucleus determined in presence of [3H]- bremazocine (0.5 nM)

J Med Chem 33: 737-41 (1990)


BindingDB Entry DOI: 10.7270/Q2SN09J6
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM60212
PNG
((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
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n/an/a 0.550n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin)

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50226282
PNG
(CHEMBL170858)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NC(C)c1ccccc1
Show InChI InChI=1S/C36H46N6O6S/c1-23(27-12-8-5-9-13-27)39-32(44)22-38-35(47)31(21-25-10-6-4-7-11-25)42-33(45)24(2)40-36(48)30(18-19-49-3)41-34(46)29(37)20-26-14-16-28(43)17-15-26/h4-17,23-24,29-31,43H,18-22,37H2,1-3H3,(H,38,47)(H,39,44)(H,40,48)(H,41,46)(H,42,45)/t23?,24-,29-,30+,31-/m0/s1
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n/an/a 0.590n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against opioid activity in guinea pig ileum

J Med Chem 29: 889-94 (1986)


BindingDB Entry DOI: 10.7270/Q2959KSW
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM60212
PNG
((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
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n/an/a 0.590n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin) in presence of 100 mM NaCl

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50224554
PNG
(Ethylketazocine)
Show SMILES CCOc1ccc2C(=O)C3C(C)C(C)(CCN3CC3CC3)c2c1 |THB:11:10:7.21.6:16.14.15|
Show InChI InChI=1S/C20H27NO2/c1-4-23-15-7-8-16-17(11-15)20(3)9-10-21(12-14-5-6-14)18(13(20)2)19(16)22/h7-8,11,13-14,18H,4-6,9-10,12H2,1-3H3
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n/an/a 0.600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated the ability to protect against the irreversible antagonism of morphines effects by beta-FNA in guinea pig ileal longitudinal muscle.

J Med Chem 26: 1341-3 (1983)


BindingDB Entry DOI: 10.7270/Q2VH5R2F
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50497034
PNG
(CHEMBL3249714)
Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2N)ccc3O |r,THB:11:10:18:5.6.7|
Show InChI InChI=1S/C20H26N2O3.ClH/c21-13-5-6-20(24)15-9-12-3-4-14(23)17-16(12)19(20,18(13)25-17)7-8-22(15)10-11-1-2-11;/h3-4,11,13,15,18,23-24H,1-2,5-10,21H2;1H/t13-,15-,18+,19+,20-;/m1./s1
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n/an/a 0.700n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin) in presence of 100 mM NaCl

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50497032
PNG
(CHEMBL3249922)
Show SMILES Cl.CN(C)[C@]1(CC[C@@](O)(CCc2ccccc2)CC1)c1ccc(Br)cc1 |r,wU:7.6,wD:4.2,(7.72,-11.54,;4.33,-7.03,;5.82,-7.44,;6.21,-8.93,;6.92,-6.36,;7.69,-7.68,;9.23,-7.68,;10,-6.36,;11.08,-5.26,;11.08,-7.44,;10.68,-8.93,;11.77,-10.02,;11.37,-11.51,;12.46,-12.59,;13.95,-12.2,;14.34,-10.7,;13.25,-9.62,;9.23,-5.02,;7.69,-5.02,;5.82,-5.26,;6.23,-3.75,;5.13,-2.65,;3.62,-3.06,;2.53,-1.97,;3.22,-4.57,;4.32,-5.66,)|
Show InChI InChI=1S/C22H28BrNO.ClH/c1-24(2)22(19-8-10-20(23)11-9-19)16-14-21(25,15-17-22)13-12-18-6-4-3-5-7-18;/h3-11,25H,12-17H2,1-2H3;1H/t21-,22-;
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n/an/a 0.800n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]naloxone from opioid receptor (unknown origin) by liquid scintillation counting

J Med Chem 22: 1157-8 (1979)


Article DOI: 10.1021/jm00196a001
BindingDB Entry DOI: 10.7270/Q2P2723B
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50497034
PNG
(CHEMBL3249714)
Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2N)ccc3O |r,THB:11:10:18:5.6.7|
Show InChI InChI=1S/C20H26N2O3.ClH/c21-13-5-6-20(24)15-9-12-3-4-14(23)17-16(12)19(20,18(13)25-17)7-8-22(15)10-11-1-2-11;/h3-4,11,13,15,18,23-24H,1-2,5-10,21H2;1H/t13-,15-,18+,19+,20-;/m1./s1
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n/an/a 0.910n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin)

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50001714
PNG
(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1C(C)(C)O)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |THB:8:7:22.21:4.3|
Show InChI InChI=1S/C26H35NO4/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3/t18-,19-,22-,24-,25+,26-/m1/s1
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n/an/a 1.30n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50010703
PNG
(CHEMBL443068 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Cys-A...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C69H112N24O14S2/c1-38(2)30-48(90-63(104)50(33-40-14-6-5-7-15-40)84-55(96)35-82-54(95)34-83-57(98)43(71)32-41-21-23-42(94)24-22-41)61(102)86-45(17-10-26-79-67(73)74)58(99)85-46(18-11-27-80-68(75)76)60(101)92-52-37-109-108-36-51(56(72)97)91-62(103)49(31-39(3)4)89-59(100)44(16-8-9-25-70)87-65(106)53-20-13-29-93(53)66(107)47(88-64(52)105)19-12-28-81-69(77)78/h5-7,14-15,21-24,38-39,43-53,94H,8-13,16-20,25-37,70-71H2,1-4H3,(H2,72,97)(H,82,95)(H,83,98)(H,84,96)(H,85,99)(H,86,102)(H,87,106)(H,88,105)(H,89,100)(H,90,104)(H,91,103)(H,92,101)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-/m0/s1
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n/an/a 1.30n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)

J Med Chem 33: 1874-9 (1990)


BindingDB Entry DOI: 10.7270/Q2FB51XH
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50059841
PNG
((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r|
Show InChI InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1
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n/an/a 1.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro opioid inhibitory activity against in guinea pig ileum

J Med Chem 29: 889-94 (1986)


BindingDB Entry DOI: 10.7270/Q2959KSW
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50013388
PNG
(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Show SMILES CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc13)C2(C)C |TLB:6:5:20:19.13.12|
Show InChI InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3
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n/an/a 1.5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptors

J Med Chem 35: 2374-84 (1992)


BindingDB Entry DOI: 10.7270/Q2GH9JKS
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50013388
PNG
(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Show SMILES CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc13)C2(C)C |TLB:6:5:20:19.13.12|
Show InChI InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3
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n/an/a 1.5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50123599
PNG
(ETORPHINE)
Show SMILES [H][C@@]1(C[C@]23C=C[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4O)[C@](C)(O)CCC |r,wU:15.17,20.21,25.33,1.0,wD:9.10,3.3,6.7,c:4,THB:17:16:13.12.14:3,(12.5,-39.62,;11.02,-39.23,;12.37,-38.48,;12.38,-36.94,;11.6,-38.27,;10.46,-37.1,;9.7,-38.44,;8.61,-39.53,;7.12,-39.12,;9.72,-36.9,;8.94,-35.56,;9.73,-33.87,;11.06,-34.63,;12.4,-33.87,;13.73,-34.64,;13.72,-36.18,;14.48,-34.84,;15.81,-34.06,;12.94,-34.84,;12.54,-35.75,;11.06,-36.16,;12.39,-32.32,;11.06,-31.55,;9.73,-32.32,;8.39,-31.55,;11,-40.77,;10.98,-42.3,;9.46,-40.75,;12.54,-40.79,;13.29,-42.14,;14.83,-42.16,)|
Show InChI InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17-,18-,21-,22-,23-,24+,25-/m1/s1
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n/an/a 1.70n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50002184
PNG
(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O
Show InChI InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1
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n/an/a 1.70n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)

J Med Chem 33: 1874-9 (1990)


BindingDB Entry DOI: 10.7270/Q2FB51XH
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50010701
PNG
(CHEMBL410616 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C69H112N24O14S2/c1-38(2)30-48(90-63(104)50(33-40-14-6-5-7-15-40)84-55(96)35-82-54(95)34-83-57(98)43(71)32-41-21-23-42(94)24-22-41)61(102)86-45(17-10-26-79-67(73)74)58(99)85-46(18-11-27-80-68(75)76)60(101)92-52-37-109-108-36-51(56(72)97)91-62(103)49(31-39(3)4)89-59(100)44(16-8-9-25-70)87-65(106)53-20-13-29-93(53)66(107)47(88-64(52)105)19-12-28-81-69(77)78/h5-7,14-15,21-24,38-39,43-53,94H,8-13,16-20,25-37,70-71H2,1-4H3,(H2,72,97)(H,82,95)(H,83,98)(H,84,96)(H,85,99)(H,86,102)(H,87,106)(H,88,105)(H,89,100)(H,90,104)(H,91,103)(H,92,101)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44-,45-,46-,47-,48-,49-,50-,51+,52+,53-/m0/s1
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n/an/a 1.80n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)

J Med Chem 33: 1874-9 (1990)


BindingDB Entry DOI: 10.7270/Q2FB51XH
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50226284
PNG
(CHEMBL170091)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:40:41:43.44.48:46,48:43:50:47.49.46,48:47:50:43.42.44,THB:42:41:43.44.48:46,42:43:41.50.49:46|
Show InChI InChI=1S/C38H52N6O6S/c1-23(41-37(50)31(12-13-51-2)42-35(48)30(39)17-25-8-10-29(45)11-9-25)34(47)43-32(18-24-6-4-3-5-7-24)36(49)40-22-33(46)44-38-19-26-14-27(20-38)16-28(15-26)21-38/h3-11,23,26-28,30-32,45H,12-22,39H2,1-2H3,(H,40,49)(H,41,50)(H,42,48)(H,43,47)(H,44,46)/t23-,26?,27?,28?,30-,31+,32-,38?/m0/s1
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n/an/a 2.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against opioid activity in guinea pig ileum

J Med Chem 29: 889-94 (1986)


BindingDB Entry DOI: 10.7270/Q2959KSW
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50002347
PNG
(CHEMBL425806 | [N-cyclopropyl methylTyr1, D-pro10]...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCC1CC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O
Show InChI InChI=1S/C67H109N21O13/c1-5-40(4)55(62(98)84-47(20-13-31-77-67(73)74)63(99)88-32-14-21-52(88)61(97)85-48(64(100)101)17-9-10-28-68)87-58(94)46(19-12-30-76-66(71)72)82-57(93)45(18-11-29-75-65(69)70)83-59(95)50(33-39(2)3)86-60(96)51(35-41-15-7-6-8-16-41)81-54(91)38-79-53(90)37-80-56(92)49(78-36-43-22-23-43)34-42-24-26-44(89)27-25-42/h6-8,15-16,24-27,39-40,43,45-52,55,78,89H,5,9-14,17-23,28-38,68H2,1-4H3,(H,79,90)(H,80,92)(H,81,91)(H,82,93)(H,83,95)(H,84,98)(H,85,97)(H,86,96)(H,87,94)(H,100,101)(H4,69,70,75)(H4,71,72,76)(H4,73,74,77)/t40-,45-,46-,47-,48-,49-,50-,51-,52+,55-/m0/s1
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n/an/a 2.20n/an/an/an/an/an/a



Oregon State University

Curated by ChEMBL


Assay Description
Tested for opioid receptor agonistic activity in guinea pig ileum

J Med Chem 35: 4638-9 (1993)


BindingDB Entry DOI: 10.7270/Q2416XPM
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50455774
PNG
(CHEMBL2092986)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@H](C1)C(C)(C)O)ccc3OCC(=C)C(=O)OC |TLB:25:23:16.1:18.19,THB:10:9:17:4.5.6|
Show InChI InChI=1S/C31H41NO6/c1-18(26(33)35-4)17-37-21-9-8-20-14-23-29-10-11-31(36-5,22(15-29)28(2,3)34)27-30(29,24(20)25(21)38-27)12-13-32(23)16-19-6-7-19/h8-9,19,22-23,27,34H,1,6-7,10-17H2,2-5H3/t22-,23-,27-,29-,30+,31-/m1/s1
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n/an/a 2.20n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50010706
PNG
(CHEMBL384250 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C69H112N24O14S2/c1-38(2)30-48(90-63(104)50(33-40-14-6-5-7-15-40)84-55(96)35-82-54(95)34-83-57(98)43(71)32-41-21-23-42(94)24-22-41)61(102)86-45(17-10-26-79-67(73)74)58(99)85-46(18-11-27-80-68(75)76)60(101)92-52-37-109-108-36-51(56(72)97)91-62(103)49(31-39(3)4)89-59(100)44(16-8-9-25-70)87-65(106)53-20-13-29-93(53)66(107)47(88-64(52)105)19-12-28-81-69(77)78/h5-7,14-15,21-24,38-39,43-53,94H,8-13,16-20,25-37,70-71H2,1-4H3,(H2,72,97)(H,82,95)(H,83,98)(H,84,96)(H,85,99)(H,86,102)(H,87,106)(H,88,105)(H,89,100)(H,90,104)(H,91,103)(H,92,101)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44-,45-,46-,47-,48-,49-,50-,51-,52+,53-/m0/s1
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n/an/a 2.30n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)

