BindingDB PrimarySearch

Found 2 hits of ic50 for UniProtKB: P21447
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-dependent translocase ABCB1 bd-verapamil (Mus musculus (Mouse))	BDBM227643 (Vinblastine) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	22.5
University of Washington					Assay Description For the data shown, 25 nM BD-verapamil was added to various P-gp nanodisc concentrations in the presence of 1 μM empty nanodiscs, and 50 nM BD-v...				Biochemistry 56: 2506-2517 (2017) Article DOI: 10.1021/acs.biochem.6b01245 BindingDB Entry DOI: 10.7270/Q20G3J1N
University of Washington					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 bd-verapamil (Mus musculus (Mouse))	BDBM81939 (CAS_52-53-9 \| NSC_62969 \| VERAPAMIL) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.73E+5	n/a	n/a	n/a	n/a	n/a	22.5
University of Washington					Assay Description For the data shown, 25 nM BD-verapamil was added to various P-gp nanodisc concentrations in the presence of 1 μM empty nanodiscs, and 50 nM BD-v...				Biochemistry 56: 2506-2517 (2017) Article DOI: 10.1021/acs.biochem.6b01245 BindingDB Entry DOI: 10.7270/Q20G3J1N
University of Washington					More data for this Ligand-Target Pair