BindingDB PrimarySearch

Found 11 hits of ic50 for monomerid = 50424996
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 5 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of human HDAC5 by fluorescence assay				J Med Chem 56: 427-36 (2013) Article DOI: 10.1021/jm301254q BindingDB Entry DOI: 10.7270/Q2D79CRK
Heinrich Heine Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of human HDAC4 by fluorescence assay				J Med Chem 56: 427-36 (2013) Article DOI: 10.1021/jm301254q BindingDB Entry DOI: 10.7270/Q2D79CRK
Heinrich Heine Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
Sun Yat-sen University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of human HDAC6 by fluorescence assay				J Med Chem 56: 427-36 (2013) Article DOI: 10.1021/jm301254q BindingDB Entry DOI: 10.7270/Q2D79CRK
Heinrich Heine Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...				J Med Chem 63: 6959-6978 (2020) Article DOI: 10.1021/acs.jmedchem.0c00079 BindingDB Entry DOI: 10.7270/Q2125X6C
Sun Yat-sen University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of HDAC in human A2780 cells				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115108 BindingDB Entry DOI: 10.7270/Q2NV9NSQ
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of human HDAC1 by fluorescence assay				J Med Chem 56: 427-36 (2013) Article DOI: 10.1021/jm301254q BindingDB Entry DOI: 10.7270/Q2D79CRK
Heinrich Heine Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of HDAC in human Cal27 cells				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115108 BindingDB Entry DOI: 10.7270/Q2NV9NSQ
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	852	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of human HDAC11 by fluorescence assay				J Med Chem 56: 427-36 (2013) Article DOI: 10.1021/jm301254q BindingDB Entry DOI: 10.7270/Q2D79CRK
Heinrich Heine Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	881	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of human HDAC2 by fluorescence assay				J Med Chem 56: 427-36 (2013) Article DOI: 10.1021/jm301254q BindingDB Entry DOI: 10.7270/Q2D79CRK
Heinrich Heine Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50424996 (CHEMBL2312168) Show SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of human HDAC8 by fluorescence assay				J Med Chem 56: 427-36 (2013) Article DOI: 10.1021/jm301254q BindingDB Entry DOI: 10.7270/Q2D79CRK
Heinrich Heine Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair