BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A' and Ligand = 'BDBM10755'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	292	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	361	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ...				J Med Chem 33: 3020-3 (1990) BindingDB Entry DOI: 10.7270/Q2VM4FGR
Pfizer Central Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (GUINEA PIG)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	495	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 267: 961-70 (1993) BindingDB Entry DOI: 10.7270/Q2125R5V
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (GUINEA PIG)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 267: 961-70 (1993) BindingDB Entry DOI: 10.7270/Q2125R5V
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (GUINEA PIG)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 267: 961-70 (1993) BindingDB Entry DOI: 10.7270/Q2125R5V
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	457	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human 5HT3A receptor expressed in HEK293 cells by FMP assay				J Med Chem 50: 4616-29 (2007) Article DOI: 10.1021/jm070574f BindingDB Entry DOI: 10.7270/Q2J67HRC
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (RAT)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Response at rat 5-hydroxytryptamine 3a receptor expressed in xenopus oocytes				Bioorg Med Chem Lett 14: 1849-53 (2004) Article DOI: 10.1016/j.bmcl.2003.09.104 BindingDB Entry DOI: 10.7270/Q2PK0GQW
University of Florida Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	178	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced response				Bioorg Med Chem Lett 21: 58-61 (2010) Article DOI: 10.1016/j.bmcl.2010.11.080 BindingDB Entry DOI: 10.7270/Q2474B4Q
AMRI Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a
Virtua Drug Ltd Curated by ChEMBL					Assay Description Agonist activity at wild type mouse 5HT3A receptor expressed in Xenopus oocyte by two-electrode voltage patch clamp method				Bioorg Med Chem 17: 5796-805 (2009) Article DOI: 10.1016/j.bmc.2009.07.022 BindingDB Entry DOI: 10.7270/Q2HH6M1M
Virtua Drug Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	141	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 10 uM 5-chloroindole-induced increase in intracell...				Bioorg Med Chem Lett 21: 58-61 (2010) Article DOI: 10.1016/j.bmcl.2010.11.080 BindingDB Entry DOI: 10.7270/Q2474B4Q
AMRI Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)