BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1' and Ligand = 'BDBM50401910'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50401910 (CHEMBL2207217) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [gamma33P]ATP from human TBK1 expressed in insect sf21 cells measured for 30 mins				J Med Chem 56: 2726-37 (2013) Article DOI: 10.1021/jm4000227 BindingDB Entry DOI: 10.7270/Q24Q7WCF
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50401910 (CHEMBL2207217) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human IKKepsilon expressed in insect sf21 cells using MBP as substrate measured for 30 mins				J Med Chem 56: 2726-37 (2013) Article DOI: 10.1021/jm4000227 BindingDB Entry DOI: 10.7270/Q24Q7WCF
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50401910 (CHEMBL2207217) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human Aurora B expressed in insect sf21 cells using LRRLSLGLRRLSLGLRRLSLGLRRLSLG peptide as substrate measured for 30 mins				J Med Chem 56: 2726-37 (2013) Article DOI: 10.1021/jm4000227 BindingDB Entry DOI: 10.7270/Q24Q7WCF
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50401910 (CHEMBL2207217) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [gamma33P]ATP from human PDK1 expressed in insect sf21 cells measured for 30 mins				J Med Chem 56: 2726-37 (2013) Article DOI: 10.1021/jm4000227 BindingDB Entry DOI: 10.7270/Q24Q7WCF
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50401910 (CHEMBL2207217) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
MRC Technology Curated by ChEMBL					Assay Description Inhibition of PDK1 by radiometry				Bioorg Med Chem Lett 22: 7169-73 (2012) Article DOI: 10.1016/j.bmcl.2012.09.063 BindingDB Entry DOI: 10.7270/Q2TT4S45
MRC Technology Curated by ChEMBL					More data for this Ligand-Target Pair