Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM250432'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM250432 (US9464044, 22) Show SMILES CN(CC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1ccccc1F |r,wU:9.9,TLB:8:9:13:16.17.15,18:16:13:9.10.11,19:16:9:13.12.11,THB:18:10:13:16.17.15,17:16:9:13.12.11,17:12:9:16.18.15,(-3.29,2.5,;-3.29,.96,;-1.95,.19,;-.62,.96,;.15,2.3,;-1.39,2.3,;.72,.19,;.72,-1.35,;2.05,.96,;3.38,.19,;4.72,.96,;3.96,-.2,;3.94,-2.6,;2.55,-3.25,;3.38,-1.35,;4.72,-2.12,;6.04,-1.35,;5.15,-3.27,;6.04,.19,;7.53,-1.75,;8.62,-.66,;7.93,-3.23,;-4.62,.19,;-5.39,-1.14,;-3.85,-1.14,;-5.95,.96,;-5.95,2.5,;-7.29,3.27,;-8.62,2.5,;-8.62,.96,;-7.29,.19,;-7.29,-1.35,)| Show InChI InChI=1S/C23H30FN3O4S/c1-27(32(30,31)18-5-3-2-4-17(18)24)13-22(6-7-22)21(29)26-19-15-8-14-9-16(19)12-23(10-14,11-15)20(25)28/h2-5,14-16,19H,6-13H2,1H3,(H2,25,28)(H,26,29)/t14?,15?,16?,19-,23?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	6.0	25
AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION US Patent					Assay Description The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...				US Patent US9464044 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JH0
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