BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50197125   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))
BDBM50197125
PNG
(CHEMBL386021 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Show SMILES Clc1cccc2oc(cc(=O)c12)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1
Show InChI InChI=1S/C23H21ClN2O5/c24-16-2-1-3-19-22(16)17(27)11-21(31-19)23(28)25-15-6-8-26(9-7-15)12-14-4-5-18-20(10-14)30-13-29-18/h1-5,10-11,15H,6-9,12-13H2,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]MCH from MCHr1 expressed in IMR32 cells


J Med Chem 49: 6569-84 (2006)


Article DOI: 10.1021/jm060683e
BindingDB Entry DOI: 10.7270/Q2NG4Q7P
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))
BDBM50197125
PNG
(CHEMBL386021 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Show SMILES Clc1cccc2oc(cc(=O)c12)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1
Show InChI InChI=1S/C23H21ClN2O5/c24-16-2-1-3-19-22(16)17(27)11-21(31-19)23(28)25-15-6-8-26(9-7-15)12-14-4-5-18-20(10-14)30-13-29-18/h1-5,10-11,15H,6-9,12-13H2,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assay


J Med Chem 49: 6569-84 (2006)


Article DOI: 10.1021/jm060683e
BindingDB Entry DOI: 10.7270/Q2NG4Q7P
More data for this
Ligand-Target Pair