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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 189361   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIF11 [15-368]


(Homo sapiens (Human))
BDBM189361
PNG
(SRI35564)
Show SMILES Cc1ccc(cc1)C1C(C#N)=C(N)Nc2ncnn12 |t:11|
Show InChI InChI=1S/C13H12N6/c1-8-2-4-9(5-3-8)11-10(6-14)12(15)18-13-16-7-17-19(11)13/h2-5,7,11H,15H2,1H3,(H,16,17,18)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.18E+5n/an/an/an/a7.025



Southern Research Institute



Assay Description
Compounds were first tested in triplicates at 100 uM; hit compounds were further tested with a 10-point twofold serial dilution to confirm their acti...


Chem Biol Drug Des 88: 178-87 (2016)


Article DOI: 10.1111/cbdd.12744
BindingDB Entry DOI: 10.7270/Q2NK3CV8
More data for this
Ligand-Target Pair