BindingDB PrimarySearch

Found 18 hits of ki for monomerid = 50160434
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cannabinoid receptor 1/2 (Rattus norvegicus (Rat)-Rattus norvegicus (rat))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biological Research Centre of the Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysis				Eur J Med Chem 178: 571-588 (2019) Article DOI: 10.1016/j.ejmech.2019.05.037 BindingDB Entry DOI: 10.7270/Q2Z60SD8
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Otago Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor				Eur J Med Chem 145: 770-789 (2018) Article DOI: 10.1016/j.ejmech.2017.11.076 BindingDB Entry DOI: 10.7270/Q2X069QD
University of Otago Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB2R expressed in HEK293 cell membranes measured after 90 mins				Eur J Med Chem 161: 239-251 (2019) Article DOI: 10.1016/j.ejmech.2018.09.070 BindingDB Entry DOI: 10.7270/Q29C71P7
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pontificia Universidad Cat£lica de Chile Curated by ChEMBL					Assay Description Inverse agonist activity at CB2 receptor (unknown origin)				Eur J Med Chem 124: 17-35 (2016) Article DOI: 10.1016/j.ejmech.2016.08.005 BindingDB Entry DOI: 10.7270/Q2Q2426V
Pontificia Universidad Cat£lica de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Binding affinity to cannabinoid CB2 receptor				J Med Chem 53: 4332-53 (2010) Article DOI: 10.1021/jm9018756 BindingDB Entry DOI: 10.7270/Q21R6QPF
Amgen, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity for human cannabinoid receptor 2 was determined by using [3H]-CP-55,940 as radioligand				Bioorg Med Chem Lett 15: 783-6 (2005) Article DOI: 10.1016/j.bmcl.2004.11.007 BindingDB Entry DOI: 10.7270/Q2MW2GN7
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]CP 55940 from human CB2 receptor in cell free system				Eur J Med Chem 46: 547-55 (2011) Article DOI: 10.1016/j.ejmech.2010.11.034 BindingDB Entry DOI: 10.7270/Q2CF9QCJ
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	35.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern					Assay Description Binding assay with hCB1 and hCB2 receptors.				Chem Biol 18: 1053-64 (2011) Article DOI: 10.1016/j.chembiol.2011.05.012 BindingDB Entry DOI: 10.7270/Q27W69PQ
University of Bern					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6505-10 (2007) Article DOI: 10.1016/j.bmcl.2007.09.089 BindingDB Entry DOI: 10.7270/Q2S75H5H
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 expressed in CHO cells after 90 mins by TopCount scintillation counting method				Eur J Med Chem 146: 68-78 (2018) Article DOI: 10.1016/j.ejmech.2018.01.034 BindingDB Entry DOI: 10.7270/Q2N58PXN
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6505-10 (2007) Article DOI: 10.1016/j.bmcl.2007.09.089 BindingDB Entry DOI: 10.7270/Q2S75H5H
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB1 expressed in CHO cells after 90 mins by TopCount scintillation counting method				Eur J Med Chem 146: 68-78 (2018) Article DOI: 10.1016/j.ejmech.2018.01.034 BindingDB Entry DOI: 10.7270/Q2N58PXN
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern					Assay Description Binding assay with hCB1 and hCB2 receptors.				Chem Biol 18: 1053-64 (2011) Article DOI: 10.1016/j.chembiol.2011.05.012 BindingDB Entry DOI: 10.7270/Q27W69PQ
University of Bern					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]CP 55940 from human CB1 receptor in cell free system				Eur J Med Chem 46: 547-55 (2011) Article DOI: 10.1016/j.ejmech.2010.11.034 BindingDB Entry DOI: 10.7270/Q2CF9QCJ
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Otago Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor				Eur J Med Chem 145: 770-789 (2018) Article DOI: 10.1016/j.ejmech.2017.11.076 BindingDB Entry DOI: 10.7270/Q2X069QD
University of Otago Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Binding affinity to cannabinoid CB1 receptor				J Med Chem 53: 4332-53 (2010) Article DOI: 10.1021/jm9018756 BindingDB Entry DOI: 10.7270/Q21R6QPF
Amgen, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes measured after 90 mins				Eur J Med Chem 161: 239-251 (2019) Article DOI: 10.1016/j.ejmech.2018.09.070 BindingDB Entry DOI: 10.7270/Q29C71P7
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50160434 ((6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pontificia Universidad Cat£lica de Chile Curated by ChEMBL					Assay Description Agonist activity at CB1 receptor (unknown origin)				Eur J Med Chem 124: 17-35 (2016) Article DOI: 10.1016/j.ejmech.2016.08.005 BindingDB Entry DOI: 10.7270/Q2Q2426V
Pontificia Universidad Cat£lica de Chile Curated by ChEMBL					More data for this Ligand-Target Pair