Found 3 hits of kd for monomerid = 50157400 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Chromobox protein homolog 6
(Homo sapiens (Human)) | BDBM50157400
(CHEMBL3781600)Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc(Br)cc3)C(C)C)C(N)=O)[C@@]1([H])NC(=O)N2 |r| Show InChI InChI=1S/C63H89BrN12O14S/c1-37(2)53(74-60(87)47(33-38-15-7-6-8-16-38)70-56(83)40-23-25-41(64)26-24-40)62(89)71-46(34-39-21-27-42(78)28-22-39)59(86)68-44(18-12-14-32-76(3,4)5)57(84)72-48(35-77)61(88)69-45(29-30-52(80)81)58(85)67-43(55(65)82)17-11-13-31-66-51(79)20-10-9-19-50-54-49(36-91-50)73-63(90)75-54/h6-8,15-16,21-28,37,43-50,53-54,77H,9-14,17-20,29-36H2,1-5H3,(H13-,65,66,67,68,69,70,71,72,73,74,75,78,79,80,81,82,83,84,85,86,87,88,89,90)/p+1/t43-,44-,45-,46-,47-,48-,49-,50-,53-,54-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a |
University of Victoria
Curated by ChEMBL
| Assay Description Binding affinity to N-terminal His6-tagged human CBX6 (8 to 65 residues) expressed in Escherichia coli BL21 by surface plasmon resonance assay |
ACS Med Chem Lett 7: 139-44 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00378 BindingDB Entry DOI: 10.7270/Q2222WNZ |
More data for this Ligand-Target Pair | |
Chromobox protein homolog 7
(Homo sapiens (Human)) | BDBM50157400
(CHEMBL3781600)Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc(Br)cc3)C(C)C)C(N)=O)[C@@]1([H])NC(=O)N2 |r| Show InChI InChI=1S/C63H89BrN12O14S/c1-37(2)53(74-60(87)47(33-38-15-7-6-8-16-38)70-56(83)40-23-25-41(64)26-24-40)62(89)71-46(34-39-21-27-42(78)28-22-39)59(86)68-44(18-12-14-32-76(3,4)5)57(84)72-48(35-77)61(88)69-45(29-30-52(80)81)58(85)67-43(55(65)82)17-11-13-31-66-51(79)20-10-9-19-50-54-49(36-91-50)73-63(90)75-54/h6-8,15-16,21-28,37,43-50,53-54,77H,9-14,17-20,29-36H2,1-5H3,(H13-,65,66,67,68,69,70,71,72,73,74,75,78,79,80,81,82,83,84,85,86,87,88,89,90)/p+1/t43-,44-,45-,46-,47-,48-,49-,50-,53-,54-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a |
University of Victoria
Curated by ChEMBL
| Assay Description Binding affinity to human CBX7 V13A mutant expressed in Escherichia coli BL21 by surface plasmon resonance assay |
ACS Med Chem Lett 7: 139-44 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00378 BindingDB Entry DOI: 10.7270/Q2222WNZ |
More data for this Ligand-Target Pair | |
Chromobox protein homolog 7
(Homo sapiens (Human)) | BDBM50157400
(CHEMBL3781600)Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc(Br)cc3)C(C)C)C(N)=O)[C@@]1([H])NC(=O)N2 |r| Show InChI InChI=1S/C63H89BrN12O14S/c1-37(2)53(74-60(87)47(33-38-15-7-6-8-16-38)70-56(83)40-23-25-41(64)26-24-40)62(89)71-46(34-39-21-27-42(78)28-22-39)59(86)68-44(18-12-14-32-76(3,4)5)57(84)72-48(35-77)61(88)69-45(29-30-52(80)81)58(85)67-43(55(65)82)17-11-13-31-66-51(79)20-10-9-19-50-54-49(36-91-50)73-63(90)75-54/h6-8,15-16,21-28,37,43-50,53-54,77H,9-14,17-20,29-36H2,1-5H3,(H13-,65,66,67,68,69,70,71,72,73,74,75,78,79,80,81,82,83,84,85,86,87,88,89,90)/p+1/t43-,44-,45-,46-,47-,48-,49-,50-,53-,54-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a |
University of Victoria
Curated by ChEMBL
| Assay Description Binding affinity to N-terminal His6-tagged human CBX7 (8 to 62 residues) expressed in Escherichia coli BL21 by surface plasmon resonance assay |
ACS Med Chem Lett 7: 139-44 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00378 BindingDB Entry DOI: 10.7270/Q2222WNZ |
More data for this Ligand-Target Pair | |