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Compile Data Set for Download or QSAR

Found 96 hits of ic50 for UniProtKB: P22607   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255620
PNG
(US9475815, 5)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC[C@](C)(N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H26N6OS/c1-13-6-14-8-18(30-20(14)17(7-13)29-3)16-9-15(10-27-5-4-22(2,24)11-27)28-19(16)21(23)25-12-26-28/h6-9,12H,4-5,10-11,24H2,1-3H3,(H2,23,25,26)/t22-/m0/s1
PDB

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US Patent
n/an/a 7.40n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255624
PNG
(US9475815, 9)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC[C@H](N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C21H24N6OS/c1-12-5-13-7-18(29-20(13)17(6-12)28-2)16-8-15(10-26-4-3-14(22)9-26)27-19(16)21(23)24-11-25-27/h5-8,11,14H,3-4,9-10,22H2,1-2H3,(H2,23,24,25)/t14-/m0/s1
PDB

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n/an/a 7.40n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255633
PNG
(US9475815, 18)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CNCC(N)=O)n2ncnc(N)c12
Show InChI InChI=1S/C19H20N6O2S/c1-10-3-11-5-15(28-18(11)14(4-10)27-2)13-6-12(7-22-8-16(20)26)25-17(13)19(21)23-9-24-25/h3-6,9,22H,7-8H2,1-2H3,(H2,20,26)(H2,21,23,24)
PDB

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n/an/a 7.80n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255636
PNG
(US9475815, 21)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C(C2)NCCO)n2ncnc(N)c12
Show InChI InChI=1S/C23H28N6O3S/c1-13-5-14-7-20(33-22(14)19(6-13)32-2)16-8-15(29-21(16)23(24)26-12-27-29)9-28-10-17(18(31)11-28)25-3-4-30/h5-8,12,17-18,25,30-31H,3-4,9-11H2,1-2H3,(H2,24,26,27)
PDB

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n/an/a 8n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255701
PNG
(US9475815, 86)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCCC(C2)N(C)C)n2ncnc(N)c12
Show InChI InChI=1S/C24H30N6OS/c1-15-8-16-10-21(32-23(16)20(9-15)31-4)19-11-18(30-22(19)24(25)26-14-27-30)13-29-7-5-6-17(12-29)28(2)3/h8-11,14,17H,5-7,12-13H2,1-4H3,(H2,25,26,27)
PDB

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n/an/a 9.60n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255712
PNG
(US9475815, 97)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)N2CC[C@](C)(N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H24N6O2S/c1-12-6-13-8-17(31-19(13)16(7-12)30-3)14-9-15(28-18(14)20(23)25-11-26-28)21(29)27-5-4-22(2,24)10-27/h6-9,11H,4-5,10,24H2,1-3H3,(H2,23,25,26)/t22-/m0/s1
PDB

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n/an/a 9.90n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255707
PNG
(US9475815, 92)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN[C@@H](CC(N)=O)C(O)=O)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C21H22N6O4S/c1-10-3-11-5-16(32-19(11)15(4-10)31-2)13-6-12(27-18(13)20(23)25-9-26-27)8-24-14(21(29)30)7-17(22)28/h3-6,9,14,24H,7-8H2,1-2H3,(H2,22,28)(H,29,30)(H2,23,25,26)/t14-/m0/s1
PDB

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n/an/a 11.7n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255711
PNG
(US9475815, 96)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCN(CC2)C(=O)CO)n2ncnc(N)c12
Show InChI InChI=1S/C23H26N6O3S/c1-14-7-15-9-19(33-22(15)18(8-14)32-2)17-10-16(29-21(17)23(24)25-13-26-29)11-27-3-5-28(6-4-27)20(31)12-30/h7-10,13,30H,3-6,11-12H2,1-2H3,(H2,24,25,26)
PDB

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n/an/a 11.9n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255713
PNG
(US9475815, 98)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)NC2CCNC2=O)n2ncnc(N)c12
Show InChI InChI=1S/C21H20N6O3S/c1-10-5-11-7-16(31-18(11)15(6-10)30-2)12-8-14(27-17(12)19(22)24-9-25-27)21(29)26-13-3-4-23-20(13)28/h5-9,13H,3-4H2,1-2H3,(H,23,28)(H,26,29)(H2,22,24,25)
PDB

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US Patent
n/an/a 13.1n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255719
PNG
(US9475815, 104)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)N2CCC[C@@H](N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H24N6O2S/c1-12-6-13-8-18(31-20(13)17(7-12)30-2)15-9-16(28-19(15)21(24)25-11-26-28)22(29)27-5-3-4-14(23)10-27/h6-9,11,14H,3-5,10,23H2,1-2H3,(H2,24,25,26)/t14-/m1/s1
PDB

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n/an/a 14.6n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255631
PNG
(US9475815, 16)
Show SMILES CCN[C@H]1CCN(Cc2cc(-c3cc4cc(C)cc(OC)c4s3)c3c(N)ncnn23)C1 |r|
Show InChI InChI=1S/C23H28N6OS/c1-4-25-16-5-6-28(11-16)12-17-10-18(21-23(24)26-13-27-29(17)21)20-9-15-7-14(2)8-19(30-3)22(15)31-20/h7-10,13,16,25H,4-6,11-12H2,1-3H3,(H2,24,26,27)/t16-/m0/s1
PDB

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n/an/a 15.5n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255669
PNG
(US9475815, 54)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCN[C@](C)(N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H27N7OS/c1-13-6-14-8-18(31-20(14)17(7-13)30-3)16-9-15(29-19(16)21(23)25-12-27-29)10-28-5-4-26-22(2,24)11-28/h6-9,12,26H,4-5,10-11,24H2,1-3H3,(H2,23,25,27)/t22-/m0/s1
PDB

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n/an/a 15.8n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255670
PNG
(US9475815, 55)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCC[C@@H](N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H26N6OS/c1-13-6-14-8-19(30-21(14)18(7-13)29-2)17-9-16(11-27-5-3-4-15(23)10-27)28-20(17)22(24)25-12-26-28/h6-9,12,15H,3-5,10-11,23H2,1-2H3,(H2,24,25,26)/t15-/m1/s1
PDB

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n/an/a 18.7n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255703
PNG
(US9475815, 88)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCC(O)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C22H25N5O2S/c1-13-7-14-9-19(30-21(14)18(8-13)29-2)17-10-15(11-26-5-3-16(28)4-6-26)27-20(17)22(23)24-12-25-27/h7-10,12,16,28H,3-6,11H2,1-2H3,(H2,23,24,25)
PDB

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US Patent
n/an/a 21.3n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255621
PNG
(US9475815, 6)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN[C@@H]2CCNC2=O)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-17(30-19(12)16(6-11)29-2)14-8-13(9-24-15-3-4-23-21(15)28)27-18(14)20(22)25-10-26-27/h5-8,10,15,24H,3-4,9H2,1-2H3,(H,23,28)(H2,22,25,26)/t15-/m1/s1
PDB

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n/an/a 21.7n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255700
PNG
(US9475815, 85)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN[C@@H](C)C(N)=O)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C20H22N6O2S/c1-10-4-12-6-16(29-18(12)15(5-10)28-3)14-7-13(8-23-11(2)20(22)27)26-17(14)19(21)24-9-25-26/h4-7,9,11,23H,8H2,1-3H3,(H2,22,27)(H2,21,24,25)/t11-/m0/s1
PDB

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n/an/a 22.1n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255671
PNG
(US9475815, 56)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCC[C@H](N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H26N6OS/c1-13-6-14-8-19(30-21(14)18(7-13)29-2)17-9-16(11-27-5-3-4-15(23)10-27)28-20(17)22(24)25-12-26-28/h6-9,12,15H,3-5,10-11,23H2,1-2H3,(H2,24,25,26)/t15-/m0/s1
PDB

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n/an/a 22.6n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255630
PNG
(US9475815, 15)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC[C@@H](C2)N(C)C)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-20(31-22(15)19(8-14)30-4)18-10-17(29-21(18)23(24)25-13-26-29)12-28-6-5-16(11-28)27(2)3/h7-10,13,16H,5-6,11-12H2,1-4H3,(H2,24,25,26)/t16-/m0/s1
PDB

UniProtKB/SwissProt

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n/an/a 23n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255706
PNG
(US9475815, 91)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C2)n2ncnc(N)c12
Show InChI InChI=1S/C20H21N5O2S/c1-11-3-12-5-17(28-19(12)16(4-11)27-2)15-6-13(7-24-8-14(26)9-24)25-18(15)20(21)22-10-23-25/h3-6,10,14,26H,7-9H2,1-2H3,(H2,21,22,23)
PDB

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n/an/a 23.9n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255635
PNG
(US9475815, 20)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCNC(=O)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C22H24N6O2S/c1-13-7-14-9-18(31-21(14)17(8-13)30-2)16-10-15(28-20(16)22(23)25-12-26-28)11-27-5-3-19(29)24-4-6-27/h7-10,12H,3-6,11H2,1-2H3,(H,24,29)(H2,23,25,26)
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n/an/a 24.8n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255720
PNG
(US9475815, 105)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)N2CCC[C@](C)(N)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C23H26N6O2S/c1-13-7-14-9-18(32-20(14)17(8-13)31-3)15-10-16(29-19(15)21(24)26-12-27-29)22(30)28-6-4-5-23(2,25)11-28/h7-10,12H,4-6,11,25H2,1-3H3,(H2,24,26,27)/t23-/m0/s1
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n/an/a 25.7n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255634
PNG
(US9475815, 19)
Show SMILES CCN(CC)C1CCN(Cc2cc(-c3cc4cc(C)cc(OC)c4s3)c3c(N)ncnn23)C1
Show InChI InChI=1S/C25H32N6OS/c1-5-30(6-2)18-7-8-29(13-18)14-19-12-20(23-25(26)27-15-28-31(19)23)22-11-17-9-16(3)10-21(32-4)24(17)33-22/h9-12,15,18H,5-8,13-14H2,1-4H3,(H2,26,27,28)
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n/an/a 27.2n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255704
PNG
(US9475815, 89)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCCN(C)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C23H28N6OS/c1-15-9-16-11-20(31-22(16)19(10-15)30-3)18-12-17(29-21(18)23(24)25-14-26-29)13-28-6-4-5-27(2)7-8-28/h9-12,14H,4-8,13H2,1-3H3,(H2,24,25,26)
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n/an/a 28.2n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255682
PNG
(US9475815, 67)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN(C)CCC(N)=O)n2ncnc(N)c12
Show InChI InChI=1S/C21H24N6O2S/c1-12-6-13-8-17(30-20(13)16(7-12)29-3)15-9-14(10-26(2)5-4-18(22)28)27-19(15)21(23)24-11-25-27/h6-9,11H,4-5,10H2,1-3H3,(H2,22,28)(H2,23,24,25)
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n/an/a 28.4n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255716
PNG
(US9475815, 101)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)N2CCC(O)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C22H23N5O3S/c1-12-7-13-9-18(31-20(13)17(8-12)30-2)15-10-16(27-19(15)21(23)24-11-25-27)22(29)26-5-3-14(28)4-6-26/h7-11,14,28H,3-6H2,1-2H3,(H2,23,24,25)
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n/an/a 29.1n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255702
PNG
(US9475815, 87)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN[C@H]2CC[C@H](CC2)N(C)C)n2ncnc(N)c12 |r,wU:20.25,17.18,(3.78,3.41,;2.7,2.32,;1.21,2.72,;.89,4.23,;-.58,4.7,;-.97,6.19,;-1.72,3.67,;-1.4,2.17,;-2.31,.92,;-1.4,-.33,;.06,.15,;.06,1.69,;-1.8,-1.81,;-.89,-3.06,;-1.8,-4.3,;-1.4,-5.79,;.09,-6.19,;1.18,-5.1,;.78,-3.61,;1.87,-2.53,;3.35,-2.93,;3.75,-4.41,;2.66,-5.5,;4.44,-1.84,;5.93,-2.24,;4.05,-.35,;-3.26,-3.83,;-4.6,-4.6,;-5.93,-3.83,;-5.93,-2.29,;-4.6,-1.52,;-4.6,.02,;-3.26,-2.29,)|
Show InChI InChI=1S/C25H32N6OS/c1-15-9-16-11-22(33-24(16)21(10-15)32-4)20-12-19(31-23(20)25(26)28-14-29-31)13-27-17-5-7-18(8-6-17)30(2)3/h9-12,14,17-18,27H,5-8,13H2,1-4H3,(H2,26,28,29)/t17-,18+
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n/an/a 29.1n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255683
PNG
(US9475815, 68)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCN(CC2)C(N)=O)n2ncnc(N)c12
Show InChI InChI=1S/C22H25N7O2S/c1-13-7-14-9-18(32-20(14)17(8-13)31-2)16-10-15(29-19(16)21(23)25-12-26-29)11-27-3-5-28(6-4-27)22(24)30/h7-10,12H,3-6,11H2,1-2H3,(H2,24,30)(H2,23,25,26)
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n/an/a 29.3n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255734
PNG
(US9475815, 119)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(COCC(C)N)n2ncnc(N)c12
Show InChI InChI=1S/C20H23N5O2S/c1-11-4-13-6-17(28-19(13)16(5-11)26-3)15-7-14(9-27-8-12(2)21)25-18(15)20(22)23-10-24-25/h4-7,10,12H,8-9,21H2,1-3H3,(H2,22,23,24)
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n/an/a 29.7n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255705
PNG
(US9475815, 90)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC[C@H](C2)N(C)C)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-20(31-22(15)19(8-14)30-4)18-10-17(29-21(18)23(24)25-13-26-29)12-28-6-5-16(11-28)27(2)3/h7-10,13,16H,5-6,11-12H2,1-4H3,(H2,24,25,26)/t16-/m1/s1
PDB

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n/an/a 30.3n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255729
PNG
(US9475815, 114)
Show SMILES CCNC(=O)COCc1cc(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn12
Show InChI InChI=1S/C21H23N5O3S/c1-4-23-18(27)10-29-9-14-8-15(19-21(22)24-11-25-26(14)19)17-7-13-5-12(2)6-16(28-3)20(13)30-17/h5-8,11H,4,9-10H2,1-3H3,(H,23,27)(H2,22,24,25)
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n/an/a 30.5n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255629
PNG
(US9475815, 14)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN[C@H]2CCNC2=O)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-17(30-19(12)16(6-11)29-2)14-8-13(9-24-15-3-4-23-21(15)28)27-18(14)20(22)25-10-26-27/h5-8,10,15,24H,3-4,9H2,1-2H3,(H,23,28)(H2,22,25,26)/t15-/m0/s1
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n/an/a 33.4n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255678
PNG
(US9475815, 63)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CNC(=O)C2)n2ncnc(N)c12
Show InChI InChI=1S/C20H20N6O2S/c1-11-3-12-5-16(29-19(12)15(4-11)28-2)14-6-13(7-25-8-17(27)23-10-25)26-18(14)20(21)22-9-24-26/h3-6,9H,7-8,10H2,1-2H3,(H,23,27)(H2,21,22,24)
PDB

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n/an/a 34.5n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255732
PNG
(US9475815, 117)
Show SMILES CNCCOCc1cc(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn12
Show InChI InChI=1S/C20H23N5O2S/c1-12-6-13-8-17(28-19(13)16(7-12)26-3)15-9-14(10-27-5-4-22-2)25-18(15)20(21)23-11-24-25/h6-9,11,22H,4-5,10H2,1-3H3,(H2,21,23,24)
PDB

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n/an/a 34.8n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255715
PNG
(US9475815, 100)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)N2CCC(C2)N(C)C)n2ncnc(N)c12
Show InChI InChI=1S/C23H26N6O2S/c1-13-7-14-9-19(32-21(14)18(8-13)31-4)16-10-17(29-20(16)22(24)25-12-26-29)23(30)28-6-5-15(11-28)27(2)3/h7-10,12,15H,5-6,11H2,1-4H3,(H2,24,25,26)
PDB

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n/an/a 35.9n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255632
PNG
(US9475815, 17)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCNC(C2)C(=O)N(C)C)n2ncnc(N)c12
Show InChI InChI=1S/C24H29N7O2S/c1-14-7-15-9-20(34-22(15)19(8-14)33-4)17-10-16(31-21(17)23(25)27-13-28-31)11-30-6-5-26-18(12-30)24(32)29(2)3/h7-10,13,18,26H,5-6,11-12H2,1-4H3,(H2,25,27,28)
PDB

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n/an/a 36.9n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255724
PNG
(US9475815, 109)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(COC[C@@H]2CCCN2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H25N5O2S/c1-13-6-14-8-19(30-21(14)18(7-13)28-2)17-9-16(11-29-10-15-4-3-5-24-15)27-20(17)22(23)25-12-26-27/h6-9,12,15,24H,3-5,10-11H2,1-2H3,(H2,23,25,26)/t15-/m0/s1
PDB

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n/an/a 37.1n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255699
PNG
(US9475815, 84)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC[C@@H](O)C2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C21H23N5O2S/c1-12-5-13-7-18(29-20(13)17(6-12)28-2)16-8-14(9-25-4-3-15(27)10-25)26-19(16)21(22)23-11-24-26/h5-8,11,15,27H,3-4,9-10H2,1-2H3,(H2,22,23,24)/t15-/m1/s1
PDB

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n/an/a 39.1n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255637
PNG
(US9475815, 22)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCC(C2)NCC(C)O)n2ncnc(N)c12
Show InChI InChI=1S/C24H30N6O2S/c1-14-6-16-8-21(33-23(16)20(7-14)32-3)19-9-18(30-22(19)24(25)27-13-28-30)12-29-5-4-17(11-29)26-10-15(2)31/h6-9,13,15,17,26,31H,4-5,10-12H2,1-3H3,(H2,25,27,28)
PDB

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n/an/a 41.8n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255676
PNG
(US9475815, 61)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CNCC2CCN(C)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H30N6OS/c1-15-8-17-10-21(32-23(17)20(9-15)31-3)19-11-18(30-22(19)24(25)27-14-28-30)13-26-12-16-4-6-29(2)7-5-16/h8-11,14,16,26H,4-7,12-13H2,1-3H3,(H2,25,27,28)
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n/an/a 43.5n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255733
PNG
(US9475815, 118)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CO[C@@H]2CCNC2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C21H23N5O2S/c1-12-5-13-7-18(29-20(13)17(6-12)27-2)16-8-14(10-28-15-3-4-23-9-15)26-19(16)21(22)24-11-25-26/h5-8,11,15,23H,3-4,9-10H2,1-2H3,(H2,22,24,25)/t15-/m1/s1
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n/an/a 45n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255722
PNG
(US9475815, 107)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(COCCN2CCCC2)n2ncnc(N)c12
Show InChI InChI=1S/C23H27N5O2S/c1-15-9-16-11-20(31-22(16)19(10-15)29-2)18-12-17(28-21(18)23(24)25-14-26-28)13-30-8-7-27-5-3-4-6-27/h9-12,14H,3-8,13H2,1-2H3,(H2,24,25,26)
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n/an/a 46.1n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255673
PNG
(US9475815, 58)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CNCCN2CCC(O)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H30N6O2S/c1-15-9-16-11-21(33-23(16)20(10-15)32-2)19-12-17(30-22(19)24(25)27-14-28-30)13-26-5-8-29-6-3-18(31)4-7-29/h9-12,14,18,26,31H,3-8,13H2,1-2H3,(H2,25,27,28)
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n/an/a 46.7n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255687
PNG
(US9475815, 72)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CNCCO)n2ncnc(N)c12
Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-16(27-18(12)15(6-11)26-2)14-8-13(9-21-3-4-25)24-17(14)19(20)22-10-23-24/h5-8,10,21,25H,3-4,9H2,1-2H3,(H2,20,22,23)
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n/an/a 47.2n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255674
PNG
(US9475815, 59)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCCN(CCO)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H30N6O2S/c1-16-10-17-12-21(33-23(17)20(11-16)32-2)19-13-18(30-22(19)24(25)26-15-27-30)14-29-5-3-4-28(6-7-29)8-9-31/h10-13,15,31H,3-9,14H2,1-2H3,(H2,25,26,27)
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n/an/a 47.7n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255694
PNG
(US9475815, 79)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCCC2c2ccc(C)cc2)n2ncnc(N)c12
Show InChI InChI=1S/C28H29N5OS/c1-17-6-8-19(9-7-17)23-5-4-10-32(23)15-21-14-22(26-28(29)30-16-31-33(21)26)25-13-20-11-18(2)12-24(34-3)27(20)35-25/h6-9,11-14,16,23H,4-5,10,15H2,1-3H3,(H2,29,30,31)
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n/an/a 48.6n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255680
PNG
(US9475815, 65)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CNCCC2CCCN2C)n2ncnc(N)c12
Show InChI InChI=1S/C24H30N6OS/c1-15-9-16-11-21(32-23(16)20(10-15)31-3)19-12-18(30-22(19)24(25)27-14-28-30)13-26-7-6-17-5-4-8-29(17)2/h9-12,14,17,26H,4-8,13H2,1-3H3,(H2,25,27,28)
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n/an/a 49.5n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255672
PNG
(US9475815, 57)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CNC(C)(C)CN2CCCC2)n2ncnc(N)c12
Show InChI InChI=1S/C25H32N6OS/c1-16-9-17-11-21(33-23(17)20(10-16)32-4)19-12-18(31-22(19)24(26)27-15-29-31)13-28-25(2,3)14-30-7-5-6-8-30/h9-12,15,28H,5-8,13-14H2,1-4H3,(H2,26,27,29)
PDB

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n/an/a 53.3n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255735
PNG
(US9475815, 120)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(COCCN)n2ncnc(N)c12
Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-16(27-18(12)15(6-11)25-2)14-8-13(9-26-4-3-20)24-17(14)19(21)22-10-23-24/h5-8,10H,3-4,9,20H2,1-2H3,(H2,21,22,23)
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n/an/a 53.9n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255679
PNG
(US9475815, 64)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCN(CC(N)=O)CC2)n2ncnc(N)c12
Show InChI InChI=1S/C23H27N7O2S/c1-14-7-15-9-19(33-22(15)18(8-14)32-2)17-10-16(30-21(17)23(25)26-13-27-30)11-28-3-5-29(6-4-28)12-20(24)31/h7-10,13H,3-6,11-12H2,1-2H3,(H2,24,31)(H2,25,26,27)
PDB

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n/an/a 56.4n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P


(Homo sapiens (Human))
BDBM255725
PNG
(US9475815, 110)
Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(COC[C@H]2CCCN2)n2ncnc(N)c12 |r|
Show InChI InChI=1S/C22H25N5O2S/c1-13-6-14-8-19(30-21(14)18(7-13)28-2)17-9-16(11-29-10-15-4-3-5-24-15)27-20(17)22(23)25-12-26-27/h6-9,12,15,24H,3-5,10-11H2,1-2H3,(H2,23,25,26)/t15-/m1/s1
PDB

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n/an/a 57.4n/an/an/an/a7.022



BAYER INTELLETUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...


US Patent US9475815 (2016)


BindingDB Entry DOI: 10.7270/Q2862FC7
More data for this
Ligand-Target Pair
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