Found 4 hits of ic50 for monomerid = 50321907 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50321907
((Z)-1-(4-Chlorophenyl)-3-[2-oxo-3-(1H-pyrrol-2-ylm...)Show SMILES Clc1ccc(NC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C20H15ClN4O2/c21-12-3-5-13(6-4-12)23-20(27)24-15-7-8-16-17(10-14-2-1-9-22-14)19(26)25-18(16)11-15/h1-11,22H,(H,25,26)(H2,23,24,27)/b17-10- | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of FLT3 |
Bioorg Med Chem 18: 4674-86 (2011)
Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50321907
((Z)-1-(4-Chlorophenyl)-3-[2-oxo-3-(1H-pyrrol-2-ylm...)Show SMILES Clc1ccc(NC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C20H15ClN4O2/c21-12-3-5-13(6-4-12)23-20(27)24-15-7-8-16-17(10-14-2-1-9-22-14)19(26)25-18(16)11-15/h1-11,22H,(H,25,26)(H2,23,24,27)/b17-10- | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of VEGFR3 |
Bioorg Med Chem 18: 4674-86 (2011)
Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50321907
((Z)-1-(4-Chlorophenyl)-3-[2-oxo-3-(1H-pyrrol-2-ylm...)Show SMILES Clc1ccc(NC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C20H15ClN4O2/c21-12-3-5-13(6-4-12)23-20(27)24-15-7-8-16-17(10-14-2-1-9-22-14)19(26)25-18(16)11-15/h1-11,22H,(H,25,26)(H2,23,24,27)/b17-10- | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of cKIT |
Bioorg Med Chem 18: 4674-86 (2011)
Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50321907
((Z)-1-(4-Chlorophenyl)-3-[2-oxo-3-(1H-pyrrol-2-ylm...)Show SMILES Clc1ccc(NC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C20H15ClN4O2/c21-12-3-5-13(6-4-12)23-20(27)24-15-7-8-16-17(10-14-2-1-9-22-14)19(26)25-18(16)11-15/h1-11,22H,(H,25,26)(H2,23,24,27)/b17-10- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of KDR |
Bioorg Med Chem 18: 4674-86 (2011)
Article DOI: 10.1016/j.bmc.2010.05.021 BindingDB Entry DOI: 10.7270/Q2QF8TVS |
More data for this Ligand-Target Pair | |