Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50056422'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (RAT)	BDBM50056422 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(2,6-dim...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CC(C)OC(C)C1 Show InChI InChI=1S/C16H23ClN2O4/c1-10-8-19(9-11(2)23-10)4-5-22-16(20)12-6-13(17)14(18)7-15(12)21-3/h6-7,10-11H,4-5,8-9,18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligand				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50056422 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(2,6-dim...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CC(C)OC(C)C1 Show InChI InChI=1S/C16H23ClN2O4/c1-10-8-19(9-11(2)23-10)4-5-22-16(20)12-6-13(17)14(18)7-15(12)21-3/h6-7,10-11H,4-5,8-9,18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description 5-hydroxytryptamine 4 receptor antagonist activity, concentration which gave 50% reduction of the 5-HT-induced contractions in the guinea pig ileum				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair