Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM28575'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28575 (1-sulfonylindazole, 6d | 3-(methylamino)-N-[1-(nap...) Show SMILES CNCCC(=O)Nc1ccc2cnn(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C21H20N4O3S/c1-22-12-11-21(26)24-17-10-9-16-14-23-25(19(16)13-17)29(27,28)20-8-4-6-15-5-2-3-7-18(15)20/h2-10,13-14,22H,11-12H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.20	-50.4	n/a	n/a	n/a	n/a	n/a	7.4	22
Wyeth Research					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2413-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.071 BindingDB Entry DOI: 10.7270/Q28K77CF
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