J Med Chem 33: 1874-9 (1990)


BindingDB Entry DOI: 10.7270/Q2FB51XH
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50013385
PNG
(CHEMBL166355 | methyl 2-[4-cyclopropylmethyl-10,17...)
Show SMILES COC(=O)C(=C)COC1CCC2(O)C3Cc4ccc(O)c5OC1[C@]2(CCN3CC1CC1)c45 |THB:20:31:11:26.24.25,16:15:11:26.24.25|
Show InChI InChI=1S/C25H31NO6/c1-14(23(28)30-2)13-31-18-7-8-25(29)19-11-16-5-6-17(27)21-20(16)24(25,22(18)32-21)9-10-26(19)12-15-3-4-15/h5-6,15,18-19,22,27,29H,1,3-4,7-13H2,2H3/t18?,19?,22?,24-,25?/m0/s1
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n/an/a 2.40n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
In vitro binding affinity against Opioid receptors from bovine caudate nucleus determined in presence of [3H]- bremazocine (0.5 nM)

J Med Chem 33: 737-41 (1990)


BindingDB Entry DOI: 10.7270/Q2SN09J6
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50001713
PNG
(CHEMBL143815 | methyl 2-[19-(1-hydroxy-1-methylbut...)
Show SMILES CCC[C@@](C)(O)[C@H]1C[C@]23C=C[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4OCC(=C)C(=O)OC |wU:3.2,20.22,wD:25.29,14.15,8.8,6.5,11.12,3.4,c:9,(9.11,-3.65,;7.57,-3.65,;6.8,-2.32,;5.26,-2.32,;5.23,-.78,;5.65,-3.81,;3.72,-2.32,;2.95,-.99,;1.41,-.96,;1.41,-2.5,;2.92,-2.11,;2.92,-3.65,;3.69,-5,;5.23,-5,;1.38,-3.65,;-.18,-4.02,;-1.65,-3.62,;-.88,-2.29,;-1.65,-.96,;-.9,.37,;.64,.37,;1.03,1.86,;1.97,3.07,;-.3,1.09,;-.72,-1.52,;.64,-2.29,;-3.19,-.96,;-3.96,-2.29,;-3.19,-3.62,;-3.96,-4.95,;-5.5,-4.95,;-6.27,-6.31,;-5.5,-7.64,;-7.81,-6.31,;-8.58,-7.64,;-8.58,-4.95,;-7.81,-3.62,)|
Show InChI InChI=1S/C30H39NO6/c1-7-10-27(3,33)21-16-28-11-12-30(21,35-6)26-29(28)13-14-31(4)22(28)15-19-8-9-20(24(37-26)23(19)29)36-17-18(2)25(32)34-5/h8-9,11-12,21-22,26,33H,2,7,10,13-17H2,1,3-6H3/t21-,22-,26-,27-,28-,29+,30-/m1/s1
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n/an/a 2.40n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50010702
PNG
(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O |r,wU:38.46,19.26,4.4,2.2,88.90,128.132,144.148,70.71,105.107,wD:57.58,30.34,8.15,84.87,97.99,114.116,136.140,(27.24,-21.93,;25.83,-21.28,;25.7,-19.76,;26.97,-18.87,;24.28,-19.11,;24.14,-17.56,;25.39,-16.68,;26.8,-17.34,;25.25,-15.13,;23.87,-14.49,;23.73,-12.97,;22.32,-12.32,;22.18,-10.79,;20.78,-10.14,;19.51,-11.03,;20.63,-8.6,;26.5,-14.25,;26.41,-12.7,;25.05,-12.02,;27.68,-11.87,;29.07,-12.56,;30.37,-11.71,;31.74,-12.4,;33.01,-11.53,;34.37,-12.24,;34.46,-13.77,;35.67,-11.39,;27.59,-10.31,;28.87,-9.48,;30.26,-10.18,;28.78,-7.92,;27.42,-7.24,;26.12,-8.09,;24.76,-7.41,;26.21,-9.64,;30.05,-7.09,;29.97,-5.53,;28.6,-4.85,;31.24,-4.7,;32.63,-5.4,;32.72,-6.92,;31.45,-7.77,;31.55,-9.31,;32.93,-9.99,;34.21,-9.14,;34.11,-7.6,;31.15,-3.14,;32.43,-2.31,;33.81,-3.01,;32.34,-.76,;33.61,.08,;33.52,1.63,;32.16,2.32,;34.8,2.47,;34.71,4.01,;36,4.86,;37.37,4.17,;35.91,6.4,;37.19,7.24,;34.53,7.1,;33.23,6.24,;33.34,4.69,;32.06,3.84,;30.68,4.52,;29.39,3.71,;30.58,6.06,;31.86,6.91,;23.04,-19.99,;21.65,-19.34,;23.18,-21.52,;21.92,-22.42,;22.06,-23.97,;20.82,-24.84,;19.43,-24.2,;18.16,-25.1,;16.78,-24.46,;16.64,-22.94,;15.51,-25.35,;20.12,-21.58,;18.85,-22.48,;19.94,-19.61,;21.09,-18.4,;20.31,-16.91,;18.66,-17.19,;18.69,-18.75,;17.33,-19.47,;17.28,-21.01,;16.02,-18.66,;14.66,-19.38,;14.61,-20.92,;13.25,-21.64,;13.2,-23.18,;11.84,-23.91,;11.79,-25.45,;13.36,-18.57,;13.41,-17.03,;12,-19.29,;10.69,-18.48,;10.74,-16.94,;9.44,-16.12,;9.49,-14.58,;8.08,-16.85,;9.33,-19.2,;9.28,-20.74,;8.03,-18.39,;6.67,-19.11,;6.61,-20.65,;5.26,-21.37,;5.2,-22.91,;3.85,-23.64,;3.79,-25.18,;5.36,-18.3,;5.41,-16.76,;4,-19.02,;2.69,-18.21,;2.75,-16.67,;1.44,-15.85,;.01,-16.43,;-.98,-15.25,;-.16,-13.95,;-.59,-12.47,;.48,-11.36,;1.97,-11.73,;2.4,-13.21,;1.33,-14.32,;1.34,-18.93,;1.28,-20.47,;.03,-18.12,;-1.33,-18.84,;-1.38,-20.38,;-2.74,-21.1,;-4.05,-20.29,;-2.79,-22.64,;-2.64,-18.03,;-2.59,-16.49,;-4,-18.75,;-5.3,-17.94,;-5.25,-16.4,;-6.56,-15.58,;-7.92,-16.31,;-6.51,-14.04,;-6.66,-18.66,;-6.71,-20.2,;-7.97,-17.85,;-9.33,-18.57,;-9.38,-20.11,;-10.74,-20.83,;-10.79,-22.37,;-9.48,-23.19,;-12.15,-23.1,;-10.63,-17.76,;-11.99,-18.48,;-10.58,-16.22,)|
Show InChI InChI=1S/C99H155N31O23/c1-7-55(6)81(129-86(142)66(28-18-40-112-98(107)108)118-83(139)65(27-17-39-111-97(105)106)120-88(144)70(44-54(4)5)125-89(145)71(46-56-21-9-8-10-22-56)117-79(135)52-115-78(134)51-116-82(138)61(102)45-57-31-33-59(131)34-32-57)94(150)122-67(29-19-41-113-99(109)110)95(151)130-42-20-30-75(130)93(149)121-64(26-14-16-38-101)85(141)124-69(43-53(2)3)87(143)119-63(25-13-15-37-100)84(140)126-72(47-58-50-114-62-24-12-11-23-60(58)62)90(146)128-74(49-80(136)137)92(148)127-73(48-77(104)133)91(147)123-68(96(152)153)35-36-76(103)132/h8-12,21-24,31-34,50,53-55,61,63-75,81,114,131H,7,13-20,25-30,35-49,51-52,100-102H2,1-6H3,(H2,103,132)(H2,104,133)(H,115,134)(H,116,138)(H,117,135)(H,118,139)(H,119,143)(H,120,144)(H,121,149)(H,122,150)(H,123,147)(H,124,141)(H,125,145)(H,126,140)(H,127,148)(H,128,146)(H,129,142)(H,136,137)(H,152,153)(H4,105,106,111)(H4,107,108,112)(H4,109,110,113)/t55-,61-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,81-/m0/s1
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n/an/a 2.5n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)

J Med Chem 33: 1874-9 (1990)


BindingDB Entry DOI: 10.7270/Q2FB51XH
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50000296
PNG
(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1
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n/an/a 2.60n/an/an/an/an/an/a



Oregon State University

Curated by ChEMBL


Assay Description
Tested for opioid receptor agonistic activity in guinea pig ileum

J Med Chem 35: 4638-9 (1993)


BindingDB Entry DOI: 10.7270/Q2416XPM
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50226289
PNG
(CHEMBL369354)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)CC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:49:44:51:48.50.47,49:48:51:44.43.45,THB:47:46:43:48.50.49,47:48:43:46.51.45|
Show InChI InChI=1S/C39H54N6O6S/c1-24(41-37(50)32(13-14-52-3)42-36(49)31(40)18-26-9-11-30(46)12-10-26)35(48)43-33(19-25-7-5-4-6-8-25)38(51)45(2)23-34(47)44-39-20-27-15-28(21-39)17-29(16-27)22-39/h4-12,24,27-29,31-33,46H,13-23,40H2,1-3H3,(H,41,50)(H,42,49)(H,43,48)(H,44,47)/t24-,27?,28?,29?,31-,32+,33-,39?/m0/s1
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n/an/a 2.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro opioid inhibitory activity against in guinea pig ileum

J Med Chem 29: 889-94 (1986)


BindingDB Entry DOI: 10.7270/Q2959KSW
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50497036
PNG
(CHEMBL3249715)
Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@@H]2N)ccc3O |r,THB:11:10:18:5.6.7|
Show InChI InChI=1S/C20H26N2O3.ClH/c21-13-5-6-20(24)15-9-12-3-4-14(23)17-16(12)19(20,18(13)25-17)7-8-22(15)10-11-1-2-11;/h3-4,11,13,15,18,23-24H,1-2,5-10,21H2;1H/t13-,15+,18-,19-,20+;/m0./s1
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n/an/a 2.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin)

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50226286
PNG
(CHEMBL296148)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCc1ccccc1
Show InChI InChI=1S/C35H44N6O6S/c1-23(39-35(47)29(17-18-48-2)40-33(45)28(36)19-25-13-15-27(42)16-14-25)32(44)41-30(20-24-9-5-3-6-10-24)34(46)38-22-31(43)37-21-26-11-7-4-8-12-26/h3-16,23,28-30,42H,17-22,36H2,1-2H3,(H,37,43)(H,38,46)(H,39,47)(H,40,45)(H,41,44)/t23-,28-,29+,30-/m0/s1
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n/an/a 3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro opioid inhibitory activity against in guinea pig ileum

J Med Chem 29: 889-94 (1986)


BindingDB Entry DOI: 10.7270/Q2959KSW
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50225843
PNG
(CHEMBL293990)
Show SMILES [H][C@@]12Oc3c4c(CC5N(CC6CC6)CCC14[C@@]5(O)CC[C@@]2([H])NC(=O)CN(CCCl)CCCl)ccc3O |THB:3:4:16:8.14.13,17:16:4.5.6:8.14.13,9:8:16:4.5.6|
Show InChI InChI=1S/C26H35Cl2N3O4/c27-8-11-30(12-9-28)15-21(33)29-18-5-6-26(34)20-13-17-3-4-19(32)23-22(17)25(26,24(18)35-23)7-10-31(20)14-16-1-2-16/h3-4,16,18,20,24,32,34H,1-2,5-15H2,(H,29,33)/t18-,20?,24+,25?,26-/m1/s1
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n/an/a 3.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for agonist activity against opioid receptor in electrically stimulated longitudinal muscle of guinea pig ileum

J Med Chem 29: 1861-4 (1986)


BindingDB Entry DOI: 10.7270/Q2HX1FW0
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM54795
PNG
((4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7...)
Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1
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n/an/a 4.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin) in presence of 100 mM NaCl

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50013387
PNG
(4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azape...)
Show SMILES CC(=C)C(=O)OC1CCC2(O)C3Cc4ccc(O)c5OC1[C@]2(CCN3CC1CC1)c45 |THB:18:29:9:24.22.23,14:13:9:24.22.23|
Show InChI InChI=1S/C24H29NO5/c1-13(2)22(27)29-17-7-8-24(28)18-11-15-5-6-16(26)20-19(15)23(24,21(17)30-20)9-10-25(18)12-14-3-4-14/h5-6,14,17-18,21,26,28H,1,3-4,7-12H2,2H3/t17?,18?,21?,23-,24?/m0/s1
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n/an/a 5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
In vitro binding affinity against Opioid receptors from bovine caudate nucleus determined in presence of [3H]- bremazocine (0.5 nM)

J Med Chem 33: 737-41 (1990)


BindingDB Entry DOI: 10.7270/Q2SN09J6
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50497120
PNG
(CHEMBL3274598)
Show SMILES [H][C@@]12Cc3ccc(O)cc3[C@]3(CCCC[C@@]13[H])CCN2CCc1ccc(cc1)N1C(=O)C=CC1=O |r,c:36,THB:20:19:15:9.3.2|
Show InChI InChI=1S/C28H30N2O3/c31-22-9-6-20-17-25-23-3-1-2-13-28(23,24(20)18-22)14-16-29(25)15-12-19-4-7-21(8-5-19)30-26(32)10-11-27(30)33/h4-11,18,23,25,31H,1-3,12-17H2/t23-,25+,28+/m0/s1
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n/an/a 5.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]naloxone from opiate receptor (unknown origin) after 10 mins

J Med Chem 20: 1020-4 (1977)


Article DOI: 10.1021/jm00218a006
BindingDB Entry DOI: 10.7270/Q2GB271H
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM54795
PNG
((4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7...)
Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1
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n/an/a 5.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin)

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50000788
PNG
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r|
Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1
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n/an/a 5.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]naloxone from opiate receptor (unknown origin) after 10 mins

J Med Chem 20: 1020-4 (1977)


Article DOI: 10.1021/jm00218a006
BindingDB Entry DOI: 10.7270/Q2GB271H
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM60212
PNG
((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
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n/an/a 5.70n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptors

J Med Chem 35: 2374-84 (1992)


BindingDB Entry DOI: 10.7270/Q2GH9JKS
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM60212
PNG
((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
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n/an/a 5.70n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50000091
PNG
((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Show SMILES CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 |TLB:6:5:13.21.15:11,14:13:11:5.3.4,THB:20:21:11:5.3.4|
Show InChI InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1
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n/an/a 5.90n/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against opioid receptor in Guinea pig ileum

J Med Chem 35: 48-56 (1992)


BindingDB Entry DOI: 10.7270/Q2J105DC
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50013386
PNG
(4,5alpha-Epoxy-3,6alpha, 14-trihydroxy-6beta-(2-ca...)
Show SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45C(Oc1c24)C1(CC(=C)C(=O)O1)CCC35O |TLB:29:28:18.4.5:7.13.12,THB:8:7:28:18.4.5,27:28:18.4.5:7.13.12,17:18:28:7.13.12|
Show InChI InChI=1S/C24H27NO5/c1-13-11-22(30-20(13)27)6-7-24(28)17-10-15-4-5-16(26)19-18(15)23(24,21(22)29-19)8-9-25(17)12-14-2-3-14/h4-5,14,17,21,26,28H,1-3,6-12H2/t17?,21?,22?,23-,24?/m0/s1
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n/an/a 6n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
In vitro binding affinity against Opioid receptors from bovine caudate nucleus determined in presence of [3H]- bremazocine (0.5 nM)

J Med Chem 33: 737-41 (1990)


BindingDB Entry DOI: 10.7270/Q2SN09J6
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50010704
PNG
(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O
Show InChI InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1
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n/an/a 7.5n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)

J Med Chem 33: 1874-9 (1990)


