Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells by [14C]AMG uptake assay | Bioorg Med Chem 20: 4117-27 (2012) Article DOI: 10.1016/j.bmc.2012.04.053 BindingDB Entry DOI: 10.7270/Q26111CJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 16.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 mins | J Med Chem 55: 7828-40 (2012) Article DOI: 10.1021/jm300884k BindingDB Entry DOI: 10.7270/Q2MW2J9K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake | J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of SGLT2 (unknown origin) | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127387 BindingDB Entry DOI: 10.7270/Q2DZ0D1D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard Curated by ChEMBL | Assay Description Inhibition of human SGLT2 | Eur J Med Chem 184: (2019) Article DOI: 10.1016/j.ejmech.2019.111773 BindingDB Entry DOI: 10.7270/Q2TT4V97 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of SGLT2 | Bioorg Med Chem Lett 21: 2472-5 (2011) Article DOI: 10.1016/j.bmcl.2011.02.056 BindingDB Entry DOI: 10.7270/Q25Q4WD2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake | Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a... | Bioorg Med Chem Lett 24: 1528-31 (2014) Article DOI: 10.1016/j.bmcl.2014.01.077 BindingDB Entry DOI: 10.7270/Q2PG1T6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a... | Bioorg Med Chem Lett 24: 1528-31 (2014) Article DOI: 10.1016/j.bmcl.2014.01.077 BindingDB Entry DOI: 10.7270/Q2PG1T6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de Lisboa Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose ... | J Med Chem 60: 568-579 (2017) Article DOI: 10.1021/acs.jmedchem.6b01134 BindingDB Entry DOI: 10.7270/Q2KK9F2F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Rattus norvegicus) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of rat SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake | Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Suisan Kaisha, Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake | Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in Xenopus oocytes assessed as reduction in [14C]AMG uptake after 1 hr by liquid scintillation counting method | J Med Chem 63: 3834-3867 (2020) Article DOI: 10.1021/acs.jmedchem.9b01237 BindingDB Entry DOI: 10.7270/Q26113PD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 185 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 mins | J Med Chem 55: 7828-40 (2012) Article DOI: 10.1021/jm300884k BindingDB Entry DOI: 10.7270/Q2MW2J9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in CHO-K1 cells by [14C]AMG uptake assay | Bioorg Med Chem 20: 4117-27 (2012) Article DOI: 10.1016/j.bmc.2012.04.053 BindingDB Entry DOI: 10.7270/Q26111CJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Suisan Kaisha, Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake | Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of SGLT1 (unknown origin) | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127387 BindingDB Entry DOI: 10.7270/Q2DZ0D1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard Curated by ChEMBL | Assay Description Inhibition of human SGLT1 | Eur J Med Chem 184: (2019) Article DOI: 10.1016/j.ejmech.2019.111773 BindingDB Entry DOI: 10.7270/Q2TT4V97 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptake | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptake | J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of SGLT1 | Bioorg Med Chem Lett 21: 2472-5 (2011) Article DOI: 10.1016/j.bmcl.2011.02.056 BindingDB Entry DOI: 10.7270/Q25Q4WD2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Rattus norvegicus) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of rat SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake | Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 499 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de Lisboa Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose ... | J Med Chem 60: 568-579 (2017) Article DOI: 10.1021/acs.jmedchem.6b01134 BindingDB Entry DOI: 10.7270/Q2KK9F2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 536 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake | Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 752 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake by fluorescence polarization assay | Bioorg Med Chem Lett 18: 4944-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.036 BindingDB Entry DOI: 10.7270/Q27944J7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungnam National University Curated by ChEMBL | Assay Description Inhibition of sEH (unknown origin) assessed as substrate PHOME hydrolysis after 1 hr by fluorescence method | Bioorg Med Chem Lett 24: 1895-900 (2014) Article DOI: 10.1016/j.bmcl.2014.03.014 BindingDB Entry DOI: 10.7270/Q22Z1722 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic triacylglycerol lipase (Sus scrofa (Pig)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 6.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Food Science and Biotechnology, Daegu University, Gyeongsan 38453, Republic of Korea. Curated by ChEMBL | Assay Description Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition measured afte... | Bioorg Med Chem Lett 27: 4889-4892 (2017) Article DOI: 10.1016/j.bmcl.2017.09.035 BindingDB Entry DOI: 10.7270/Q23J3GFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Sciences Center Curated by ChEMBL | Assay Description Inhibition of human CNT2 | Bioorg Med Chem Lett 19: 917-21 (2009) Article DOI: 10.1016/j.bmcl.2008.11.112 BindingDB Entry DOI: 10.7270/Q2K07440 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoshi University Curated by ChEMBL | Assay Description Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT2 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation... | Bioorg Med Chem 18: 2152-8 (2010) Article DOI: 10.1016/j.bmc.2010.01.077 BindingDB Entry DOI: 10.7270/Q2HD7VSQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Xiamen University Curated by ChEMBL | Assay Description Inhibition of diphenolase activity of mushroom tyrosinase | Bioorg Med Chem 15: 1568-71 (2007) Article DOI: 10.1016/j.bmc.2005.11.048 BindingDB Entry DOI: 10.7270/Q208650Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoshi University Curated by ChEMBL | Assay Description Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT1 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation... | Bioorg Med Chem 18: 2152-8 (2010) Article DOI: 10.1016/j.bmc.2010.01.077 BindingDB Entry DOI: 10.7270/Q2HD7VSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Sciences Center Curated by ChEMBL | Assay Description Inhibition of human CNT1 | Bioorg Med Chem Lett 19: 917-21 (2009) Article DOI: 10.1016/j.bmcl.2008.11.112 BindingDB Entry DOI: 10.7270/Q2K07440 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic triacylglycerol lipase (Sus scrofa (Pig)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Food Science and Biotechnology, Daegu University, Gyeongsan 38453, Republic of Korea. Curated by ChEMBL | Assay Description Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition measured afte... | Bioorg Med Chem Lett 27: 4889-4892 (2017) Article DOI: 10.1016/j.bmcl.2017.09.035 BindingDB Entry DOI: 10.7270/Q23J3GFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill... | ACS Med Chem Lett 6: 244-8 (2015) Article DOI: 10.1021/ml500343r BindingDB Entry DOI: 10.7270/Q2BK1F27 | |||||||||||
More data for this Ligand-Target Pair |