Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50056402'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (RAT)	BDBM50056402 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3-aza-b...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CC2CCC(CC2)C1 |TLB:14:15:21.22:18.19,(7.65,-14.52,;7.65,-12.98,;6.3,-12.21,;4.96,-12.98,;3.63,-12.21,;2.29,-12.98,;3.63,-10.66,;2.3,-9.89,;4.96,-9.87,;6.3,-10.65,;7.63,-9.87,;7.63,-8.33,;8.98,-10.64,;10.31,-9.87,;11.65,-10.62,;12.98,-9.85,;15.15,-9.38,;15.16,-10.46,;13.44,-11.25,;12.67,-12.46,;14.32,-11.58,;15.91,-12.53,;16.7,-11.39,;14.32,-10.2,)| Show InChI InChI=1S/C18H25ClN2O3/c1-23-17-9-16(20)15(19)8-14(17)18(22)24-7-6-21-10-12-2-3-13(11-21)5-4-12/h8-9,12-13H,2-7,10-11,20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligand				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50056402 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3-aza-b...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CC2CCC(CC2)C1 |TLB:14:15:21.22:18.19,(7.65,-14.52,;7.65,-12.98,;6.3,-12.21,;4.96,-12.98,;3.63,-12.21,;2.29,-12.98,;3.63,-10.66,;2.3,-9.89,;4.96,-9.87,;6.3,-10.65,;7.63,-9.87,;7.63,-8.33,;8.98,-10.64,;10.31,-9.87,;11.65,-10.62,;12.98,-9.85,;15.15,-9.38,;15.16,-10.46,;13.44,-11.25,;12.67,-12.46,;14.32,-11.58,;15.91,-12.53,;16.7,-11.39,;14.32,-10.2,)| Show InChI InChI=1S/C18H25ClN2O3/c1-23-17-9-16(20)15(19)8-14(17)18(22)24-7-6-21-10-12-2-3-13(11-21)5-4-12/h8-9,12-13H,2-7,10-11,20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.80	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description 5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair