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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human)) | BDBM86283 (CAS_345-78-8 | CAS_39069-52-8 | GS 39783 | N,N'...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
IntelliSyn Pharma Curated by ChEMBL | Assay Description Positive allosteric modulation at human GABA-B 1b expressed in CHO cells co-expressing rat GABA-B2 assessed as potentiation of GABA-induced inhibitio... | Bioorg Med Chem Lett 27: 2239-2258 (2017) Article DOI: 10.1016/j.bmcl.2017.03.084 BindingDB Entry DOI: 10.7270/Q2VT1VJJ | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human)) | BDBM86283 (CAS_345-78-8 | CAS_39069-52-8 | GS 39783 | N,N'...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 741 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S binding | Bioorg Med Chem Lett 17: 6206-11 (2007) Article DOI: 10.1016/j.bmcl.2007.09.023 BindingDB Entry DOI: 10.7270/Q2N300RD | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