BindingDB Entry DOI: 10.7270/Q2FB51XH
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50497036
PNG
(CHEMBL3249715)
Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@@H]2N)ccc3O |r,THB:11:10:18:5.6.7|
Show InChI InChI=1S/C20H26N2O3.ClH/c21-13-5-6-20(24)15-9-12-3-4-14(23)17-16(12)19(20,18(13)25-17)7-8-22(15)10-11-1-2-11;/h3-4,11,13,15,18,23-24H,1-2,5-10,21H2;1H/t13-,15+,18-,19-,20+;/m0./s1
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n/an/a 9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H] naloxone from opioid receptor (unknown origin) in presence of 100 mM NaCl

J Med Chem 20: 1100-2 (1977)


Article DOI: 10.1021/jm00218a023
BindingDB Entry DOI: 10.7270/Q2DJ5JMF
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50071860
PNG
(12-(2-Amino-3-phenyl-propionylamino)-9-benzyl-5,5-...)
Show SMILES CC1(C)SCCSC[C@@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(N)=O |r|
Show InChI InChI=1S/C28H37N5O4S2/c1-28(2)23(24(30)34)33-26(36)21(16-19-11-7-4-8-12-19)31-27(37)22(17-38-13-14-39-28)32-25(35)20(29)15-18-9-5-3-6-10-18/h3-12,20-23H,13-17,29H2,1-2H3,(H2,30,34)(H,31,37)(H,32,35)(H,33,36)/t20-,21-,22+,23+/m0/s1
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n/an/a 9.10n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Agonistic activity tested in vitro in guinea pig ileum opioid

Bioorg Med Chem Lett 8: 2681-4 (1999)


BindingDB Entry DOI: 10.7270/Q24T6JWP
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50000092
PNG
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1|
Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Opioid receptors with [3H]naloxone binding in the absence of NaCl

J Med Chem 23: 985-90 (1980)


BindingDB Entry DOI: 10.7270/Q2HD7XT0
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50001705
PNG
(CHEMBL343167 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Show SMILES COC(=O)C(=C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Show InChI InChI=1S/C25H29NO6/c1-14(23(28)30-2)13-31-18-6-5-16-11-19-25(29)8-7-17(27)22-24(25,20(16)21(18)32-22)9-10-26(19)12-15-3-4-15/h5-6,15,19,22,29H,1,3-4,7-13H2,2H3/t19-,22+,24+,25-/m1/s1
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n/an/a 10n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50000790
PNG
(CHEMBL76023 | methyl 2-[4-cyclopropylmethyl-10,17-...)
Show SMILES COC(=O)C(=C)CO[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45
Show InChI InChI=1S/C25H31NO6/c1-14(23(28)30-2)13-31-18-7-8-25(29)19-11-16-5-6-17(27)21-20(16)24(25,22(18)32-21)9-10-26(19)12-15-3-4-15/h5-6,15,18-19,22,27,29H,1,3-4,7-13H2,2H3/t18-,19-,22+,24+,25-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptors

J Med Chem 35: 2374-84 (1992)


BindingDB Entry DOI: 10.7270/Q2GH9JKS
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50000793
PNG
(4-cyclopropylmethyl-14-(2-oxiranylmethoxy)-12-oxa-...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OC[C@H]1CO1
Show InChI InChI=1S/C23H29NO5/c25-16-4-3-14-9-18-23(26)6-5-17(28-12-15-11-27-15)21-22(23,19(14)20(16)29-21)7-8-24(18)10-13-1-2-13/h3-4,13,15,17-18,21,25-26H,1-2,5-12H2/t15-,17-,18-,21+,22+,23-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptors

J Med Chem 35: 2374-84 (1992)


BindingDB Entry DOI: 10.7270/Q2GH9JKS
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM82551
PNG
(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O |r|
Show InChI InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50000790
PNG
(CHEMBL76023 | methyl 2-[4-cyclopropylmethyl-10,17-...)
Show SMILES COC(=O)C(=C)CO[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45
Show InChI InChI=1S/C25H31NO6/c1-14(23(28)30-2)13-31-18-7-8-25(29)19-11-16-5-6-17(27)21-20(16)24(25,22(18)32-21)9-10-26(19)12-15-3-4-15/h5-6,15,18-19,22,27,29H,1,3-4,7-13H2,2H3/t18-,19-,22+,24+,25-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membrane

J Med Chem 35: 4589-94 (1993)


BindingDB Entry DOI: 10.7270/Q27S7PCK
More data for this
Ligand-Target Pair
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