Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50216691 (3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using fluorescent peptide substrate by fluorescent assay | Science 317: 516-9 (2007) Article DOI: 10.1126/science.1143780 BindingDB Entry DOI: 10.7270/Q2D50MPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human)) | BDBM50216691 (3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT1 using fluorescent peptide substrate by fluorescent assay | Science 317: 516-9 (2007) Article DOI: 10.1126/science.1143780 BindingDB Entry DOI: 10.7270/Q2D50MPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Homo sapiens (Human)) | BDBM50216691 (3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT3 using fluorescent peptide substrate by fluorescent assay | Science 317: 516-9 (2007) Article DOI: 10.1126/science.1143780 BindingDB Entry DOI: 10.7270/Q2D50MPG | |||||||||||
More data for this Ligand-Target Pair |