Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human)) | BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | 2.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of His6x-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-11) and [14C]-SAM by scintillation... | J Med Chem 53: 6028-39 (2010) Article DOI: 10.1021/jm100416n BindingDB Entry DOI: 10.7270/Q2251JDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human)) | BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Binding affinity to His6x-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using fluorescein-labeled H4(1-11) peptide by spectrofluorometer anal... | J Med Chem 53: 6028-39 (2010) Article DOI: 10.1021/jm100416n BindingDB Entry DOI: 10.7270/Q2251JDB | |||||||||||
More data for this Ligand-Target Pair |