Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50024748'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50024748 (CHEMBL3343187) Show SMILES Cc1ccc(c(C)c1)-n1c(C)nc2ccc(cc2c1=O)C(=O)c1cnn(C)c1O |(30.83,-34.46,;29.51,-35.26,;29.55,-36.8,;28.23,-37.6,;26.89,-36.85,;26.84,-35.32,;25.49,-34.58,;28.16,-34.52,;25.57,-37.65,;25.61,-39.2,;26.96,-39.95,;24.28,-40.01,;22.92,-39.26,;21.61,-40.06,;20.26,-39.31,;20.23,-37.77,;21.54,-36.98,;22.89,-37.71,;24.21,-36.9,;24.17,-35.36,;18.88,-37.03,;18.85,-35.49,;17.57,-37.82,;17.43,-39.36,;15.94,-39.71,;15.14,-38.39,;13.61,-38.27,;16.14,-37.23,;15.79,-35.73,)| Show InChI InChI=1S/C22H20N4O3/c1-12-5-8-19(13(2)9-12)26-14(3)24-18-7-6-15(10-16(18)22(26)29)20(27)17-11-23-25(4)21(17)28/h5-11,28H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...				Bioorg Med Chem 22: 5194-211 (2014) Article DOI: 10.1016/j.bmc.2014.08.011 BindingDB Entry DOI: 10.7270/Q2DF6SRG
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