BindingDB PrimarySearch

Found 17 hits of ic50 for monomerid = 50176259
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of Norepinephrine				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of 5HT				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of SERT mediated 5-hydroxytryptamine uptake				Bioorg Med Chem Lett 18: 1674-80 (2008) Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of 5HT				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of Norepinephrine				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of 5HT				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of Norepinephrine				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of Norepinephrine				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of NET mediated norepinephrine uptake				Bioorg Med Chem Lett 18: 1674-80 (2008) Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of reuptake of 5HT				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of mu opioid receptor				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor				Bioorg Med Chem Lett 18: 1674-80 (2008) Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of mu opioid receptor				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of mu opioid receptor				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sepracor Inc. Curated by ChEMBL					Assay Description Inhibition of mu opioid receptor				Bioorg Med Chem Lett 16: 691-4 (2005) Article DOI: 10.1016/j.bmcl.2005.10.024 BindingDB Entry DOI: 10.7270/Q2MG7Q9D
Sepracor Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy				J Med Chem 51: 5932-42 (2008) Article DOI: 10.1021/jm8003152 BindingDB Entry DOI: 10.7270/Q23779MD
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50176259 ((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...) Show SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
University Medicine Greifswald Curated by ChEMBL					Assay Description Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysis				J Med Chem 62: 9890-9905 (2019) Article DOI: 10.1021/acs.jmedchem.9b01301 BindingDB Entry DOI: 10.7270/Q2QV3QSW
University Medicine Greifswald Curated by ChEMBL					More data for this Ligand-Target Pair