Found 6 hits of ki for monomerid = 50035622 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Solute carrier organic anion transporter family member 2A1
(Homo sapiens (Human)) | BDBM50035622
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
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| DrugBank Article PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells |
Am J Physiol 277: 734-41 (1999)
Article DOI: 10.1152/ajpregu.1999.277.3.R734 BindingDB Entry DOI: 10.7270/Q2902524 |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 2A1
(Rattus norvegicus (Rat)) | BDBM50035622
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
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| Article PubMed
| 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells |
Am J Physiol 277: 734-41 (1999)
Article DOI: 10.1152/ajpregu.1999.277.3.R734 BindingDB Entry DOI: 10.7270/Q2902524 |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 2A1
(Mus musculus) | BDBM50035622
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| 104 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells |
Am J Physiol 277: 734-41 (1999)
Article DOI: 10.1152/ajpregu.1999.277.3.R734 BindingDB Entry DOI: 10.7270/Q2902524 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50035622
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
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| PDB PubMed
| 119 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Laboratories, Inc.
Curated by ChEMBL
| Assay Description Inhibitory Binding constant (n=2) to Prostanoid FP receptor expressed in bovine corpus luteum |
J Med Chem 43: 3400-7 (2000)
BindingDB Entry DOI: 10.7270/Q20864JG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin F2-alpha receptor
(BOVINE) | BDBM50035622
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
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| Article PubMed
| 129 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Research, Ltd
Curated by ChEMBL
| Assay Description Binding affinity for Prostanoid FP receptor of bovine corpus luteum |
Bioorg Med Chem Lett 14: 4525-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(BOVINE) | BDBM50035622
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Research Ltd.
Curated by ChEMBL
| Assay Description Displacement of [3H]PGF2 alpha from FP receptor in bovine corpus luteum membrane |
Bioorg Med Chem 17: 576-84 (2009)
Article DOI: 10.1016/j.bmc.2008.11.070 BindingDB Entry DOI: 10.7270/Q2RJ4JC1 |
More data for this Ligand-Target Pair | |