Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [588-1147,K652R,M771V] (Human immunodeficiency virus type 1 group M subtyp...) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chimerix, Inc. US Patent | Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle... | US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y] (Human immunodeficiency virus type 1 group M subtyp...) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 5.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chimerix, Inc. US Patent | Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle... | US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1147,M628L,T656S,M771V,L797W,T802Y] (Human immunodeficiency virus type 1 group M subtyp...) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | >6.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chimerix, Inc. US Patent | Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle... | US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1147,V662I,F664L,F703Y,Q738M,M771V] (Human immunodeficiency virus type 1 group M subtyp...) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | >6.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chimerix, Inc. US Patent | Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle... | US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1147,M628L,N654N,K657R,T802F,K807E] (Human immunodeficiency virus type 1 group M subtyp...) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 6.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chimerix, Inc. US Patent | Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle... | US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y] (Human immunodeficiency virus type 1 group M subtyp...) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | >8.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chimerix, Inc. US Patent | Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle... | US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile salt export pump (Homo sapiens (Human)) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ... | Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 3 (Homo sapiens (Human)) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ... | Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human)) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... | Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 4 (Homo sapiens (Human)) | BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... | Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair |