Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50051910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Lactobacillus casei)	BDBM50051910 ((R)-4-Amino-5-(4-{[(2,4-diamino-pyrido[2,3-d]pyrim...) Show SMILES CN(Cc1ccc(cc1)C(=O)NC(=O)[C@H](N)CCC(O)=O)c1cnc2nc(N)nc(N)c2c1 Show InChI InChI=1S/C21H24N8O4/c1-29(13-8-14-17(23)26-21(24)27-18(14)25-9-13)10-11-2-4-12(5-3-11)19(32)28-20(33)15(22)6-7-16(30)31/h2-5,8-9,15H,6-7,10,22H2,1H3,(H,30,31)(H,28,32,33)(H4,23,24,25,26,27)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)				J Med Chem 39: 1438-46 (1996) Article DOI: 10.1021/jm950786p BindingDB Entry DOI: 10.7270/Q2PK0F8N
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50051910 ((R)-4-Amino-5-(4-{[(2,4-diamino-pyrido[2,3-d]pyrim...) Show SMILES CN(Cc1ccc(cc1)C(=O)NC(=O)[C@H](N)CCC(O)=O)c1cnc2nc(N)nc(N)c2c1 Show InChI InChI=1S/C21H24N8O4/c1-29(13-8-14-17(23)26-21(24)27-18(14)25-9-13)10-11-2-4-12(5-3-11)19(32)28-20(33)15(22)6-7-16(30)31/h2-5,8-9,15H,6-7,10,22H2,1H3,(H,30,31)(H,28,32,33)(H4,23,24,25,26,27)/t15-/m1/s1	MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)				J Med Chem 39: 1438-46 (1996) Article DOI: 10.1021/jm950786p BindingDB Entry DOI: 10.7270/Q2PK0F8N
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Lactobacillus casei)	BDBM50051910 ((R)-4-Amino-5-(4-{[(2,4-diamino-pyrido[2,3-d]pyrim...) Show SMILES CN(Cc1ccc(cc1)C(=O)NC(=O)[C@H](N)CCC(O)=O)c1cnc2nc(N)nc(N)c2c1 Show InChI InChI=1S/C21H24N8O4/c1-29(13-8-14-17(23)26-21(24)27-18(14)25-9-13)10-11-2-4-12(5-3-11)19(32)28-20(33)15(22)6-7-16(30)31/h2-5,8-9,15H,6-7,10,22H2,1H3,(H,30,31)(H,28,32,33)(H4,23,24,25,26,27)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)				J Med Chem 39: 1438-46 (1996) Article DOI: 10.1021/jm950786p BindingDB Entry DOI: 10.7270/Q2PK0F8N
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Homo sapiens (Human))	BDBM50051910 ((R)-4-Amino-5-(4-{[(2,4-diamino-pyrido[2,3-d]pyrim...) Show SMILES CN(Cc1ccc(cc1)C(=O)NC(=O)[C@H](N)CCC(O)=O)c1cnc2nc(N)nc(N)c2c1 Show InChI InChI=1S/C21H24N8O4/c1-29(13-8-14-17(23)26-21(24)27-18(14)25-9-13)10-11-2-4-12(5-3-11)19(32)28-20(33)15(22)6-7-16(30)31/h2-5,8-9,15H,6-7,10,22H2,1H3,(H,30,31)(H,28,32,33)(H4,23,24,25,26,27)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human dihydrofolate reductase(in 50 microM dihydrofolic acid)				J Med Chem 39: 1438-46 (1996) Article DOI: 10.1021/jm950786p BindingDB Entry DOI: 10.7270/Q2PK0F8N
					More data for this Ligand-Target Pair