BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM94630'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM94630 (4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	69.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptor				J Med Chem 46: 702-15 (2003) Article DOI: 10.1021/jm020270n BindingDB Entry DOI: 10.7270/Q25H7H06
Dainippon Pharmaceutical Co. Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM94630 (4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Tested for affinity against 5-hydroxytryptamine 4 receptor in the myenteric plexus of the guinea pigileum.				J Med Chem 46: 319-44 (2003) BindingDB Entry DOI: 10.7270/Q2T72J6J
INSERM Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM94630 (4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM94630 (4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM94630 (4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM94630 (4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand				Bioorg Med Chem Lett 12: 967-70 (2002) BindingDB Entry DOI: 10.7270/Q2RF5TB7
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair