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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50191913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3


(Homo sapiens (Human))
BDBM50191913
PNG
(CHEMBL384350 | N-(2-methyl-4-(2-(pyrrolidin-1-yl)e...)
Show SMILES Cc1cc(CCN2CCCC2)ccc1Nc1nccc(n1)-c1c[nH]c2ncccc12
Show InChI InChI=1S/C24H26N6/c1-17-15-18(9-14-30-12-2-3-13-30)6-7-21(17)28-24-26-11-8-22(29-24)20-16-27-23-19(20)5-4-10-25-23/h4-8,10-11,15-16H,2-3,9,12-14H2,1H3,(H,25,27)(H,26,28,29)
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Similars

Article
PubMed
n/an/a 0.600n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Inhibition of CDK1/cyclinB by Flashplate assay


Bioorg Med Chem Lett 16: 4818-21 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.073
BindingDB Entry DOI: 10.7270/Q2571BNM
More data for this
Ligand-Target Pair