Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine protease 1 (Bos taurus (bovine)) | BDBM33264 (guanidine, 4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.00E+3 | -30.6 | n/a | n/a | n/a | n/a | n/a | 7.6 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1424-1463]/[1502-1685] (West Nile virus (WNV)) | BDBM33264 (guanidine, 4) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.60E+4 | -27.2 | n/a | n/a | n/a | n/a | n/a | 8.5 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E] (Dengue virus 2 (strain TSV01)) | BDBM33264 (guanidine, 4) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.30E+4 | -26.3 | n/a | n/a | n/a | n/a | n/a | 8.5 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
More data for this Ligand-Target Pair |